Ch11 - Animal Procurement & Quarantine

Question 1

Which federal mandate provided descriptions of shipping crate sizes and configurations for hamsters?

Answer 1

Animal Welfare Regulations

Question 2

What method of animal identification do most institutions use for animals arriving at a facility?

Answer 2

Cage cards

Question 3

What species of laboratory animal does NOT have specific identification requirements based on their USDA number?

Answer 3

Horses

Question 4

What approval is needed before ordering animals?

Answer 4

An approved IACUC protocol

Question 5

What type of air pressure is maintained in a quarantine room?

Answer 5

Negative (air flows in, preventing inside contaminants from flowing out)

Question 6

What is a sign of heat stress in rodents?

Answer 6

Excessive salivation

Question 7

What is the microbiological status of animals that carry an unknown, and uncontrolled variety and number of organisms?

Answer 7

Conventional

Question 8

What source of animals is MOST likely to harbor disease-causing agents?

Answer 8

A dealer who provides wild caught animals

Question 9

What are 3 steps that a technician should do to verify and begin processing the contents of a new shipment of animals?

Answer 9

1. assess and document that cleanliness of the transporting vehicle
2. compare the original animal order with the shipping label info
3. report container damage to the supervisor and transportation company

Question 10

What is the class of dealer who breeds their own animals for sale to research facilities?

Answer 10

Class A dealer

Question 11

What class of dealer obtains animals from random sources, conditions them, and sells them to research facilities?

Answer 11

Class B dealer

Question 12

Name 3 work practices that can be used to minimize the risk of transmitting disease between animals in quarantine and those in established clean colonies.

Answer 12

• do this room last (after clean rooms)
• dispose of PPE after exiting room
• work done by trained staff

Question 13

List 4 items of general information about the animals that should be provided on an animal procurement form.

Answer 13

Age, sex, species, strain or stock

Question 14

What term refers to the types of organisms that an animal is carrying?

Answer 14

Microbial status

Question 15

What is the term for the separation of newly received rodents from those already in the facility until the microbial status of the newly received animals has been determined? What type of pressure is this room under?

Answer 15

Quarantine; negative

Question 16

Animal housing for which the primary goal is keeping an experimental infectious agents restricted within the population is called _________.

Answer 16

Containment

Question 17

Why do health documents from the vendor accompanying an animal shipment NOT exempt the animals from quarantine?

Answer 17

The animals may have been exposed to infectious agents while in transit

Question 18

If an animal is exposed to a pathogen while in transit to a research facility, typically how long is it before the animal will test positive for the pathogen?

Answer 18

2-3 weeks

Question 19

What is the microbial status of lab animals that harbor no detectable bacteria, viruses or other microorganisms; also known as axenic.

Answer 19

Germfree

Question 20

What is the microbial status of lab animals that are nearly devoid of microorganisms but have been provided with a small number of known bacteria?

Answer 20

Gnotobiotic or defined flora

Question 21

What is the microbial status of lab animals that are carefully monitored to be sure they do not harbor certain pathogenic organisms?

Answer 21

Specific pathogen-free

Question 22

Most animals need an acclimation and conditioning time period of _______, however NHPs need _______.

Answer 22

72 hours; 14 days

Question 23

A period during which newly received animals that are underweight or in poor health are treated to improve their health and body condition is called ______.

Answer 23

Conditioning period

Question 24

The time for animals to recover from transport and to adjust to new surroundings is called ________.

Answer 24

acclimation period

Question 25

List 3 things that determine the period of time needed for an animal's acclimation and conditioning period upon arrival.

Answer 25

- the species - mode of transportation - intended use

Question 26

List 2 documents the technician should compare to confirm that the animals are received are the ones ordered.

Answer 26

purchase orders and shipping invoices

Question 27

What documents typically contain the species or strain of the animal, the investigator's name, protocol number, contact info, the source of the animal, and may contain a barcode?

Answer 27

Cage cards

Question 28

What procedure should an animal technician perform before disposing of animal shipping containers?

Answer 28

Double check the containers for any remaining animals

Question 29

The Animal Welfare Regulations specify the standards under which covered animals may be transported (ex: it specifies some characteristics of the materials with which shipping cages, boxes or cartons may be made). List 3 other topics covered in the transportation-related regulations of the AWR

Answer 29

Acceptable temp ranges, ventilation, and space; sufficient room to make normal postural movements; how often animals should receive food and water during shipment; how often animals should be observed

Question 30

Describe why wild caught animals should be housed away from the rest of the animals in the facility.

Answer 30

Wild caught animals have an unknown health status, and they are more likely to carry parasites and pathogens than animals purchased from a dealer