Ch. 40, 97-100 Flashcards
(27 cards)
What are helminths
-treatment
parasitic worms
-anthelminths to treat
Nematoda are
round worms
Cestoda are
tapeworm
Tematoda are
Flukes
Mebendazole
- treat
- M/A
- time to effect
- A/E
- pregnant
Intestinal roundworms
- Act by inhibiting glucose uptake by worm causing death over 3 days
- Abdominal pain, D
- Avoid pregnant women
Albendazole
- treat
- M/A
- A/E
- Pregnant
Cestodes and nematodes
- acts by inhibiting uptake of glucose in worm
- Liver impair- Check LFTs
- Avoid pregnant women
Pyrantel
- treat
- M/A
- A/E
Nematodes
- Causing flaccid paralysis of parasites and then excretion from body occurs
- NVD, CNS irritability
Cause of Malaria
protozoa of plasmodium
Mararia symptoms
-why
chills, fever, sweating
-response by the body to the continued lysis of RBCs with protozoa present
Vivax Malaria
- Cause length to show
- length
- Symptoms
- Relapse
- Treatment success
- caused by plasmodium vivax
- 26 days until symptoms appear
- mild, fever every 2 days
- High relapse due to dormant parasites in the liver ceases entirely in about 2 years
- Drug resistant is uncommon
Falciparum Malaria
- Length to show
- Symptoms
- Relapse
- Treatment success
- 12 days for symptoms to appear
- severe, 60% erythrocytes can be destroyed, *anemia and weakness, *Dark urine, *Pulmonary edema, *hypoglycemia, *toxic encephalopathy
- No relapse
- Drug resistance is common
What is radical cure
a drug that will kill dormant parasites in liver, preventing relapse
Chloroquine
- Use, Line
- M/A
- A/E
- Use with
- Take
1st line oral for cure
- mild to moderate acute attacks for P. Vivax and P. Falciparum
- Acts by causing heme accumulation within parasite
- Visual disturbance, pruritus, HA, and GI Effects, *ototoxicity, liver disease
- Photophobic- sunglasses
- take with meals
Quinine
- Use
- M/A
- A/E
- Pregnancy
- Treat chloroquine- resistant malaria
- causing heme accumulation within parasite
- Cinchonism (Tinnitus, HA, visual disturbances, N/D)
- Hemolysis in its with G6PD deficiency *Hypotension , * A-fib, *Hypoglycemia
- Pregnancy C
Amebiasis
- infects
- symptoms
- Primary infects intestine
- asymptomatic, – D, wt loss
Crytosporidiosis
- infects
- transmitted
- symtoms
- infects intestinal tract
- transmitted by contaminated water, fruit, veggies
- DNV, anorexia, low-grade fever
Girdasis
- infects
- transmitted
- symptoms
- intestine with migration to bile ducts and gallbladder
- contaminated water or object
- malaise, heartburn, VD, colicky pain after eating, malodorous belching, flatulence
Toxoplasmosis
- affects
- deadly to who
- brain, eyes, liver and other organs leading to encephalitis and death
- immunocompromised (AIDS)
Metronidazole
- Use
- M/A
- A/E
- When to stop
- Drug interactions
- Pregnancy
- used to treat symptomatic intestinal amebiasis and systemic amebiasis, giardiasis, trichomoniasis
- Alters synthesis of DNA
- NVD, HA, dry mouth, *Metallic taste, Stomatitis, insomnia, vertigo, weakness
- 1st sign of neuro issues
- Alchohol, Warfarin (decrease dose), Phenytoin, lithium, fluouracil, cyclosporine, and tarcilimus
- Avoid 1st trimester
What is scabies
- where infected
- manifests as
- transmitted
infestation with mites
- elbows, nipples, navel, genital region and web on fingers
- itching
- towels, linen or clothing
Pediculosis is
-where
Infestation with lice
- Phthirus pubis ( Pubic lice)
- Pediculuc humanus capitits- (Head Louse)
- Pediculus humanus corporis (Body louse)
Permenthrin
- M/A
- Failure %
- A/E
- killing mites, lice and their ova by causing paralysis
- 5% missed
- Itching, erythema, Edema, buring, stinging and numbness
Malathion
- Use
- A/E
- Kill lice and ova
- devoid serious A/E
Heroin
- Age group
- Behavioral effects
- Route(s)
- 18-25, social
- 45 sec orgasm, Euphoria, N/V
- IV, Smoking, Nasal- Lipid Soluble