Chapter 18 Flashcards
(20 cards)
RBCs have __ nucleus.
No (anucleate)
Erythrocytes contain which 2 proteins?
hemoglobin (Hb) and spectrin (flexibility)
In erythrocytes, Protein globin contain how many chains?
two alpha and two beta chains
_____ pigment bonded to each globin chain.
Heme
Iron atom in each heme can bind to one ___
O 2 molecule
Each Hb molecule can transport ______.
four O 2 molecule
O2 loading in lungs produces?
oxyhemoglobin (ruby red)
O2 unloading in tissues produces?
deoxyhemoglobin or reduced hemoglobin
(dark red)
CO2 loading in tissues produce what?
20% of CO2 in blood binds to Hb à
carbaminohemoglobin
Hormone Erythropoietin (EPO)
form of doping, released by kidneys (from liver) in response to hypoxia
WBC Neutrophils (Granulocyte) function
Attack bacteria by eating and digesting them with enzymes
% of neutrophils in WBC
Most abundant WBC (50-70%)
What do neutrophils contain?
peroxidases, hydrolytic enzymes, and defensins (antibiotic proteins)
WBC Eosinophils (Granulocyte) functions?
Lead the body’s counterattack
against parasitic worms, and Lessen the severity of allergies
by phagocytizing immune
complexes
% of eosinophils in WBC
1-4% of WBC
WBC Basophils (Granulocyte)
Have large, purplish-black
(basophilic) granules that
contain histamine
Histamine
inflammatory chemical that acts as
a vasodilator and attracts other
WBCs to inflamed sites
vasodilation 17
% of basophils in WBC
Rarest WBC (0.5% of total)
WBC Monocyte (arganulocyte)
largest WBC with large kidney
or Pac Man nuclei
% of monocytes in WBC
3-8% of WBC
