Chap 2 Eli PI Safety

Question 1

Which of the following adverse reactions is not covered in the boxed warning for ELITEK®?
A. Hemolysis
B. Hypophosphatemia
C. Methemoglobinemia
D. Interference with uric acid measurements

Answer 1

B. Hypophosphatemia

Question 2

True or false. ELITEK® is contraindicated in individuals deficient in glucose-6-phosphate dehydrogenase.
____ True ____ False

Answer 2

True

Question 3

Consider the adverse events reported from Studies 1-3 and the uncontrolled safety trial involving 265 pediatric and 82 adult patients. What was the most commonly reported adverse event, seen in 50% of the patients?
A. Fever
B. Headache 
C. Nausea 
D. Vomiting

Answer 3

D. Vomiting

Question 4

Which of the following does not correctly describe how to avoid uric acid degradation in patients receiving ELITEK®?
A. Blood collection tubes should be pre-chilled prior to collection.
B. Immediately immerse plasma samples in an ice water bath.
C. Prepare samples in a pre-chilled centrifuge.
D. Analyze samples for uric acid within 24 hours of collection.

Answer 4

D. Analyze samples for uric acid within 24 hours of collection.

Question 5

True or false. It is not known whether rasburicase is excreted in human milk.
____ True ____ False

Answer 5

True