Chapter 2 Flashcards
(26 cards)
what 3 elements make up a chromosome
centromere, pair of telomeres, and origin of replication
centromere
constricted region on the chromosome, serves as attachment point for spindle microtubules
what are four types of chromosome?
metacentric, submetacentric, acrocentric, and telocentric
what are telomeres
specific DNA sequence located at the tip of chromosome and protect and stabilize chromosome ends and stabilize it
origin of replication
sites where DNA synthesis begins
what happens to begin cell division?
chromosomes replicates and make a copy of itself (sister chromatids) and hold together at chromosome
what are sister chromatids?
identical copies made before cell division and contains one molecule of DNA
Interphase
period between cell divisions in which cell grows, develops, and functions. DNA is made, RNA and proteins are being produced
Purpose of G0 phase
stable and nondividing period
G1 phase
cell grows and proteins for cell division are being synthesized
G1S phase
Holds G1 until cell has all the enzymes and proteins necessary for replication; after, it is ready to divide
G2 phase
checkpoint to make sure all of DNA is replicated
M (mitotic) phase
cell division occurs; includes mitosis, process of nuclear division and cytokinesis, complete set of genetic information
Prophase
- chromosomes condense and become compact
- mitotic spindle forms
Prometaphase
-nuclear membrane breaks down
- spindle microtubules enter the region and are composed of subunits of a protein called tubulin
Metaphase
-Chromosomes line themselves up in the metaphase plate between two centromeres
- centrioles are at opposite ends of the pole, microtubules meeting in the middle of the cell
Anaphase
- connection between two sister and chromatid breaks down and the sister chromatids separate
-chromosomes move toward end of pole - molecular motor proteins degrade tubulin molecules and force chromosomes toward spindle poles
Telophase
- after sister chromatids have separated, they are both separate chromosomes
- marked by the arrival of the chromosome at the spindle poles
- nuclear membrane reforms around each set of chromosomes, producing two separate nucleus in the cell
Cytokinesis
cytoplasm divides, cell wall forms in plant cell
Chromosome
single sister chromatids
what type of chromosomes do humans have?
Humans have diploid (2n), and they come in matched sets (homologous chromosomes); 46 chromosomes organized into 23 chromosomes
What is the product of the cell cycle?
- produces two cells that contain the same genetic material and identical with each other and with their parent cell
- creates an exact copy of each DNA molecule; two genetically identical sister chromatids
- amount of DNA doubles in the S phase
How to determine the # of chromosomes?
count the number of functional centromeres
how do you know if sister chromatids are present?
chromosome has replicated and the number of DNA molecules is twice the number of chromosomes