CH 19 Flashcards

(50 cards)

1
Q

The reactant in an enzyme-catalyzed reaction is called the

A

Substrate

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2
Q

The theory of enzyme mechanism that suggests a rigid, inflexible molecule is the ________ model

A

Lock and Key

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3
Q

The theory of enzyme mechanism that suggests a flexible molecule whose shape is altered by the reaction conditions is the ________ model.

A

Induced fit

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4
Q

When substrate molecules occupy all of the active sites in the enzyme available for a particular reaction, the enzyme is said to be

A

saturated

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5
Q

Substances the bind to an enzyme and increase its activity are called

A

positive regulators

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6
Q

A multi-step biochemical process in which the rate of an early step is affected by the concentration of products of a later step is said to be subject to

A

feedback control

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7
Q

The mechanism of enzyme control that is similar to noncompetitive inhibition because both involve interactions with the enzyme at locations other than the active site is

A

allosteric interaction

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8
Q

Another term for substances that bind irreversibly with the active site of an enzyme is

A

POISONS

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9
Q

You have added an irreversible inhibitor to a sample of enzyme and substrate. At this point, the reaction has stopped completely. What is the best way to get the activity of the enzyme back up?

A

The enzyme is inactive at this point. Nothing can be done except add new enzyme.

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10
Q

You have an enzymatic reaction going at optimum pH and optimum temperature. You add a competitive inhibitor to the reaction and notice that the reaction slows down. What can you do to speed the reaction up again?

A

Add more substrate; it will out-compete the inhibitor and increase the rate.

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11
Q

Which of the following statements about the effect of temperature on enzyme activity is correct?

A

Enzymes in human body usually give best catalytic activity around 37 °C

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12
Q

Fat Soluble Vitamins are…

A

A D E K

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13
Q

Transferase

A

type of enzyme that catalyzes the transfer of functional group from molecule to another

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14
Q

Zymogen

A

inactive form of an enzyme, PROENZYME

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15
Q

Hydrolase

A

type of enzyme that catalyzes the breakdown of LG molecules by the RXN of H2O

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16
Q

Isomerase

A

type of enzyme the catalyzes internal rearrangement of molecules

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17
Q

Antioxidant

A

Prevents harmful RXN of free radical

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18
Q

Oxidoreductase

A

Type pf enzyme that catalyzes oxidation or reduction RXNs

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19
Q

Lyase

A

enzyme that catalyzes the removal of a small molecule from a larger one

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20
Q

Vitamin

A

small organic molecule necessary for good health and must be obtained from diet

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21
Q

Hormones produced in the…

A

endocrine system

22
Q

Chemical messengers that are produced by the endocrine system and circulate in the bloodstream are

23
Q

Chemical messengers that carry signals between neurons are

A

neurotransmitters

24
Q

**Depression is known to be caused by a deficiency of

A

serotonin.
dopamine.
norepinephrine.

25
The organ that is above the pituitary gland...controls the endocrine system is the
hypothalmus
26
Receptor
pt of target cell that interacts w/ the messenger
27
Endocrine System
cells in organs and tissues that secrete hormones thru blood stream
28
Direct Neural control
nervous sys. message from the hypothalamus-->initiates hypothalamus release of hormones by the ADRENAL glnd
29
Direct Release of Hormones
Hormones move from hypothal.-->posterior pituitary gland where they are stored until needed
30
Indirect control three release of regulatory hormones
regulatory hormones from hypothalmus STIMULATE or inhibit release of hormones by pituitary gland
31
Second Messanger
chemical mesg. released inside cell when hydrophilic hormone or neurotransmitter interacts w/ a receptor on the cell surface
32
Epinephrine
ADRENALINE - fight or flight hormone - released by adrenal gland in instant response to danger
33
Does Epinephrine make glucose more available?
YES
34
What does Epinephrine in flight or flight response?
incurs blood pressure, heart rate, and respiratory rate
35
what counteracts respiratory spasms? treats anaphylaxis
Epinephrine
36
Biochemistry
study of molecules and their RXNs in living organisms - PRO - CHO - LIPIDS - NUCLEIC ACIDS
37
Protein
LARGE biological molecule maced of many amino acids linked together thru AMIDE PEPTIDE BONDS
38
Amino Acid
molecules that contains both an amino group and a carboxylic acid functional group
39
Alpha (a) amino acid
amino acid in which the amino group is bonded to the carbon atoms next to the -COOH grp
40
Side Chain(amino acid)
the variable group bonded to the central carbon atom in an amino acid-different in different amino acids!
41
Peptide bond
amide bond that links together two amino acids together
42
Amino acid facts
- ALL PRO are built from just 20 a-amino acids - Each amino acid=written shorthand 3 letters (his) - 19 of amino acids differ only in the identity of the side change attach to alpha carbon - Last amino acid (proline) is a secondary amine whose N+ and alpha- Carbon atoms are joined in a five member ring
43
Essential Amino Acids
cannot be synthesized by the organism- MUST BE SUPPLIED IN DIET
44
Conditionally Essential Amino acids (CAA)
their synthesis can be limited under special pathophysiological conditions -such as prematurity in the infant or individuals in severe catabolic distress
45
SIX CAA
- Arg - Cys - Try - Pro - Gln - Gly
46
Properties of A.A
Classified as acidic, neutral, basic further classified as those w. non polar side chains and those w. polar side chains Intermolecular forces are very important in determining PRO structure
47
Noncovalent forces
forces of attraction other than covalent bond that can act b/t molecules or w/in molecules
48
A.A Side chain classification
Non polar SC are described as HYDROPHOBIC, polar, acidic, basic side chains are described as HYDROPHILLIC
49
Hydrophobic
"water fearing" a hydrophobic substance that DOES NOT dissolve in H20
50
Hydrophillic
"water loving" a hydrophilic substance DOES dissolve in H20