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Flashcards in Ch 25 Deck (29)
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1

What organ metabolizes Tylenol

Liver

2

Peak

max effect of drug

3

Trough

lowest effect of drug

4

half-life

amount of time it takes of half of the drug to be used

5

Primary effect

what we want to see

6

Secondary effect

unintended

7

side effect

-unintended
-may be predictable
-results in physiological effect

8

Adverse effect

-harmful
-unintended
-unpredictable
-Stop drug immediately

9

standing orders

-set standards

10

T.O.

Telephone order

11

V.O.

verbal order

12

HAMS

High Alert Medications
-Insulins
-Heparin
-Sedatives
-Opoids

13

3 checks

-Before you pour
-After you pour
-At bedside

14

Six Rights of medication administration

-patient
-drug
-dose
-rout
-time
-frequency

15

Pharmacokinetics

-What happens to the drug in the body

16

Pharmacodynamics

-How the drug affects the body

17

4 processes of pharmacokinetics

-ADME

18

Absorption

-Movement of drug in the bloodstream
-Factors affecting absorption
route of administration
drug solubility
pH/ionization
blood flow

19

Distribution

-Drug transport to tissues and organs
-Factors affecting distribution
local blood flow
membrane permeability
protein-binding capacity

20

Biotransformation

-Chemical conversion of drug
-Factors affecting metabolism
liver function
health/disease status
first-pass effect

21

Excretion

-Elimination of the drug
-Factors affecting excretion
organ function, especially the kidneys, and lungs
Exocrine glands

22

The client has been on a low-protein diet. This will most likely affect which pharmacokinetic process?

Distribution

23

Primary effects of drugs

-Therapeutic effects
-Predicted
-Intended
-Desired
-Why the drug was prescribed

24

Secondary effects of drugs

-Unintended
-Nontherapeutic
-Can be: predictable, harmless, harmful

Types:
side effects
adverse reactions
toxic reactions
allergic reactions
idiosyncratic reactions
cumulative effect

25

Routes of administration: oral meds

-Most commonly used route
-Tablets, pills, capsules
-Liquids
-Buccal
-Sublingual
-Enteral meds

26

Routes of administration: Topical meds

-Applied directly to the skin
-Local and sometimes systemic effects
-Lotions/creams
-transdermal patches
-eye and ear
-nasal
-vaginal
-rectal

27

Routes of administration: Respiratory inhalations

-Use concept of nebulization
-Absorbed via alveoli and blood supply
-atomizers
-aerosol
-metered dose inhaler

28

Routes of administration: Parenteral meds

-Intradermal
-trasdermal
-subQ
-IM
-IV

29

Which administration route would allow medications to be absorbed fastest

IV