Chapter 03: Erectile Dysfunction Flashcards Preview

PSIO 469 (reproductive) > Chapter 03: Erectile Dysfunction > Flashcards

Flashcards in Chapter 03: Erectile Dysfunction Deck (14):
1

What is a disorder that is due to depression, anxiety and pyschological stress?

Psychogenic

2

What is the four types Organic causes of ED

Neruogenic
Hormonal
Vasculogenic
Drug Induced

3

What is the brand name for the following drugs:
Sildenafil
Vardenafil
Tadalafil

Viagra
Levitra
Cialis

4

Where is smooth muscle NOT loacted:
A. Blood vessels
B: Penis
C. Heart
D. Eyes
E. Walls of hollow organs in digestive, reproductive and urinary tracts

C.

5

An increase in ___________ leads to binding of ______ to _____ and ______cycling resulting in muscle_______

Word Bank:
Myosin
Actin
Cross bridge
Cytoplasmic Calcium
Contraction

C.C; M; A; CB; C

6

The regulatory light chain is phosphorlyated by _________

MLCK (Myosin light chain kinase)

7

What activates MLCK?

Calmodulin Ca++ complex

8

When cytoplasmic Ca++ is (high/low), Ca++ forms a complex with calmodulin which (activates/deactivates) MLCK, which causes smooth muscle (contraction/relaxation). When cytoplasmic Ca++ is. (High/Low), myosin phosphotase (phosphorylates/dephoshphorylates) regulatory light chain which causes smooth muscle (contraction/relaxation)

High; activates; contraction
Low; dephoshorylates; relaxation

9

PDE5 block _____ of____ to_______and lead to lowered cytoplasmic Ca++ and lead to relaxation

Hydrolysis; cGMP to 5’-GMP

10

PD5E afftects which tissues?

Corpus cavernosum, vascular smooth muscle and platelets

11

Why are nitrates bad for people taking PDE5 inhibitors?

Nitrates are vasodialators and can lead to servere drop in blood pressure

12

What is priapsim and what treatments can be done for men who have it?

Priapism is a condition where erection becomes very painful and persistent (prolonged erection).
Treatments include injection of phenylephrine into the smooth muscle or surgical drainage

13

Where must the Alprostadil be injected into if not inseting it into the urethra and why must you not exceed the maximum dosage (3x per week)?

Into the corpus cavernosa (chemical response more than neural)
Too many dosages can cause peyronie’s disease

14

What is Peyronie’s disease?

A form of ED that causes a bend in the penis which makes erections painful. This involves the corpora cavernosa