Ceoliac Disease

Question 1

Is this condition auto/immune

Answer 1

Yes

A true gluten intolerance

Question 2

What’s are some sights and symptoms associated with coeliac disease

Answer 2

• rash - dermatitis hypertiformis
• diarrhoea
• constipation
• passing gas
• anaemia
• weight loss
• hair loss

Question 3

Gluten is made it of which 2 protiens?

Answer 3

Gliadin + Glutenin

Question 4

Food must contain how many ppm to be gluten free

Answer 4

20 parts per million

Question 5

What genes are present in coeliac disease

Answer 5

HLA DQ2 and HLA DQ8

HLA - human leukocyte antigens

Question 6

Is gluten involved in the stomach of starch in cells

Answer 6

Yes

Question 7

Is gluten digested well?

Answer 7

No, it is proline rich, no not digested well

Question 8

Will everyone with the genes for coeliac develop the disease

Answer 8

No, external factors are involved

Question 9

Which diagnosis techniques are involved

Answer 9

• HLA typing
• biopsy
• serum analysis for anti-glandin

Question 10

Treatment?

Answer 10

Gluten free diet

Question 11

The inflammatory response in the small intestine, causes damage and inflammation. Which deficiencies need to be considered?

Answer 11

• calcium, iron, folate, magnesium, B12, fat soluble vitamins

Question 12

Damage to the small intestine - causes damage to the villi. What is villi responsible for?

Answer 12

Absorption of nutrients

Damage to villi can lead to villious atrophy