Ch. 17 Drug Cards - Psychoses

Question 1

Chlorpromazine Therapeutic Class

Answer 1

First-generation antipsychotic; schizophrenia drug

Question 2

Chlorpromazine Pharmacologic Class

Answer 2

D2 dopamine receptor antagonist; phenothiazine

Question 3

Chlorpromazine education for the patient

Answer 3

Must take for 7-8 weeks before improvements take place

Question 4

Chlorpromazine administration alert

Answer 4

Give deep IM, ONLY in the UPPER OUTER QUADRANT of the buttocks

Patient should remain SUPINE for 30-60 minutes after injection and then rise slowly

Question 5

Extrapyramidal symptoms (EPS) - older, female, and pediatric patients who are dehydrated

Neuroleptic malignant syndrom (NMS)

Answer 5

Chlorpromazine adverse effects

Question 6

Chlorpromazine drug interactions

Answer 6

Interacts with several drugs - avoid sedative medications (phenobarbital)

Question 7

Chlorpromazine treatment of overdose for EPS

Answer 7

Treated with: Antiparkinsonism drugs
Barbiturates
Anticholinergics (benztropine [Cogentin])

Question 8

haloperidol (Haldol) Therapeutic Class

Answer 8

Conventional antipsychotic; schizophrenia drug

Question 9

haloperidol (Haldol) Pharmacologic class

Answer 9

D2 dopamine receptor antagonist; NONPHENOTHIAZINE

Question 10

haloperidol (Haldol) actions and uses:

Answer 10

Acute and chronic psychotic disorders
Unprovoked aggressiveness and explosive hyperexcitability

Question 11

haloperidol (Haldol) patient education

Answer 11

Do not abruptly discontinue, or severe adverse reactions may occur

Question 12

haloperidol (Haldol) adverse effects

Answer 12

Incidence of EPS is high

Question 13

haloperidol (Haldol) drug interactions

Answer 13

Interacts with MANY drugs

Question 14

haloperidol (Haldol) treatment of overdose

Answer 14

With EPS, antiparkinsonism medication should be administered

Question 15

risperidone (Risperdal) Therapeutic Class

Answer 15

Atypical antipsychotic; schizophrenia drug

Question 16

risperidone (Risperdal) effects occur where?

Answer 16

Primarily from blockade of dopamine type 2, serotonin type 2, and alpha2-adrenergic receptors located within the CNS

Question 17

risperidone (Risperdal) patient education

Answer 17

Several weeks are required for therapeutic effectiveness
When switching from other antipsychotics, discontinue medications to avoid overlap

Question 18

risperidone (Risperdal) Adverse Effects

Answer 18

EPS (involuntary shaking of the head, neck, and arms)
May cause weight gain and hyperglycemia

Question 19

risperidone (Risperdal) contraindications

Answer 19

Older Adults with dementia-related psychoses - at increased risk for heart failure, pneumonia, or sudden death

Patients with underlying cardiovascular disease - may be prone to dysrhythmias and hypotension

Avoided in patients with a history of seizures, suicidal ideations, or kidney or liver disease

Question 20

risperidone (Risperdal) drug interactions

Answer 20

Avoid CNS depressants (alcohol, antihistamines, sedative-hypnotics, or opioid analgesics)

Due to inhibition of liver enzymes, other drugs that increase adverse effects include:
SSRIs - paroxetine, sertraline, and fluoxetine, and the azole antifungal drugs

Question 21

risperidone (Risperdal) lab tests

Answer 21

Increased liver enzymes (ALT & AST)
Anemia
Thrombocytopenia
Leukocytosis
Leukopenia