chapter 19: gene tech pt2 gene tech in medicine - gene therapy - gene tech in agriculture.

Question 1

what are the advantages of gene tech in ?

Answer 1

• simple nutritional requirements
• large volumes of product
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• can be carried out in anywhere around the world

Question 2

what are the disadvantages of gene tech in medicine ?

Answer 2

• bacteria do not modify their proteins in the same way eukaryotic cells do
• (ethical issue) don’t extract proteins from animals

Question 3

what are the recombinant human proteins to treat humans ?

Answer 3

insulin, factor VIII, (ADA) adenosine deaminase

Question 4

what is factor VIII used to treat ? how is it extracted ?

Answer 4

factor VIII is used to treat hemophilia
- factor VIII is produced by hamster kidney and ovarian cells (cells constantly produce factor VIII which is extracted and purified)

Question 5

what are the advantages of using GMOd factor VIII ?

Answer 5

• ppl with hemophilia needs regular injections of factor VIII
• beofre GMOd factor VIII, factor VIII came from donated blood, which carried risks of infection like HIV- - recombinant factor VIII avoids such problems

Question 6

what is ADA used to treat ? how is it produced ? When is it - ppl with hemophilia needs regular injections of factor VIII
- beofre GMOd factor VIII, factor VIII came from donated blood, which carried risks of infection like HIV- - recombinant factor VIII avoids such problems

Answer 6

• ADA is used to treat SCID
• made by genetically modified insect larva (cabbage looper moth caterpillar)
• this enzyme is administered to patients while they wait for gene therapy or when tis not possible.

Question 7

what is genetic screening ?

Answer 7

Genetic screening is the analysis of a person’s DNA to check for the presence of a particular allele.