ch1 Flashcards

(43 cards)

1
Q

Phases of the Menstrual Cycle

A

Menstruation
Follicular Phase (Early/Late)
Ovulation

Luteal Phase*

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2
Q

Progesterone highest?

A

Luteal phase

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3
Q

LH peak during _____ phase

A

during ovulation

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4
Q

Marks the first day of a new menstrual cycle

A

Menstruation: Discharge of bloody fluid containing endometrial and blood cells

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5
Q

How long does menstruation last?

A

typically 3-5 days

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6
Q

How does menstruation occur?

A

It is triggered by the decline in estrogen and progesterone(especially progesterone) from the last cycle

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7
Q

What causes endometrial tissue to die?

A

Vasoconstriction

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8
Q

How is endometrial tissue expelled out of the uterus?

A

uterine contractions

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9
Q

4 main hormones in the menstrual cycle

A

Follicle Stimulating Hormone (FSH)
Luteinising Hormone (LH)
Estrogen
Progesterone

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10
Q

2 Phases of the Menstrual Cycle

A
  1. Follicular Phase
  2. Luteal Phase
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11
Q

What is the Follicular phase?

A

When ovum is still in the follicle

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12
Q

How long is a typical menstrual cycle?

A

28 Days

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13
Q

How long does Luteal Phase last?

A

ALWAYS 14 days

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14
Q

How long does Follicular Phase last?

A

varies from 8-14 days. It is the reason for the variation in the duration of menstrual cycle

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15
Q

What is the Luteal phase?

A

when ovum is released from the follicle and into the fallopian tube

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16
Q

What is responsible for regulating a large number of hormones?

A

Pituitary glands

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17
Q

Early Follicular Phase

A

Hypothalamus releases Gonadotrophin Releasing Hormone (GnRH) which releases gonadotrophins (FSH and LH) from the ANTERIOR pituitary gland

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18
Q

Main job of FSH

A

Stimulate the development of the follicles

19
Q

Main job of LH

A

To cause ovulation

20
Q

Primordial follicles

A

immature eggs in the ovaries. about 200,000 in each ovaries but not all are viable eggs

21
Q

What secretes estrogen?

A

Granulosa cells around the FSH-stimulated follicles

22
Q

Estrogen

A

Steroid sex hormones that promote female secondary characteristics. Also stimulates the development of endometrium.

Also causes cervix mucus to become thinner to allow faster sperm travel

23
Q

What causes a negative feedback to the pituitary glands and the hypothalamus to suppress the release of LH and FSH?

24
Q

What happens when there is an INCREASE in LH?

A

Causes the follicles to reach the surface of ovary and release the ovum (unfertilized eggs)

25
When does ovulation occur?
at day 14 of the menstrual cycle
26
What secretes high levels of progesterone?
Corpus luteum after ovulation
27
What does progesterone do?
Thicken and maintain endometrial lining Thicken cervical mucus Causes a rise in body temperature
28
What secretes Human Gonadotrophin (HCG)?
Fertilized embryo
29
What keeps a corpus luteum alive in a fertilized embryo?
Human Gonadotrophin (HCG)
30
Matured dominant follicles that are stimulated by FSH?
Graafian follicle
31
blastocyst
pre-embryo
32
Factors Affecting Timing of Menarche
Age of maternal menarche Socioeconomic status (-) Body mass index (-) Exposure to endocrine-disrupting chemicals
33
Factors Affecting Timing of Menopause
Age of maternal menopause Irregular cycles (-) African American race (-) Psychosocial stress (-) Smoking (-) Oral contraceptive use: conflicting
34
Signs of ovulation
Lots of “egg-white” cervical mucus followed by sudden drying up Increase in libido leading up to ovulation Ovarian pain during ovulation (also known as “mittelschmertz”) Mid-cycle increase in basal body temperature
35
How many % of menstrual cycles are anovulatory?
about 10%
36
synthetic estrogen and progesterone
progestogen
37
How does birth control prevent ovulation?
Estrogen and progesterone feed back in the HPG axis to prevent FSH and LH release
38
prevents the production of fertile cervical mucus
progestogen
39
How do IUDs work?
The presence of an IUD in the uterus creates an inflammatory reaction that prevents fertilization of the ovum by sperm
40
release a progestogen, which prevents fertile cervical mucus and prevents thickening of the uterine lining
Hormonal IUDs
41
Why aren’t my periods regular?
Possible causes of menstrual irregularity Stress can cause occasional irregularity Thyroid dysfunction Excessive exercise Eating disorders Uncontrolled diabetes Primary ovarian insufficiency Most common: polycystic ovarian syndrome
41
What percent of women are affected by Polycystic Ovarian Syndrome (PCOS)
5-10% of women
42
Symptoms of PCOS
2 out of 3 of the following criteria: Menstrual irregularity Signs of elevated testosterone (e.g. acne, excess body hair, hair loss) Polycystic ovaries (via ultrasound) Responds well to low glycemic index diet & exercise