chapter 24 urinary system Flashcards

1
Q

represent the functional unit of the kidney

A

nephrons

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2
Q

the function of a kidney is to

A

filter the blood and form urine and maintain homeostasis of body fluids”;

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3
Q

blind, cup-shaped end of a renal tubule that completely surrounds the glomerulus

A

Glomerular (Bowman’s) capsule

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4
Q

composed of cuboidal cells with numerous microvilli and mitochondria

A

Proximal tubule

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5
Q

Proximal tubule

functions

A

Functions primarily for selective reabsorption of solutes (especially, nutrients, such as glucose, amino acids, vitamins, etc.)
 Selective reabsorption moves solutes from the filtrate and back into the blood stream

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6
Q

a long, hairpin-shaped loop of the renal tubule

A

Nephron loop (Loop of Henle

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7
Q

Nephron loop (Loop of Henle functions

A

Functions to concentrate extracellular fluid in the medullary tissue

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8
Q

from the proximal tubule

A

Descending limb

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9
Q

leads to distal tubule

A

Ascending limb

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10
Q

cuboidal cells that mostly lack the abundant microvilli

A

Distal tubule

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11
Q

Distal tubule

functions

A

The DCT functions more in tubular secretion than in reabsorption
 Tubular secretion involves the movement of solutes from the bloodstream into the filtrate or forming urine
 Substances that are secreted across the DCT include ions such as K+ and H+, organic dyes, certain antibiotics, etc.

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12
Q

Receive filtrate from nephrons

 Run through the medullary pyramids

A

Collecting ducts

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13
Q

Collecting ducts

functions

A

Collecting ducts function primarily for the selective reabsorption of water from the forming urine; movement of water from the filtrate back into the interstitial fluids results mostly from osmosis
 Permeability of the collecting duct to water molecules is facilitated by the influence of ADH from the posterior pituitary gland
 Collecting tubules converge to form papillary ducts, which deliver urine to minor calyces

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14
Q

small artery that supplies an individual nephron

A

Afferent arteriole

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15
Q

(Glomerular capsule containing a glomerulus)

A

Renal corpuscle

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16
Q

a high-pressure, capillary tuft that is supplied by the afferent arteriole and which occurs within the glomerular capsule; this capillary is specialized for filtering the blood, forming glomerular filtrate, which is then processed by the remainder of the nephron to form urine;

A

Glomerulus

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17
Q

a small blood vessel that drains the glomerulus and supplies the peritubular capillary

A

Efferent arteriole

18
Q

low-pressure capillary specialized for reabsorption of water, nutrients, and other materials and tubular secretion of other materials

A

Peritubular capillary

19
Q

long, straight efferent arterioles, capillaries, and venules of juxtamedullary nephrons which extend into the renal medulla and surround the loop of Henle

A

Vasa recta

20
Q

Flow Chart

A
 Blood in arteriole
 Glomerulus
o 99% of filtrate now enters efferent arteriole, then peritubular capillary bed, then venules
o 1% of the filtrate continues its flow through the nephron
 Glomerular capsule
 Proximal tubule
 Descending limb of nephron loop
 Ascending limb of nephron loop
 Distal tubule
 Collecting duct
 Papillary duct
 Minor calyces
 Major calyces
 Renal pelvis
 Ureter
21
Q

The filtrate:

 Contains all plasma components except

22
Q

Urine formation and adjustment of blood composition involves three major processes:

A

Glomerular filtration
 Tubular reabsorption
 Tubular secretion

23
Q

The glomerulus is more efficient than other capillary beds because:

A

Its filtration membrane is significantly more permeable
 Glomerular blood pressure is higher
 It has a higher net filtration pressure

24
Q

Plasma proteins are not filtered and are used to maintain

A

osmotic pressure of the blood

25
Glomerular Filtration Rate is directly proportional to the Net Filtration Pressure  If the GFR is too high:
Needed substances cannot be reabsorbed quickly enough and are lost in the urine
26
Glomerular Filtration Rate is directly proportional to the Net Filtration Pressure If the GFR is too low
Everything is reabsorbed, including wastes that are normally disposed of
27
Three mechanisms control the GFR
``` Renal autoregulation (intrinsic system)  Neural controls  Hormonal mechanism (the renin-angiotensin system) ```
28
Autoregulation entails two types of control | responds to changes in pressure in the renal blood vessels
Myogenic mechanism
29
Autoregulation entails two types of control | senses changes in NaCl concentration
Tubuloglomerular feedback
30
Hormonal: Renin-Angiotensin Mechanism: |  Is triggered when specific cells in the kidney release
renin
31
Renin acts on angiotensinogen to release
angiotensin I
32
Angiotensin I is converted to
angiotensin II
33
Angiotensin II:  Causes mean arterial pressure to ?  Stimulates the adrenal cortex to release?  As a result, both systemic and glomerular hydrostatic pressure?
rise aldosterone rise
34
Neural control:  When the sympathetic nervous system is at rest:  Renal blood vessels are ?  Autoregulation mechanisms
maximally dilated | prevail
35
neural control Under stress:  Norepinephrine is released by the ?  Epinephrine is released by the ? Afferent arterioles constrict and filtration is inhibited  The sympathetic nervous system also stimulates the ?
sympathetic nervous system adrenal medulla renin-angiotensin mechanism
36
A process where most tubule contents are returned to the blood
Step 2 of Urine Formation: Tubular Reabsorption
37
Step 2 of Urine Formation: Tubular Reabsorption All organic nutrients are ? Water and ion reabsorption is?  Reabsorption may be an active (requiring ATP) or passive process
reabsorbed | hormonally controlled
38
Loop of Henle reabsorbs
H2O in the descending limb |  Several types of solutes in the ascending limb
39
During glomerular filtration, is the main force pushing water and solutes out of the blood and across the filtration membrane.
glomerular hydrostatic pressure (the glomerular blood pressure)
40
GHP = glomerular hydrostatic pressure | GHP is opposed by 2 forces that drive fluids back into capillaries:
1. Colloid osmotic pressure of glomerular blood (GCOP)  Colloid osmotic pressure = Pressure created by large nondiffusible molecules 2. Capsular hydrostatic pressure (CHP) exerted by fluids in the capsule