Chapter 2 Cognitive Psychology Flashcards

(46 cards)

1
Q

Neuron

A

Neurons are the basic unit of the brain and the nervous system.
The brain contains approximately 80-100 billion neurons.
During pregnancy, about 250,000 neurons are generated every minute (Ackerman, 1992).
There are an estimated 10-100 trillion connections (synapses) between these neurons.

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2
Q

Components of a Neuron

A

Cell Body: Maintains the neuron’s health, including nutrition and metabolism.

Dendrites: Receive electrochemical signals (information) from other neurons.

Axons: Transmit electrochemical signals (information) to other neurons

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3
Q

Neurons and Information Processing:

A

Neurons handle all information processing.
Input: Information from senses like vision, hearing, smell, taste, and touch.
Afferent neurons: Carry sensory information to the Central Nervous System (CNS).
Motor Output: Actions like movement and speech.
Efferent neurons: Transmit motor commands from the CNS to muscles.
Processing/Storage/Analysis: Happens in the brain, mainly using interneurons.

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4
Q

Neural Communication:

A

Neurons communicate despite not physically touching; they have gaps called synapses.
Neurons produce electrical signals called action potentials.
Communication between neurons occurs through chemical signals known as neurotransmitters.
Thus, neural communication is fundamentally electrochemical in nature.

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5
Q

Action Potential:

A

Neurons have a resting potential of around -70mV (millivolts) compared to the outside.
1 mV is equal to 1/1000 of a volt.
When a neuron’s receptor is stimulated, it depolarizes to around +40 mV compared to the outside.
After firing a signal, the neuron returns to its resting potential through repolarization.

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6
Q

Action potential, Electrical Activity in Neurons:

A

Electrical Activity in Neurons:

Resting Potential: Neuron is at its baseline, around -70mV.
Depolarization: Neuron becomes more positive (e.g., +40mV) during stimulation.
Repolarization: Neuron returns to its resting potential after firing.
Return to Resting Potential: The neuron settles back to its normal -70mV.
Action Potentials (AP): Each AP lasts about 1 millisecond (1/1000 of a second).
Neurons can fire around 500-800 APs per second.

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7
Q

Action potentials: All-or-None Principle:

A

All-or-None Principle:

Once an Action Potential (AP) is triggered, it travels along the axon without changes in strength.
Similar to a bullet leaving a gun.
The strength of the AP does not change based on the intensity of the stimulus.
Intense stimuli are represented by a higher rate of firing, not a stronger AP.
Think of it like a few or several bullets firing, not larger or smaller bullets, or faster or slower bullets.

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8
Q

Action Potentials (AP):Level of skin stimulation:

A

Action Potentials (AP):

Level of skin stimulation:
Mild stimulation (A)
Medium stimulation (B)
Strong stimulation (C)
The size of the AP does not change.
However, the number of APs does, depending on the strength of the stimulus.
More APs fire in response to stronger stimulation, but the individual APs remain the same size.

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9
Q

Neurons and Information Representation:

A

Neurons have a baseline level of activation, known as spontaneous activity.
Stimuli can either increase or decrease this baseline activity.
Neurons convey different information through multiple pathways.
Despite sending a single unvarying signal (Action Potential), they affect other neurons in diverse ways.
This leads to the question: How do neurons influence one another?

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10
Q

Neural Transmission:

A

Neurons do not physically touch each other; they have small gaps known as synapses.
Communication between neurons occurs through the transmission of chemical messengers (neurotransmitters) from the pre-synaptic neuron (PreSN) to the post-synaptic neuron (PSN).
At the synapse, the communication switches from electrical to chemical transmission.

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11
Q

Neurotransmission Process:

A

Neurotransmitters are released by synaptic vesicles in the Pre-SN.
They are received by receptor sites on the PSN.
Each receptor site only binds to specific types of neurotransmitters, similar to locks and keys.
Consequently, there are several classes of neurotransmitters, each with different functions.

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12
Q

Excitatory Effects of Neurotransmitters:

A

Excitatory neurotransmitters result in the depolarization of the post-synaptic neuron (PSN), making it more likely to fire an action potential (AP).
When enough excitation occurs, often from multiple pre-synaptic neurons, the threshold for firing an AP is reached.
The function of a neurotransmitter depends on its type, the location of its action, and other factors.
For example, glutamate is associated with learning, while dopamine plays a role in addiction and reward processing.

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13
Q

Psychopharmacological Drugs and Neurotransmitters:

A

Many psychopharmacological drugs work by altering neurotransmitter (NT) function.
Examples include Selective Serotonin Reuptake Inhibitors (SSRIs) in Major Depressive Disorder (MDD).
Dopamine antagonists are used in the treatment of psychosis.
Most illegal drugs have addictive potential due to their effects on NT systems, such as methamphetamine and cocaine, which are dopamine (DA) agonists.

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14
Q

Post-Synaptic Neuron (PSN) Function:

A

The PSN either fires or doesn’t fire based on the combined excitatory and inhibitory effects of all pre-synaptic neurons.
A complex network of neurons allows for information processing and flexibility of action.
This enables the brain to respond selectively rather than passively reacting to every stimulus, such as someone asking for your name.

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15
Q

Sensory Coding - Specificity Coding Limitations:

A

Specificity coding, where unique neurons represent each sensory detail, has limitations.
It would require an enormous number of neurons to represent everything we perceive, which is impractical.
For example, representing every variation of an apple (varieties, colors, shapes, sizes, half-eaten, etc.) would be infeasible.
Neurons constantly die, which would result in a random loss of perception and memory.
Therefore, it’s unlikely to be the primary way information is represented in the brain.

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16
Q

Population Coding:

A

Each object is represented by the firing of all neurons in a network.
Robust to the loss of individual neurons because the pattern of activation remains the same.
Can represent many different aspects of an object, such as different orientations, colors, and shapes of an apple, etc.

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17
Q

Limitations of Population Coding:

A

It may require a substantial number of neurons and complex neural networks.
Understanding how the brain precisely decodes and interprets population-coded information is challenging.
The neural circuits involved in population coding are not fully understood, and the mechanism is still an active area of research.

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18
Q

Population Coding: Limitations

A

Expensive
* Wiring cost
* Energy utilization
* Cumbersome (prone to errors)
* Memory (confusing phone numbers)

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19
Q

Sparse Coding:

A

In sparse coding, an object is represented by the pattern of firing of a subset of neurons, while others remain silent.
This coding method is used to represent information in various sensory systems, including visual, auditory, and olfactory.
For example, it can be applied to represent the pitch of a sound, where specific neurons fire to represent particular pitch values while others stay quiet.

20
Q

Types of Coding in the Brain:

A

All three types of coding (specificity coding, population coding, and sparse coding) are used in the brain.
Population coding and sparse coding are commonly employed in processes such as perception, reasoning, and memory. These coding methods enable the brain to efficiently represent and process information in different contexts.

21
Q

Levels of Analysis for Cognitive Functions:

A

Crash Course on Neurons: Understanding the basics of how individual neurons function.
Levels of Analysis: Examining cognitive functions from various perspectives.
Neuronal Representation: Investigating how neurons or sets of neurons represent information at the micro level.
Localized Representation: Studying how specific brain regions represent information at a localized, regional level.
Distributed Representation: Exploring how multiple brain regions work together to represent information at a broader scale.
Neural Networks: Understanding how large networks of interconnected brain regions collectively represent and process information.

22
Q

Localized Representation:

A

Localized representation involves the concept of localization of function, where specific functions are served by particular areas of the brain.
For example, there is a distinct brain area known as the fusiform area responsible for processing faces.
Broca’s area (Brodmann Area 44) is another localized brain region involved in language production. It was famously identified through the case of Patient Tan, who could only utter the word “tan,” as documented by Paul Broca in 1861.

23
Q
  • What is the deficit in Broca’s
    aphasia?
A
  • Slow, labored, ungrammatical
    speech due to damage
    (stroke/injury) in Broca’s area
  • But able to convey some content
24
Q

What is the deficit in Wernicke’s
aphasia?

A

The deficit in Wernicke’s aphasia is characterized by fluent and grammatically correct speech, but it is often incoherent. Individuals with Wernicke’s aphasia have difficulty understanding other people’s speech, matching words with their meanings, and using the rules of grammar. In essence, while Broca’s patients struggle to use grammar, Wernicke’s patients have difficulty conveying meaningful and coherent language.

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Further evidence for localization of function
Damage to the occipital lobe can lead to cortical blindness, affecting vision. The auditory cortex is responsible for processing auditory information and hearing. The primary somatosensory cortex is crucial for the perception of touch, pressure, and pain. The frontal lobes play a role in higher cognitive functions, such as thinking and problem-solving. Prosopagnosia, the inability to recognize faces, is linked to damage in specific areas like the fusiform face area. Modern imaging techniques, such as fMRI and PET scans, provide additional support for the localization of various brain functions, helping researchers map specific cognitive processes to distinct brain regions.
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Functional Magnetic Resonance Imaging (fMRI) (Q)
Blood contains hemoglobin (which contains iron) * Hemoglobin carries Oxygen to the cells * Neural activity in the brain is associated with increased flow of oxygenated blood to that brain region * Hemoglobin in de-oxygenated blood responds more strongly to magnetic fields than oxygenated blood * This blood oxygenation level dependent (BOLD) signal difference can be identified by powerful magnets placed around the head
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Functional Magnetic Resonance Imaging (fMRI) (Q) works
* This information can be converted into maps of activity by computers * Red/yellow—greater activation * Activation in regions (voxels), not individual neurons * 2-3mm cubes * fMRI allows us to see live activity in the brain when the person is * Doing something (thinking, problem solving, remembering, talking, etc.)-- task-related fMRI * Or resting—resting state fMRI
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Localized Representation: Evidence for Localization
Fusiform Face Area: Activated in fMRI when individuals view pictures of faces.
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Localized Representation: Evidence for Localization
Parahippocampal Place Area: Becomes active when viewing spatial layouts, such as indoor and outdoor scenes.
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levels of analysis for cognitive functions
Neuronal Representation: Focuses on how individual neurons or sets of neurons represent information. Localized Representation: Examines how specific brain regions represent information. Distributed Representation: Explores how multiple brain regions work together to represent information. Neural Networks: Investigates how large networks of interconnected brain regions collectively represent and process information.
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Distributed Representation:
Historical localization studies were primarily based on localized injuries, often due to accidents like penetrating bullet wounds. An illustrative case is Phineas Gage (1848), who experienced significant personality changes after a frontal lobe injury. He went from being social, friendly, and respectful to exhibiting disinhibited behavior, swearing, and a lack of planning or respect for others. The famous saying about Gage is, "Gage was no longer Gage." Advanced imaging techniques, such as fMRI, support localization but also reveal that brain regions are not entirely modular; they often work in distributed networks for various functions.
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Distributed Representation:
The brain relies on multiple regions to process complex information, illustrating the concept of distributed representation. For example, when you see a picture, various brain regions work together: Facial recognition helps you identify who is in the picture. Memory recall allows you to remember where you've seen these images before. Language processing helps you understand any accompanying text, like "They are walking in the snow." These functions involve the coordination of multiple brain regions to process and make sense of the information.
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Distributed Representation: Evidence
Evidence for distributed representation can be seen when looking at a face or an image, as it involves various brain regions identifying different aspects: The presence of a face activates the Fusiform Face Area (FFA). Emotions (happy, sad, angry) are processed by the amygdala. Intent or focus (where they are looking) engages the temporal lobe. Perceptions of cuteness involve the prefrontal cortex (PFC). Memory recall may be linked to previous experiences like reading Calvin and Hobbes and enjoying it. Imagining facial expressions or considering factors like feeling cold also contribute to the distributed representation of facial information.
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Distributed Representation: Evidence
Most cognitive constructs, like memory, are complex and multifaceted. Memory can be categorized into episodic (personal events) and semantic (general knowledge) components. Within memory, various types include visual, auditory, and olfactory memories. Additionally, emotions often have an influential role in memories. This complexity of memory demonstrates that it involves the collaboration of several brain regions working together to form a distributed representation.
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Distributed Representation: Evidence
Language processing in the brain involves multiple regions, including Broca's area, Wernicke's area, and the connection between the two (arcuate fasciculus), as well as various other brain regions. Conduction aphasia is a condition where individuals have difficulty linking speech comprehension and production, despite both of these functions being intact. This condition is characterized by an inability to repeat sentences or answer questions coherently. The presence of conduction aphasia suggests that language processing involves a distributed network of brain regions that collaborate in the complex task of understanding and producing speech.
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levels of analysis for cognitive functions
Neuronal Representation: Examines how individual neurons or sets of neurons represent information. Localized Representation: Focuses on how specific brain regions represent information. Distributed Representation: Explores how multiple brain regions collaborate to represent information. Neural Networks: Investigates how very large networks of interconnected brain regions collectively represent and process information. Default Mode Network: An essential network in the brain that is active when the mind is at rest and not focused on the outside world, playing a role in self-referential thinking, introspection, and mental time travel.
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Neural Networks
Neural networks are governed by four key principles: Structural Connectivity (Structural MRI): This refers to the "roads" or pathways in the brain. Some are like highways, conveying a lot of information, while others are like smaller roads. Functional Connectivity (fMRI): This concept is akin to the traffic on different brain "roads." Highways tend to be busier than small roads, reflecting the flow of information. Example: Default Mode Network (DMN): Just as in a city, some roads always have some level of traffic, representing continuous neural activity. Dynamics of Cognition: Similar to traffic patterns changing at different times or days of the week, cognition and brain activity can also vary under different conditions and demands.
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Neural Networks: Structural Connectivity
Structural connectivity refers to the complex structural pathways or networks that form the brain's information highway. It can be thought of as the roadmap or wiring diagram of the brain, illustrating how different regions of the brain are connected to each other. In some representations, colors like red may indicate left-right connections, blue may represent top-bottom connections, and green may signify anterior-posterior connections, providing insight into the brain's intricate wiring and connectivity.
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Diffusion Tensor MRI (dMRI):
dMRI is based on the principle of Brownian motion, which describes how particles, like a drop of ink in water, diffuse randomly. This diffusion behavior is mathematically described by an equation first proposed by Einstein. In the brain, water molecules also exhibit diffusion, which is somewhat even in regions without interference (isotropy), such as in the cerebrospinal fluid (CSF). However, in the presence of obstacles like axons, water molecules tend to spread more easily in the direction of the axon than in other directions, creating anisotropy. This property is critical for understanding the structural connectivity of the brain, as it can reveal the orientation of axonal pathways.
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Diffusion Tensor MRI (dMRI)
In MRI, the anisotropy of water diffusion in the brain can be mapped by observing the properties of hydrogen protons, ultimately creating a map of the brain's structural connectivity, particularly in white matter regions. MRI generates images of brain structures by examining how the brain responds to magnetic fields. The term "connectome" refers to the comprehensive map of connections between all neurons in the brain, providing valuable insights into the brain's intricate wiring and functional networks.
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Neural Networks: Functional Connectivity
Functional connectivity is the concept of how structural brain networks create functional pathways that serve various cognitive functions. It focuses on the extent to which neural activity in two brain regions is correlated. If the activity in two regions is correlated, they are considered functionally connected. Functional connectivity can manifest as an increase, decrease, or even an anti-correlation (inversely related) of neural activity between regions, which plays a crucial role in cognitive functions, much like traffic patterns in a city like Calgary.
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Neural Networks
Two brain areas may be functionally connected when: Both are structurally connected, indicating that there is a physical pathway for information to pass from the first region to the second. For example, the primary and secondary visual areas are structurally connected. Both regions are receiving inputs from another area, even if they are not directly structurally connected. For instance, the Default Mode Network involves regions that are functionally connected because they share input from a common source, despite not having a direct structural connection
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Neural Networks: Default Mode Network (DMN)
The Default Mode Network (DMN) is a network of brain regions that become active when a person is not engaged in a specific task or focused on external stimuli. It can be likened to the Trans-Canada highway for brain activity, as it's a prominent neural network involved in introspection, self-referential thinking, and mental time travel. Key regions within the DMN include the medial prefrontal cortex, posterior cingulate cortex, and inferior parietal lobule.
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Neural Networks: Default Mode Network (DMN)
The Default Mode Network (DMN) typically shows default activation when the brain is at rest or when a person is not engaged in a specific task. Activity in the DMN tends to reduce when an individual is actively engaged in a particular task or focused on external stimuli. The DMN is active during mind-wandering, which can occur up to 50% of the time. For instance, it's responsible for those moments when your thoughts drift during boring lectures. Beyond just mind-wandering, the DMN plays a vital role in functions like sleep, memory, and creativity.
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Cognition and Neural Networks
The pattern of neural activity across various networks can change in response to different conditions, much like how traffic patterns in a city's road network vary between working hours and evenings. For example, consider the activation in response to a simple cup of coffee: Visual networks focus on the visual characteristics of the cup. Attentional networks help you pay attention to the cup. Motor networks are responsible for picking up the cup and coordinating the visual-motor actions required. As you drink from the cup, there's an adjustment in strength to account for the changing weight as the cup empties. This illustrates how neural networks adapt to different aspects of cognition and behavior.
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