Ch 7

Question 1

What is the primary advantage of targeted cell therapy?

Answer 1

It uses drugs that selectively attack malignant cancer cells p.152

Question 2

Which target of both chemo and radiation treatment accounts for adverse and therapeutic effects?

Answer 2

Rapidly proliferating cells p. 149

Question 3

The leading cause of death in both men and women

Answer 3

Lung cancer p. 129

Question 4

Cell proliferation means?

Answer 4

Increase cell numbers by mitotic cell division p. 129-130

Question 5

Malignant neoplasms are more well-differentiated than benign tumors (true/false)

Answer 5

false p. 129-131

Question 6

Do cancer cells ever die?

Answer 6

They differ from normal cells by being immortal and have an unlimited lifespan p. 133-135

Question 7

A patient with liposarcoma has?

Answer 7

Malignant tumor of adipose tissue p. 131

Question 8

What is a polyp?

Answer 8

Growth that projects from a mucosal surface p. 130

Question 9

Benign tumors usually grow by expansion (true/false)

Answer 9

true

Question 10

Explain “sentinel node”

Answer 10

it is used to describe the initial lymph node to which the primary tumor drains p. 135

Question 11

Which tumor suppressor genes are associated with genetic susceptibility to breast cancer?

Answer 11

BRCA1
BRCA2
p.141

Question 12

With abdominal cancer the tumor may compress the viscera which causes?

Answer 12

Bowel obstruction p. 144

Question 13

breast tumor undetectable until it has double 30 times and contains more than 1 billion cells. Which means it measures at approx what size?

Answer 13

1 cm

p.134

Question 14

Adult cancers differ in origin from childhood cancers by:

Answer 14

Adult cancer originates from epithelial cells

p.130

Question 15

adolescent that had childhood cancer should include which following late therapy sequelae?

Answer 15

Impaired growth
Neurologic dysfunction
p.153

Question 16

What is the abnormal mass of tissue in which the growth exceeds and is uncoordinated with that of the normaltissue

Answer 16

neoplasm p. 136

Question 17

Goa of Antiangiogenesis therapy?

Answer 17

limit the size of a tumor by limiting its ability to recruit blood vessels p. 140

Question 18

What type of tissue composes the tumor of Adenocarcinoma?

Answer 18

Glandular epithelium p. 130

Question 19

5-fluorouracil stops normal development and division by interrupting the S phase of the cycel. Explain the S phase:

Answer 19

The synthesis of DNA occurs causing 2 sperate sets of chromosomes to develop p. 139

Question 20

significant loss of skeletal muscle and fat can be described as:

Answer 20

Cachexia p. 145

Question 21

What is the treatment that involves strengthening the immune system?

Answer 21

immunotherapy p.149-152

Question 22

Risk factors for cancer:

Answer 22

Age
Environment
Genetics
Heredity
p. 137

Question 23

Which cancers are often found because of effusions?

Answer 23

Lung and Ovarian cancers p. 144

Question 24

Drug therapies that affect cyclins and CDS are therapeutic by:

Answer 24

affecting the progression of cells through the process of cell division p. 137

Question 25

Carcinoma is suspected because cells possess the characteristics of:

Answer 25

loss of differentiation p. 132

Question 26

Healthy tips for preventing cancer identifies which foods/compounds to be carcinogenic in humans?

Answer 26

Cigarette smoke smoked foods nickel compounds p. 142

Question 27

Definition of anaplasia

Answer 27

loss of cell differentiation in cancerous tissue

Question 28

Cancers have been identified as inheritable through autosomal dominant gene. Which cancer carries the highest risk in someone who carries the gene?

Answer 28

Colon cancer p. 141

Question 29

radiation therapy is the best course of treatment for:

Answer 29

radiosensitive tumors that are fast growing p. 149

Question 30

Screening mechanisms are available for which cancers?

Answer 30

Breast Cervical prostate p. 147

Question 31

Three stages that cause normal cells to become cancerous:

Answer 31

Initiation Promotion progression p. 147-149

Question 32

Which factors are high-risk and associated with cancer development?

Answer 32

``` hormonal factors heredity environmental agents immunologic mechanisms p.144 ```

Question 33

drinking and smoking puts patients at risk for which cancers:

Answer 33

Laryngeal esophageal oral

Question 34

breast cancer staged as T3, N0, M0, what does this mean?

Answer 34

sizeable tumor but no lymphatic involvement p. 149

Question 35

Cancer-associated genes can be classified into which broad categories:

Answer 35

Gene overactivity Gene underactivity p. 137-140