chapter 1

Question 1

what is the meaning of haemaoiesis

Answer 1

process of formation of blood

Question 2

where does blood formation in adults

Answer 2

bone marrow. midline flex

Question 3

what are the key elements

Answer 3

1. bone marrow microenviro
2. cytokines
3. nutrients
4. hormones

Question 4

hormones that was made from liver for haempoesis

Answer 4

thrombopoetin ; kidney-arythropoeitin

Question 5

what is the regulator for erythropoiesis

Answer 5

erythropoeitein

Question 6

iron dependence

Answer 6

3-4 days

Question 7

ERYHTROPOESIS

Answer 7

stem cells- bfu-cfu

Question 8

monocyte berenti sampai mana je?

Answer 8

sampai blood je,

Question 9

monocyte can differentiate jadi apa

Answer 9

macrophages foun in tissue takes several months or year before ded

Question 10

granulocytes

Answer 10

6-10 days in bone marrow n 6-10 hrs in blood

Question 11

lymphopoeisis

Answer 11

form bone marrow, pergi thrombin (t cells mature kat situ) nk cells and b cells

Question 12

thrombopoeisis

Answer 12

mk cells

Question 13

duration of maturation of mk cells

Answer 13

10days

Question 14

mk cells jadi…..

Answer 14

platlets

Question 15

buffer contains

Answer 15

platlets n wbc

Question 16

platlets

Answer 16

anucleate cells, discoid, 7-10 days,

Question 17

platlets in volves in

Answer 17

primary haemostasis

Question 18

end product or formation of…..

Answer 18

unstable paletlet plug kalau injury

Question 19

our body benefits from platlets

Answer 19

during endothelial injury

Question 20

majority clotting fac synthesised in

Answer 20

liver

Question 21

coagulation composed of

Answer 21

clotting fac

Question 22

does clooting fac it in active or inactive form

Answer 22

inactive form in plasma bcs the blood will keep coagulate kalau dalam active form

Question 23

bila clotting fac active?

Answer 23

when injury

Question 24

what major role in secondary haemostasis?

Answer 24

coagulation

Question 25

end product coagulation

Answer 25

stable fibrin/ plug clot

Question 26

coagulation with shortest halflife

Answer 26

5hrs coagulations fac 7 (vii)

Question 27

nak coagulate darah dalam lab kena ada

Answer 27

phospholipid n calcium

Question 28

phases of secondary haemostasis

Answer 28

1. initiation | 2. amplification

Question 29

active form of clotting fac

Answer 29

i=enzyme serine protease

Question 30

final phase of haemostasis

Answer 30

fibrinolysis

Question 31

fx of fibrinolysis

Answer 31

to lysis the fibrin clot afterinjury repaired

Question 32

what is the keyplayer in fibrinolysis

Answer 32

plasminogen (inactive form) beta globulin proenzyme

Question 33

ACTIVE FORM OF PLASMINOGEN

Answer 33

plasmin after converted by tpa, clotting fac and kallikrein

Question 34

end product of fibrinolysis

Answer 34

1. fibrinogen degradation product (fdp) | 2. d dimer

Question 35

fx of plasmin

Answer 35

digest fibrinogen, fibrin clotting fac and protein

Question 36

tpa diactivekan/ kerja bila kena trigger dengan

Answer 36

PAI

Question 37

fx of TAFI thrombin activated fibrinolysis inhibitor

Answer 37

inhibit fibrinolysis process

Question 38

where the fdp went?

Answer 38

reticuloendothelial system pergi kidney or liver