Cerebrum - meiniges - neuroglia -brain barriers Flashcards

(52 cards)

1
Q

بسم الله الرحمن الرحيم
_________________
grey matter fromed of ?
white matter formed of?

A

grey : nerve cells - neroglia - blood capillaries
White matters: nerve fibers - neuroglia -blood capillaries

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2
Q

Cerebral cortex is thinnest in

A

preimary sensory area

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3
Q

Cerberal cortex is thickest in ?>

A

Motor area and assoication area

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4
Q

most numerous cells in cerebtal cortex ?

A

pyramidal cells

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5
Q

The apex of pyramidal cell directed to,,while the axons to,,,,,

A

surface
whilte matter

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6
Q

Cells of inner pyramidal layer project to spinal cord and brainstem as projection fibers ,,,,?

A

Corticospinal
Corticobulbar
Corticopontine projection fibers

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7
Q

Granule cells of cerebral cortex dexribe dendrites and axons

A

-dendrites short in the same layer others long to the surface
-Axons terminate in the deep cortical layers
__________________________

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8
Q

Fusiform cell describe/

A

SPINDLE shaped with axons from the middle of the body and dendrites from each side

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9
Q

Triangular cell in all layers
with ascending axons reaching the superifical layers

A

Cells of Martinotti

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10
Q

Spindle shape in superficial layers theri axons pass horizontally within these layers

A

Horizontal cells of caja l

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11
Q

Mention layers of cerebral cortex

A

moleuclar
External granular
External pyramidal
Internal granular
internal pyramidal
Plexiform

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12
Q

Layer of ceerebral cortex with
neuroglia
small horizontal neve cells
Tangential fibers

A

moleuclar layer!

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13
Q

External granular layer contains?

A

Closely packed granule cells dendrites asecding to molecular layer
axons deep to deep cortical layers

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14
Q

Small and medium pyramidal cells are in ?

A

Exteranl pyramidal layer

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15
Q

Outer band of baillarger appears in ?>

A

Internal granular layers with granule cells

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16
Q

Internal pyramidal layers contaitns?

A

Betz cells +
Inner band of baillarger

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17
Q

Plexifrom layer has

A

Mutliform cells + fusiform cells merging with white matter

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18
Q

comparre motor and sensory cortex

A

motor cortex thicker and has less granule cells than sensory cortex
and more pyramidal cells in layer 3 and 4 and 5

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18
Q

comparre motor and sensory cortex

A

motor cortex thicker and has less granule cells than sensory cortex
and more pyramidal cells in layer 3 and 4 and 5

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19
Q

Radial fibers of cerebral cortex dex

A

Afferents: thalamocortical
efferents : Corticospinal
corticonuclear cortioreticular corticopontine

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20
Q

Horizontal fibers of cerebral cortex

A

Tangential f
Outer and inner bands of Baillarger which are terminals of afferents to synapse with cortical fibers

21
Q

Single tough layer of fibrous tissue
Fused with periostem of the skull
Non Vascular
Separating and forming Dural venous sinuses
Inner surface lined by endothelium
separated from the arachanoid by subdural space

22
Q

Arahcnoid matter
it is ,,,,,,, layer with direct contact with dure
The outermost cells of the arachanoid (barrier cell) are bounded to one another by …….. that seal subarachanoid space from extracellular space in dura
Numerous Arahcnoid trabculae of ,,,,,,,and,,,,,,,,,, cross subarachanoid space reach
In certain areas arahacnoid projects to the dural venous sinuses forming ,,,,,,,,,,

A

Fibrocellular
))))))))))))))
Tight junctions
_______________
Fibrous collagen elastic
________________________
Arahcnoid villi in venous sinuses

23
Q

Pia matter
It invest brain completely
Covering gyri lining sulci
Fusing ,,,,, of the CNs and with ,,,,,, to form choroid pleux
Fibrocellular layer:!
Contaitn layre of ,,,,, cells joined by ,,,,,,, and,,,,,,,,and,,,,,,,,,

A

epinureium
ependymals
______________
Leptomeneingeal
Desmosmes
,gap junctions and
tight junctions

24
Choroid pleux function site
sECRETION OF CSF In 3rd and 4th venticle part of lateral ventricle villi in ventricular cavity core pia fenestarted blood capillaris covered by ependymals
25
Neuroglia shown by
silver and gold
26
Peripheral neuroglia is ,,,,,,, central neuroglia are ?
schamoamnn stellate ___________________ Astrocytes oliogdendroglia Microglia Epndymal cells origin site shape nucelus types
27
Astro(c)ytes Origin ?
Ectodermal 1
28
Astrocytes site?
White and grey matter most numerous glial cells STAR Shaped Fibrous astrocytes white matter long thin process Protoplasmic astro grey short extensive process
29
Glial fibrillary acid protin G FAB from astrocytes is
Marker of tumors
30
Long process of astrocytes terminate on Blood vessles as Neurons as Pia matter as Ependymal as?
Blood brain barrier Maintaining microenvironment Pia glial limtian Ependymal inner glial limitans
31
Nucleus of astrocytes are
Central round Vesiculkar cytoplam basophilic
32
special astrocytes as ?
=Mullers of Retina Radial =PITUICYTS in Pars Nervosa from pituitary
33
Functions of astrocytes? : support...... Regulation of brain ..... Removing ,,,,,and,,,,,,,,,,and,,,,,,,harmful to neurons After injury Proliferating to ...........by......... or ............. Share in fromation of !!!!!
CNS Metabolism K ions , NTs execess!, proteins Close defects gliosis or differetniating as stem cells _______________ BBB blood brain barrier
34
Oligodendro(c)tyes origin
Ectodermal as astrocytes in white matter
35
Mention oligodendrocyts types
Light cells : in CNS of neonate and fetus with echromatic nuclei and pale cytoplasm Darks cells : in CNS of adults heterochrmoatic mucelis and denese cytoplasm, ------GFAP
36
Mention function of oligodendtocytes :
A single oligodenedrocytes can invilve 50 axons Mylination for insulation
37
(m)icroglia origin ?
MesodermaaaaaalBlood monocytes ! grey and white matter of brain and spinal cord retina and ptic nerve
38
Cells with dense elongated nuceli Spindle rod shape Scanty cytopalms Mesodermal!
Microglia
39
Microgliosis ocuure in ?
Neurodegenrative disease as Alzhemir nad parkinsonism
40
Microglia function ?
Immune for phagocytosis
41
Mention types of ependmal cells
Lining ependymal Speical empdymal Tanycytes
42
Edpneymal cells orign and site
Ectodermal lining ventricles + Cental canal of spinal cord
43
Describe ependymal cells types
simpe cuboidal or coulmnar ciliated to move CSF Joined by?!! Desmosomes
44
Choroid pleux is
Vascular pia containing Fenestrated blood capillaries covered by modifed ependymals Apical microvilli Tigth junctions Basal infoldings and Mitochondria
45
Brain CSF barries formed of ?
Epednymal cells CT foot porcess of astrocytes
46
Blood CSF barrier ?
Fenestrated endotheliial Blood capilalries Contiuous Basement membrane Connnective tissue Epdenymal cells
47
Blood brain barrier formed of ?
Contiuonus endothium COntious basment membrane Pericytes Astrocytes surrounding basal lamian
48
Functions of Blood brain barrier
For modulation of enetry of metabolits preventing toxins regulating ions and NTs enetery
48
Functions of Blood brain barrier
For modulation of enetry of metabolits preventing toxins regulating ions and NTs enetery
49
fUNCTIONS OF pericytes
HAS functions in production and Maintainance of tigh juncitons Capillary angiogensis Share in Blood brain barrier
50
الحمدلله رب العالمين