Chapter 15 Flashcards

(41 cards)

1
Q

Metabolism/ Intermediary metabolism

A
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2
Q

Metabolomics

A

is the study of metabolites and the chemical reactions they undergo during physiological and pathological conditions.

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3
Q

Metabolic Pathways

A

Fuels are degraded and large molecules are constructed step by step in a series of linked reactions called

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4
Q

adenosine triphosphate (ATP)

A

links energy-releasing pathways with energy-requiring pathways.

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5
Q

fuels powers the formation of ATP

A

The oxidation of carbon

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6
Q

Catabolism (definition)

A

breaking down big, complex molecules into smaller ones. Transforming fuels into cellular energy

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7
Q

what happens during catabolism

A

Fuel (carbs, fats—–(catabolism)—–> CO2 + H20 + useful energy

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8
Q

Anabolism (deinition)

A

building molecules from smaller ones. For example, synthesizing glucose, fats or DNA

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9
Q

Anabolism (equation) what happens during it

A

Useful energy + simple precursors—-(anabolism)—> complex molecules

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10
Q

Amphibolic

A

pathways that are both catabolism and anabolism

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11
Q

What are thermodynamically favored reactions?

A

When Delta G is negative, a spontaneous reaction.

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12
Q

ATP is composed of

A

adenine, a ribose, and a triphosphate unit

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13
Q

ATP will break down in to

A

ADP and Pi or to AMP and PPi

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14
Q

ATP hydrolysis is

A

EXERGONIC

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15
Q

Phosphorylation of nucleoside monophosphates is catalyzed by

A

a family of nucleoside monophosphate kinases.

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16
Q

exogenic vs

A
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17
Q

what 2 pathways must a thermodynamic equation satisfy

A

The individual reactions must be specific

The entire set of reactions that constitute the pathway must be thermodynamically favored

18
Q

what kind of reaction happens when delta G is negative

A

Spontaneous reaction

19
Q

ATP is composed of

A

adenine, a ribose, and a triphosphate unit

20
Q

triphosphate unit contains__phosphoanhydride bonds

21
Q

ATP will break down to

A

ADP and Pi or to AMP and PPi

22
Q

How is a Phosphorylation of nucleoside monophosphates is catalyzed by ___

A

a family of nucleoside monophosphate kinases.

23
Q

is ATP hydrolysis exergonic

24
Q

Phosphorylation

25
kinase
26
Energy from foodstuffs is extracted in three stages:
27
pyridine nucleotides (NAD+)
28
flavins (FAD).
29
thermodynamically unfavorable
30
what kind of reaction when DELTA G is negative
spontaneous reaction
31
spontaneous reaction
32
why is atp energy rich
bc of its triphosphate which has 2 phosphohydride
33
exergonic
releases energy
34
What makes ATP an efficient phosphoryl-group donor?
Four factors are important: resonance stabilization, electrostatic repulsion, increase in entropy and stabilization due to hydration.
35
resonance stabalization
36
electrostatic repulsion
37
entropy
38
stabilization (due to hydration)
39
Recurring Motifs
40
phosphoryl transfer from ATP is an ________ process
exergonic
41
substrate