ch0.1 -- misc vocabulary Flashcards
analgesia
inability to feel pain
bracketing technique
performing a sport movement with less than normal and greater than normal resistance; another form of acceleration training
dorsal
toward the posterior. from Latin dorsum, meaning ‘back’ – surface of an organism refers to the back, or upper side, of an organism. if talking about the skull, the dorsal side is the top.
ventral
toward the anterior. from Latin venter, meaning ‘belly’. surface refers to the front, or lower side, of an organism.
kyphotic
forward rounding of the back (hunchback); from ‘kyphos’ or ‘hump’ in greek. most common in older women and often related to osteoporosis.
lordotic
curving inward of lower back. some lordosis is normal, too much is referred to as swayback. lumbar lordosis makes you look like a chicken or goose.
rate coding
the rate at which the motor units are fired. as the intensity of a stimulus increases, the frequency or rate of action potentials, or “spike firing”, increases; rate coding is sometimes called frequency coding.
drag
a force acting opposite to the relative motion of any object moving with respect to a surrounding fluid. sometimes called air resistance, a type of friction, or fluid resistance.
surface drag
friction of a fluid passing along the surface of an object; in alternate words, drag caused by the friction of a fluid against the surface of an object that is moving through it.
form drag
fluid resistance from the way a fluid presses against the front or rear of an object passing through it
kinase
an enzyme that catalyzes the transfer of a phosphate group from ATP to a specified molecule
lactate vs lactic acid
Lactate is lactic acid, missing one proton. To be an acid, a substance must be able to donate a hydrogen ion; when lactic acid donates its proton, it becomes its conjugate base, or lactate.
adenylate kinase
a phosphotransferase enzyme that catalyzes the interconversion of adenine nucleotides (ATP, ADP, and AMP)
adenylate kinase reaction
2ADP ATP + AMP; particularly important because AMP is a product of the adenylate kinase (myokinase) reaction, a powerful stimulant of glycolysis
hexokinase
an enzyme that phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate of hexokinases, and glucose-6-phosphate is the most important product
phosphorus
chemical element with the symbol P and atomic number 15. Elemental phosphorus exists in two major forms, white phosphorus and red phosphorus, but because it is highly reactive, phosphorus is never found as a free element on Earth. It has a concentration in the Earth’s crust of about one gram per kilogram (compare copper at about 0.06 grams). In minerals, phosphorus generally occurs as phosphate. Phosphorus is essential for life. Phosphates (compounds containing the phosphate ion, PO43−) are a component of DNA, RNA, ATP, and phospholipids. Elemental phosphorus was first isolated from human urine, and bone ash was an important early phosphate source. Phosphate mines contain fossils because phosphate is present in the fossilized deposits of animal remains and excreta. Low phosphate levels are an important limit to growth in some aquatic systems. The vast majority of phosphorus compounds mined are consumed as fertilisers. Phosphate is needed to replace the phosphorus that plants remove from the soil, and its annual demand is rising nearly twice as fast as the growth of the human population. Other applications include organophosphorus compounds in detergents, pesticides, and nerve agents.
pyruvate
Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH3COCOO−, is a key intermediate in several metabolic pathways throughout the cell. Pyruvic acid can be made from glucose through glycolysis, converted back to carbohydrates (such as glucose) via gluconeogenesis, or to fatty acids through a reaction with acetyl-CoA. It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation. Pyruvic acid supplies energy to cells through the citric acid cycle (also known as the Krebs cycle) when oxygen is present (aerobic respiration), and alternatively ferments to produce lactate when oxygen is lacking (lactic acid).
allosteric
relating to or denoting the alteration of the activity of a protein through the binding of an effector molecule at a specific site.
allosteric activation
occurs when an “activator” binds with the enzyme and increases its turnover rate
allosteric inhibition
occurs when an end product binds to the regulatory enzyme and decreases its turnover rate and slows product formation
docosahexaenoic acid (DHA)
an omega-3 fatty acid. a primary structural component of the human brain, cerebral cortex, skin, and retina. can be synthesized from alpha-linolenic acid or obtained directly from maternal milk (breast milk), fish oil, or algae oil. fish sources: cooked salmon contain 500-1500 mg DHA and 300-1000 mg EPA per 100 grams. other sources: DHA include caviar (3400 mg per 100 grams), anchovies (1292 mg per 100 grams), mackerel (1195 mg per 100 grams), and cooked herring (1105 mg per 100 grams). brains from mammals are also a good direct source, with beef brain, for example, containing approximately 855 mg of DHA per 100 grams in a serving.
eicosapentaenoic acid (EPA)
an omega-3 fatty acid. obtained in the human diet by eating oily fish or fish oil, e.g. cod liver, herring, mackerel, salmon, menhaden and sardine, and various types of edible algae. also found in human breast milk. a precursor to docosahexaenoic acid (DHA). converted from ALA, but medical conditions like diabetes or certain allergies may significantly limit the human body’s capacity for metabolization of EPA from ALA.
beta oxidation
the catabolic process by which fatty acid molecules are broken down in the cytosol in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport chain. It is named as such because the beta carbon of the fatty acid undergoes oxidation to a carbonyl group.
calcium ATPase
Ca2+ ATPase (PMCA) is a transport protein in the plasma membrane of cells that serves to remove calcium (Ca2+) from the cell. it is vital for regulating the amount of Ca2+ within cells. uses hydrolysis of ATP.