Ch. 23 Kidneys Flashcards
(41 cards)
Functions of kidneys?
- Regulate: Fluid, electrolytes, acid-base
- Secrete renin: regulates B.P.
- Produce erythropoietin: Stimulates RBC prod. in bone marrow
- Convert Vit. D to active form: Regulates Ca levels
Characteristics of AKI?
- Kidney function deteriorate rapidly
- Decreased urine output
- Altered blood composition
- Can be reversible but could also lead to CKD
Cause locations of AKI?
- pre renal
- intra renal
- post renal
Pre renal injury and examples?
Sudden reduction in blood flow to kidneys
- low blood volume
- Renal artery disorders
- Heart disorders
Intra renal injury and examples?
Things that damage kidney tissue
- Vascular disorders: DM, Sickle cell, Transfusion
- Obstructions within: Tumors, scar tissue, stones
- Renal injury: infection, drugs, e. coli
Post renal injury and examples?
Things that affect urine excretion
- obstructions: strictures, tumors, stones
- Bladder disorders: rupture, nerves
- Pregnancy
Labs for Kidney disease?
- BUN: Blood urea nitrogen-Elevated
- CR: Creatinine- Elevated
- UA: Uric acid- Elevated
- GFR: Glomerular Filtration Rate- Decreased
The following cards are consequences of AKI…
- Oliguria
- Anuria
- Inadequate waste filtering
- Edema
- Uremia
- Uremic Syndrome
- Metabolic alterations
Oliguria
Really low production of urine
Anuria
No urine production
Inadequate waste filtering
Hyperkalemia, hyperphosphatemia, hypernatremia, hypermagnesemia in blood.
Edema
Fluid collection in face, hands, feet, ankles because of high sodium levels.
Uremia
High nitrogen containing compounds in the blood
Uremic Syndrome
.
Metabolic alterations
Extracellular fluid protein catabolism Amino acid metabolism Insulin resistance reduction of lipolysis depletion of antioxidant system induce inflammation Immunodeficient
Goals for treatment of AKI?
- Individualized
- Restore fluid and electrolytes
- Minimize waste products in blood
-Can include both medical and nutrition management
Medical management of AKI?
- Treat underlying symptoms: problem may correct itself
- Manage symptoms
- Drug therapy: Diuretics, reduce doses of meds if no dialysis, potassium and phosphate binders
- Dialysis: Will need to increase doses of medications
Nutrition therapy for AKI in following cards
- Energy
- Protein
- Fluids
- Electrolytes
Energy
25-35 kcal/kg dry body weight
Monitor body weight over time to be sure intake is adequate
Protein
- No dialysis: 0.8-1.0 g/kg dry body weight/day
- Dialysis: 1.0-1.7 g/kg dbw/day
Fluids
- Assess status from weight differences, b.p., and a physical
- Replace fluids to prevent dehydration: Urine output+500mL/day
- Can assess adequacy of intake from blood sodium levels
- Hyponatremic: excess fluid intake
- Hypernatremic: inadequate fluid intake
Electrolytes
*Only change if blood levels are out of range
Potassium: 2,000-3,000 mg/day
Sodium: 1,000-2,000 mg/day
Phosphorus: 8-15 mg/kg dbw/day
Characteristics of CKD?
- Gradual, irreversible kidney damage
- Progresses over many years, usually w/o symptoms
- Caused by: DM, Uncontrolled hypertension, genetics, inflammation, and immunological disorders
What is going on in the kidneys with CKD?
Nephrons enlarge to handles excess load
Enlargement causes deterioration of nephrons
More and more nephrons fail over time