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NAPLEX Review UWorld > Ch 6: Drug Formulations & Patient Counseling > Flashcards

Ch 6: Drug Formulations & Patient Counseling Flashcards

(64 cards)

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1
Q

What are the benefits Osmotic controlled-release oral delivery systems (OROS)?

A

Decreased frequency of drug administration due to its extended-release formulation

Afast drug delivery due to the rapid dissolution of the overcoat, which allows for a quicker onset of action

Reduced fluctuations in serum drug levels due to the controlled release of drug as the OROS is activated

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2
Q

Brand:Generic

Detrol LA

A

tolterodine

Tx overactive bladder symptoms

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3
Q

Brand:Generic

Rapamune

A

sirolimus

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4
Q

Brand:Generic

Suprax

A

cefixime

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5
Q

Brand:Generic

Mycelex

A

clotrimazole

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6
Q

Brand:Generic

Cepacol

A

benzocaine/menthol

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7
Q

Brand:Generic

Nurtec

A

rimegepant

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8
Q

Brand:Generic

Remeron SolTab

A

mirtazepine ODT

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9
Q

Brand:Generic

Zyprexa Zydis

A

olanzapine ODT

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10
Q

Brand:Generic

Edluar

A

zolpidem SL

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11
Q

Brand:Generic

Subsys

A

fentanyl SL spray

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12
Q

Brand:Generic

Actiq

A

fentanyl lozenge

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13
Q

Brand:Generic

Fentora

A

fentanyl buccal tab

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14
Q

Drugs that can be sprinkle on applesauce

A

Adderall XR - dextroamphetamine/amphetamine ER

Coreg CR - carvedilol

Dexilant - dexlansoprazole

Focalin XR - dexmethylphenidate

Namenda XR - memantine

Nexium - esomeprazole

Ritaline LA - methylphenidate

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15
Q

What can this drug be mix with?

Cambia (diclofenac potassium)

powder

A

water

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16
Q

What can this drug be mix with?

Creon

and other pancreatic enzyme products

A

on soft food w/ low pH:
applesauce
pureed pears or banana

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17
Q

What can this drug be mix with?

Depakote Sprinkles (valproic acid)

A

soft food

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18
Q

What can this drug be mix with?

Kadian (morphine)

A

applesauce or soft food

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19
Q

What can this drug be mix with?

potassium chloride ER

Capsules

A

applesauce or pudding

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20
Q

What can this drug be mix with?

Questran (cholestyramine)

Including Questran Light

A

2-6 oz of water or non-carbonated liquid

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21
Q

What can this drug be mix with?

Singulair (montelukast)

A

5 ml baby formula or breast milk OR
In a spoonful of applesauce, carrots, rice, or ice cream

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22
Q

What can this drug be mix with?

Vyvanse (lisdexamfetamine)

A

water
yogurt
orange juice

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23
Q

Which sweetener produces gas, cramping, & bloating?

In sensitive pts including those w/ IBS

A

Sorbitol

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24
Q

Which sweetener is dangerous for those w/ phenylketonuria (PKU)?

A

phenylalanine

Use in ODT, chewable, & granule

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25
# Brand: Generic Invega Sustenna | & Invega Trinza
paliperidone | LA IM injection
26
# Brand: Generic Risperdal Consta
reperidone | LA IM injection
27
# Brand: Generic Vivtral
naltrexone | LA IM injection
28
# Brand: Generic Zyprexa Relprevv
olanzapine | LA IM injection
29
# Self-Administered Injections Which ones require refrigeration?
glatiramer (Copaxone) etanercept (Enbrel) adalimumab (Humira) certolizumab pegol (Cimzia) golimumab (Simponi) teriparatide (Forteo) abaloparatide (Tymlos)
30
# Self-Administered Injections Which ones does not require refrigeration?
enoxaparin (Lovenox) fondaparinux (Arixtra) methotrexate (Otrexup) sumatriptan (Imitrex, Zembrace, SymTouch)
31
# Self-Administered Injections Which injection should you not rub the skin and why?
Anticoagulant injections (e.g. enoxaparin, fondaparinux) Can cause severe bruising
32
Which injections should not be shaken?
Monoclonal Antibodies
33
Most patches can be applied to?
Chest (upper) Back (upper & lower) Upper arm (on the part facing out) Flanks (sides of the body, abdomen level)
34
# Patch Site Exception Exelon
Normal sites except not on the flanks | Rivastigmine
35
# Patch Site Exception Butrans
Normal sites except the flank is chest level
36
# Patch Site Exception Which patches are applied the affected area?
diclofenac (Flector) lidocaine (Lidoderm, Salonpas) capsaicin (Qutenza)
37
# Patch Site Exception Where do you apply Daytrana?
hip | methylphenidate
38
# Patch Site Exception Where do you not apply estrogen patches?
breast
39
# Patch Site Exception Where do you not apply testosterone patches?
scrotum
40
Which patches can be applied to the buttock?
Xulane oxybutynin (Oxytrol) Vivelle-Dot
41
Which patches are applied twice daily?
diclofenac (Flector)
42
Which patches are applied daily ?
methylphenidate (Daytrana) - 2 hrs prior to school nicotine (NicoDerm CQ) rivastigmine (Exelon) rotigotine (Neupro) selegiline (Emsam) testosterone (Androderm) - nightly
43
Which patches are applied Q72H ?
fentanyl (Duragesic) - can be change to Q48H if it wears off after 48 hours scopolamine (Transderm Scop): Q72H PRN
44
Which patches are applied twice weekly?
estradiol (Alova, Vivelle-Dot) oxybutynin (Oxytrol)
45
Which patches are applied weekly?
donepezil (Adlarity) buprenorphine (Butrans) clonidine (Catapres-TTS) estradiol (Climara) - continuous or cyclic estradiol/levonorgestrel ethinyl estradiol/norelgestromin (Xulane, Zafemy) - cyclic ethinyl estradiol/levonorgestrel (Twirla) - cyclic ## Footnote Cyclic - 3 weeks on, 1 week off
46
Lidocaine patch instruction
1-3 patches daily PRN on for 12 hrs, off for 12 hrs | Lidoderm
47
nitroglycerin patches
1 patch daily, on for 12-14 hrs, off for 10-12 hrs
48
Which patches can be cut?
Lidoderm & Qutenza
49
What can be applied for skin irritation from the patch?
topical steroids (e.g. hydrocortisone) after removing the patch
50
Which patches has to be removed before an MRI?
clonidine (Catapres-TTS) rotigotine (Neupro) scopolamine (Transderm Scop) testosterone (Androderm)
51
Which patch can be covered by tape and what type of tape?
fentanyl & buprenorphine (Butrans) Bioclusive or Tegaderm
52
Which patches should be flush?
narcotic patches (e.g. fentanyl, Butrans) Daytrana
53
# Nasal Spray Counseling Before use
Shake gently Prime - 1st use or haven't used within 7-14 days Blow nose before use
54
# Nasal Spray Counseling Using
Close one nostril Breathe in through your nose then pres firmly & quickly down on applicator Breathe out through mouth Use for the labeled # of spray and discard, even if it's not empty Do not blow your nose after spray
55
# Eye Drop Counseling Before
Shake a few times Gels - inverted & shaken once
56
# Eye Drop Counseling After
Close eyes Press a finger between eye & the top of the nose for 1 minute
57
How many minutes between drops?
5 minutes between doses 5-10 minutes between medications 10 minutes between gels
58
Drops w/ benzalkonium chloride (BAK)
remove soft contacts & wait 15 minutes
59
Ear drop administration for adults
Pull ear up & back
60
Ear drop administration for childrens < 3 y/o
Pull ear down & back
61
# Ear drops How long do you stay on your side?
5 minutes
62
What is the position for administrating enemas?
Lying on the left side Left leg extended Right leg flexed forward Insert applicator tip slightly toward the navel
63
How long does the patient have to remainin in the same position after an enema?
30 minutes
64
How long do you need to keep the suppository in?
1-3 hrs

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