Chapter 2 Flashcards

(26 cards)

1
Q

what 3 elements make up a chromosome

A

centromere, pair of telomeres, and origin of replication

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2
Q

centromere

A

constricted region on the chromosome, serves as attachment point for spindle microtubules

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3
Q

what are four types of chromosome?

A

metacentric, submetacentric, acrocentric, and telocentric

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4
Q

what are telomeres

A

specific DNA sequence located at the tip of chromosome and protect and stabilize chromosome ends and stabilize it

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5
Q

origin of replication

A

sites where DNA synthesis begins

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6
Q

what happens to begin cell division?

A

chromosomes replicates and make a copy of itself (sister chromatids) and hold together at chromosome

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7
Q

what are sister chromatids?

A

identical copies made before cell division and contains one molecule of DNA

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8
Q

Interphase

A

period between cell divisions in which cell grows, develops, and functions. DNA is made, RNA and proteins are being produced

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9
Q

Purpose of G0 phase

A

stable and nondividing period

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10
Q

G1 phase

A

cell grows and proteins for cell division are being synthesized

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11
Q

G1S phase

A

Holds G1 until cell has all the enzymes and proteins necessary for replication; after, it is ready to divide

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12
Q

G2 phase

A

checkpoint to make sure all of DNA is replicated

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13
Q

M (mitotic) phase

A

cell division occurs; includes mitosis, process of nuclear division and cytokinesis, complete set of genetic information

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14
Q

Prophase

A
  • chromosomes condense and become compact
  • mitotic spindle forms
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15
Q

Prometaphase

A

-nuclear membrane breaks down
- spindle microtubules enter the region and are composed of subunits of a protein called tubulin

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16
Q

Metaphase

A

-Chromosomes line themselves up in the metaphase plate between two centromeres
- centrioles are at opposite ends of the pole, microtubules meeting in the middle of the cell

17
Q

Anaphase

A
  • connection between two sister and chromatid breaks down and the sister chromatids separate
    -chromosomes move toward end of pole
  • molecular motor proteins degrade tubulin molecules and force chromosomes toward spindle poles
18
Q

Telophase

A
  • after sister chromatids have separated, they are both separate chromosomes
  • marked by the arrival of the chromosome at the spindle poles
  • nuclear membrane reforms around each set of chromosomes, producing two separate nucleus in the cell
19
Q

Cytokinesis

A

cytoplasm divides, cell wall forms in plant cell

20
Q

Chromosome

A

single sister chromatids

21
Q

what type of chromosomes do humans have?

A

Humans have diploid (2n), and they come in matched sets (homologous chromosomes); 46 chromosomes organized into 23 chromosomes

22
Q

What is the product of the cell cycle?

A
  • produces two cells that contain the same genetic material and identical with each other and with their parent cell
  • creates an exact copy of each DNA molecule; two genetically identical sister chromatids
  • amount of DNA doubles in the S phase
23
Q

How to determine the # of chromosomes?

A

count the number of functional centromeres

24
Q

how do you know if sister chromatids are present?

A

chromosome has replicated and the number of DNA molecules is twice the number of chromosomes

25
What happens between the sister chromatids and the chromosomes during anaphase?
Sister chromatids separate and each has its own centromere but after cytokinesis the 8 chromosomes are distributed equally between two daughter cells, so they each contain 4 chromosomes
26
what controls the separation of chromatics/chromosomes in mitosis and meiosis?
cohesion, a protein that holds sister chromatids together during the early part of mitosis 1 (glue) - in anaphase II, the chromatids can separate because it isn't protected, thus breaks down and separates in anaphase II