CH 1 Arthritic/skeletal/soft tissue conditions

Question 1

DJD/OA is characterized by

Answer 1

degeneration of articular cartilage, with hypertrophy of subchondral bone and joint capsule of weight bearing joints

Question 2

Medications for OA:

Answer 2

cortiscosteroids, NSAIDS; Glucocorticoids are injected in to joints that are inflamed and not responsive to NSAIDS

Question 3

Diagnostic tests reveal what for DJD/OA

Answer 3

diminished point space, decreased height of articular cartilage and osteophytes

Question 4

What is ankylosing Spondylitis

Answer 4

progressive inflammatory disorder of unknown etiology

Question 5

Ankylosing Spondylitis begins in the

Answer 5

axial skeleton

Question 6

The initial onset of ankylosing spondylitis is typically in what decade of life

Answer 6

before the fourth decade

Question 7

First symptoms of ankylosing spondylitis

Answer 7

mid and low back pain, morning stiffness and sacroiliitis

Question 8

Advanced ankylosing spondylitis is characterized by

Answer 8

degeneration of peripheral and costovertebral joints

Question 9

ankylosing spondylitis effects ___ 3x more than __

Answer 9

men, women

Question 10

2 drugs besides NSAIDS/corticosteroids for ankylosing spondylitis

Answer 10

Cytotoxic drugs - block cell growth and Tumor necrosis factor inhibitors

Question 11

Diagnostic test for ankylosing spondylitis:

Answer 11

HLA-B27

Question 12

What is Gout

Answer 12

genetic disorder of purine metabolism characterized by elevated serum uric acid

Question 13

Where is gout most frequently observed

Answer 13

knee and great toe

Question 14

Specific NSAID for gout

Answer 14

indomethacin

Question 15

Diagnostic test for gout

Answer 15

lab tests identify monosodium rate crystals in synovial fluid or connective tissue samples

Question 16

What is psoriatic arthritis

Answer 16

chronic, erosive inflammatory disorder of unknown etiology

Question 17

2 drugs for psoriatic arthritis

Answer 17

DMARDS - disease modifying anti rheumatic drugs; BRM: biological response modifiers

Question 18

What is rheumatoid arthritis

Answer 18

chronic systemic disorder involving a symmetrical pattern of dysfunction of synovial tissues of hands, wrists, elbows, shoulder, knees ankles and feet

Question 19

Most effected joints in RA

Answer 19

MCP and PIP

Question 20

Characteristic of RA

Answer 20

pannus formation, ulnar drift and volar subluxation of MCP joints; DIPs usually spared; swan neck and boutonniere deformity , Bouchard’s nodes (excessive bone formation on dorsal aspect of PIP)

Question 21

Juvenile RA onset is prior to age

Answer 21

16

Question 22

RA meds:

Answer 22

DMARDs, gold compounds, NSAIDS, immunosupresants, corticosteroids

Question 23

RA lab test results

Answer 23

increased WBCs and erythrocyte sedimentation rate. Hemoglobin/hematocrit shows anemia and RA factor is elevated

Question 24

what is osteoporosis

Answer 24

a metabolic disease that depletes bone mineral density/mass

Question 25

what is senile osteoporosis caused by

Answer 25

decrease in bone cell activity secondary to genetics or acquired abnormalities

Question 26

DDx ankylosing spondylitis and Spinal stenosis in history intake

Answer 26

Ankylosing spondylitis: morning stiffness, sharp pain to an ache, bilateral SI pain referring to posterior thigh. Spinal Stenosis: intermittent aching pain, may have neurogenic intermittent claudication

Question 27

imaging DDx ankylosing spondylitis and stenosis

Answer 27

AS: plain films, stenosis: CT scan

Question 28

Osteomalacia is characterized by

Answer 28

decalcification of bones due to Vit D deficiency

Question 29

Osteomyelitis

Answer 29

an inflammatory response within bone caused by an infection

Question 30

most common infection cause in osteomyelitis

Answer 30

staphylococcus aureus

Question 31

Arthrogryposis multiplex congenita

Answer 31

contractures, sausage like limbs

Question 32

Osteogenesis imperfectA

Answer 32

Autosomal dominant; abnormal collagen synthesis leading to an imbalance between bone deposition and reabsorption.

Question 33

osteochondritis dissecans

Answer 33

separation of articular cartilage from underlying bone; typically medial femoral condyle

Question 34

when is surgical care of myositis ossificans warranted

Answer 34

only non hereditary and after maturation of the lesion (6-24 months)

Question 35

difference between CRPS I and II

Answer 35

both have dysfunction in the sympathetic nervous system but I has no underlying nerve injury and II has a nerve injury

Question 36

Paget's disease

Answer 36

abnormal osteoclastic and osteoblastic activity

Question 37

For less than ___degrees scoliotic curve, PT is indicated

Answer 37

25

Question 38

spinal orthosis for scoliosis is indicated for _______degrees

Answer 38

25-45 degrees