Chapter 1: red blood cell and platelet preservation : Historical perspectives and current traits

Question 1

• 1492
• 1st blood transfusion
• 1st human-to-human blood transfusion
• suffered from a condition known as (HEMOPHILIA)
• then because of the different donors he died

Answer 1

Pope Innocent VII

Question 2

• no man/ mankind has never attempted to do blood transfusion

Answer 2

1492- 1900

Question 3

• Braxton hicks
• SODIUM PHOSPHATE as anticoagulant
• sodium phosphate is not safe

Answer 3

1869

Question 4

• Karl landsteiner
• he discover the ABO blood groups
• golden year
• discovery of blood type
• FATHER OF IMMUNOHEMATOLOGY

Answer 4

1901

Question 5

• Von decastello & Sturli
• 4th blood group which is AB

Answer 5

1902

Question 6

• Hustin
• reported the use of SODIUM CITRATE as anticoagulant
• citrate is the safest anticoagulant
• sodium citrate prevents clotting of clothing but not a preservative

Answer 6

1914

Question 7

• Lewisohn
• determined the minimal amount of citrate can provide an anticoagulant of blood

Answer 7

1915

Question 8

• Rous & Turner
• Citrate dextrose Solution

Answer 8

1916

Question 9

• Loutit & Mollison
• Formula for acid citrate dextrose (ACD)

Answer 9

1943

Question 10

• Gibson
• Citrate Phosphate Dextrose (CPD) as anticoagulant preservative solution

Answer 10

1957

Question 11

• Dr. Charles Drew
• FATHER OF RED CROSS
• appointed as 1st director of the American Red Cross blood bank at Presbyterian hospital

PHILIPPINE
- Aurora Aragon Quezon
- 1st lady of the country
- established the Philippines Red Cross

Answer 11

1941

Question 12

• William harvey
• discovered the blood/ circulation

Answer 12

1628

Question 13

• Jan swammerdan
• observed & described RBC

Answer 13

1658

Question 14

• Richard lower
• 1st recorded successful blood transfusion in dogs

Answer 14

1665

Question 15

• Jean baptiste dennis & Richard lower
• blood transfusion from Sheep to humans

Answer 15

1667

Question 16

• James blundell
• 1st successful transfusion of human blood (pregnant px w/ hemorrhage, gets blood from husband)

Answer 16

1818

Question 17

• Us physicians transfuse milk from cows, goats & humans
• to not die due to Hypovolemia

Answer 17

1873 - 1880

Question 18

• Saline infusion replaces milk as substitute blood due to increased frequency of adverse reaction to milk

Answer 18

1884

Question 19

• Ludwig Hektoen
• Crossmatching between donors and px (introduced)

Answer 19

1907

Question 20

• Reuben ottenberg
• 1st to perform blood transfusion using blood typing and crossmatching

Answer 20

1907

Question 21

• Roger lee
• group O as universal blood donor &
• group AB as universal blood recipient

RBC
O - universal blood donor
AB - universal blood recipient

PLASMA
O - universal recipient
AB -universal donor

Answer 21

1912

Question 22

• Long term anticoagulant

Answer 22

1914

Question 23

• Isodor radvin
• treated victims of the pearl harbor attack with Cohn’s albumin for shock

Answer 23

1941

Question 24

• Coombs, Mourant & Race
• use of AHG to identify “incomplete” antibodies

Answer 24

1945