Ch 1 Flashcards

(30 cards)

1
Q

Limbic region includes

A
Hippocampus 
Amygdala 
Hypothalamus 
Parahippocampal gyrus
Cingulate cortex
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2
Q

Hippocampus role

A

Memory

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3
Q

Amygdala role

A

Important element of fear circuitry and assigning emotional valence to stimuli

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4
Q

Frontal lobe involved in

A
Planning 
Attention
Abstract thought 
Problem solving 
Judgement 
Inhibition of impulses
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5
Q

Involved in emotion and memory

A

Limbic system

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6
Q

part of brain known for its role in motor coordination and learning. Also fir cognitive &affective processes

A

Cerebellum

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7
Q

Major relay station for sensory information

A

Thalamus

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8
Q

Part of the brain that plays a critical role in Neuroendocrine regulation

A

Hypothalamus

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9
Q

Mood, motivation, sexual drive, hunger, temperature, and sleep (brain region)

A

Hypothalamus

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10
Q

Two classes of cells in the brain

A

Neurons and glia

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11
Q

Neurotransmitter characteristics

A

Synthesized within the presynaptic neuron

Released with depolarization from the presynaptic neuron to exert a discrete action on the postsynaptic neuron

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12
Q

They are action on the postsynaptic neuron can be replicated by administering a drug

A

Neurotransmitter

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13
Q

What are neurotransmitters made up of

A

Amino acids, biogenic amines, nitrous oxide, larger peptides (opioids &substance P)

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14
Q

Amino acids

A

Glutamate

GABA

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15
Q

Monoamines

A
Dopamine 
Norepinephrine 
Epinephrine 
Serotonin 
Histamine
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16
Q

Small molecule neurotransmitter

A

Acetylcholine

17
Q

Peptide neurotransmitters

A
Opioids
Hypothalamic factors (CRH,orexins)
Pituitary hormones ((ACTH, TSH, oxytocin,vasopressin)
CNS peptides (sub p, etc)
Leptin
18
Q

Rapid a fact Nero transmitter receptor

19
Q

Not essential amino acid neurotransmitter that does not cross the blood brain barrier

20
Q

Synthesis of glutamate neurotransmitter relies entirely on conversion from its precursors___&___

A

Glutamine and aspartate

21
Q

What do NMDA receptor’s and anti-receptors mediate?

A

They mediate long-term potential in the hippocampus, a process critical for hippocampal dependent memory formation

22
Q

Large calcium and flex resulting in cell death

A

Excitotoxicity

23
Q

Synthesized from glucose, converted via Krebs cycle into a-ketoglutarate then glutamate 

24
Q

Neurotransmitter functioning in CNS and peripherally. Also a neuromodulator potentiated in the excitability of other neurotransmitter systems

25
Nero transmitter important role in central and peripheral neurophysiology.
ACH
26
Precursor of ACh
Choline
27
Anti-cholinergics medication‘s affect the balance of _&_. Can improve EPS in pts with movement disorders
Dopamine and ACh
28
Histamine stimulates
Wakefulness, suppresses appetite, may enhance cognition through its excitatory effects on brain stem and hypothalamic neurons
29
What brain territory is most likely considered as the major relay station for incoming sensory information
Thalamus
30
Dry mouth, constipation, urinary hesitancy, poor concentration side effects from binding to what receptors?
Muscarinic cholinergic receptors