chapter 1 Flashcards

1
Q

Define Drug

A

any chemical that alters an organisms functions or processes

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2
Q

Define pharmacoology

A

the study of drugs (origin, properties, and interacting)

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3
Q

Define Pharmacy

A

preparation and dispensing of drugs

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4
Q

Define therapeutics

A

art of treating disease with drugs

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5
Q

Define toxicology

A

study of toxic substances an their pharmacological actions, including antidotes and poison control

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6
Q

Define pharmacognosy

A

identification of sources of drugs

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7
Q

Today the most common source of drugs is?

A

chemical synthesis but plant, animals, and minerals have often contributed the prototype of the active ingredient

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8
Q

Naturally occurring drugs date back to when?

A

Egyptian papyrus records, to the ancient Chinese and Central American civilizations and is still seen in remote regions of modern America, such as Appalachia.

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9
Q

Animal is a source of drug, name what is under its classification.

A
  • thyroid hormone
  • insulin
  • pancreatic domase
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10
Q

plant is a source of drugs, name what is under its classification.

A
  • khellin (ammi visnaga)
  • Atropine (belladonna alkaloid)
  • Digitalis (fox glove)
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11
Q

Mineral is a source of drugs, name what is in its classification.

A
  • Copper sulfate
  • magnesium sulfate
  • mineral oil
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12
Q

Drug approval in the US is long, costly, and complex. In thee 1980’s it took 13-15 years and 350 million dollars (chemical trials to FDA approval. A more recent study showed?

A

900 million dollar in today’s market (research, development, pre and post clinical trials)

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13
Q

There is how many phases in drug approval?

A

3 phases

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14
Q

Define Mutagenicity

A

mutation in the gene

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15
Q

Define Teratogenicity.

A

Changes in the developing embryo

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16
Q

Define Carcinogenicity

A

increase risk of cancer

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17
Q

What is phase 1?

A

Investigated in small groups of individuals with the disease the drug is intended to treat

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18
Q

What is phase 2?

A

Investigated as a treatment for a small number of individuals with the disease the drug is intended to treat

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19
Q

What is phase 3?

A

investigated in large, multi center studies to establish safety and efficacy

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20
Q

Naming drugs: What is the Chemical name?

A

The name indicating the drug’s chemical structure

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21
Q

Naming drugs: What is the code name?

A

A name assigned by a manufacturer to an experimental chemical that shows potential as a drug
-numerical or alphanumerical

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22
Q

Naming Drugs: what is the generic name (aka nonproprietary)?

A

name assigned by the United States adopted name (USAN) Council when a chemical appears to have therapeutic uses and the manufacturer wishes to market the drug
-name i base loosely on the chemical structure of the drug

23
Q

Naming drugs: What is the official name?

A

in the event an experimental drug becomes fully approved for general use, the generic name becomes its official name.

24
Q

Naming drugs: What does the Trade Name (aka proprietary nme) mean?

A

brand name given by a particular manufacturer

25
aa
of each
26
bid
twice a day
27
c
with
28
cc
cubic centimeters
29
Elix
elixir
30
mL
milliliter
31
npo
nothing by mouth
32
p
after
33
po
by mouth
34
prn
as needed
35
q
every
36
qh
every hour
37
qid
four times a day
38
qd
every day
39
qs
much as needed
40
qs
much as needed
41
s
without
42
stat
immediately
43
tid
three times a day
44
L
liter
45
IV
intavenous
46
IM
intramuscular
47
Rx
take
48
What is a prescription?
a written order for a drug, with specific instruction
49
List the part of a prescription
- patients name, address, and written date - Rx means "recipe" or "take thou". Directs the pharmacist to take the drug listed and prepare the medication (superscription) - Inscription lists the name and quantity of the drug - Directions flor preparation when applicable - Sig (signa) "write" directions to the patient - Name of prescriber
50
A physician can indicate to the pharmacist that generic substitution is permitted. In this case the pharmacist may provide any manufacturers version of the drug.
Generic is lower in cost because the generic manufacturer has not invested the time and money in developing the original drug.
51
Drugs that are available to the general population without a prescription. The strength and amount maybe less than with a prescription. What are the increased risks?
- the effects are not understood | - large quantities
52
A central group of respiratory drugs are given by inhaled aerosol for the direct treatment of the upper and lower airway in pulmonary disease. what are they?
- Adrenergic agents - Anticholinergic agents - mucoactive agents - corticosteroids - anti-asthmatic agents - antiinfective agents - exogenous sufactants -
53
Aerosolized agents given by inhalation provide local topical treatment of the respiratory tract. What are the following advantages?
- smaller doses - fewer side effects - rapid onset - targeted delivery - painless, relatively safe and convenient
54
What are the related drug groups in respiratory care?
- antiinfective agents - neuromuscular blocking agents - central nervous system agents - anti-arrhythmic agents - antihypertensive and antianginal agents - anticoagulant and thrombolytic agents - diuretics agents