CHAP 5 MIDTERMS

Question 1

a general term for agents that bind to cholinoceptors (muscarinic or nicotinic) and prevent the effects of acetylcholine (ACh) and other cholinergic agonists

Answer 1

Cholinoceptor Antagonists

Question 2

also known as antimuscarinic agents or parasympatholytics selective blockers of muscarinic receptors

Answer 2

Anticholinergic Agents

Question 3

• the prototype of antimuscarinic drugs

found in the plant Atropa belladona (deadly nightshade), and Datura stramonium (Jimsonweed/ Jamestown weed; sacred Datura or thorn apple)

Answer 3

Atropine (Hyoscyamine)

Question 4

MOA OF ATROPINE

Answer 4

• Atropine causes reversible (surmountable) blockade of cholinomimetic actions at muscarinic receptors
• actions last about 4 hours except when placed topically in the eye, where the action may last for days