Ch. 26 - Corynebacterium Flashcards Preview

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Flashcards in Ch. 26 - Corynebacterium Deck (5)
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1
Q

Corynebacterium

A
Aerobic G+b
coryneform bacilli (club) 
CAT +
Ferment carbs
Non-motile

Metachromatic granules

Colonize human skin, URT, GI, GU
Opportunistic pathogen

2
Q

Corynebacterium diphtheriae

A

Pleomorphic G+B with metachromatic granules

4 biotypes: belfanti, gravis, intermedius, mitis

Diphtheria toxin - major virulence
exotoxin produced at infection site, spreads thru blood
org doesn’t need to be in blood to cause disease

Humans only known reservoir

3
Q

Corynebacterium diphtheriae disease

A

Diphtheria: clinical presentation is determined by site of infection, immune status of patient, virulence of organism

  • Respiratory diphtheria: exudative pharyngitis that develops into thick pseudomembrane (adheres to underlying tissue), systemic illness in severe cases: myocarditis, congestive heart failure, cardiac arrhythmias
  • Cutaneous diphtheria: acquired through skin contact, papule develops turning into chronic non-healing ulcer
4
Q

Corynebacterium jeikeium

A

Aerobic G+b

Opportunistic pathogen in immunocompromised

5
Q

Corynebacterium urealyticum

A

Aerobic G+b

Urinary tract pathogen

Urease + –> makes urine alkaline –> renal stones