Chapter 26: Drugs Affecting Blood Pressure

Question 1

Classification of Catopril

Answer 1

Angiotension-Converting Enzyme Inhibitors

Question 2

Angiotension Converting Enzyme Inhibitor

Answer 2

Catopril

Question 3

Indications of Catopril

Answer 3

HTN, CHF, diabetic neuropathy, left ventricular dysfunction

Question 4

Medication used for HTN, CHF, diabetic neuropathy, left ventricular dysfunction

Answer 4

Catopril

Question 5

MOA of Catopril

Answer 5

Inhibits the ACE needed to change angiotensin I to angiotensin II

Question 6

active form of angiotensin

Answer 6

angiotensin II

Question 7

Works by inhibiting the conversion of angiotensin I to angiotensin II

Answer 7

Catopril

Question 8

Adverse effects include persistent nonproductive cough, angioedema, rash, hypotension, neutropenia, dyspnea

Answer 8

Catopril

Question 9

Catopril’s adverse effects

Answer 9

persistent nonproductive cough, angioedema, rash, hypotension, neutropenia, dyspnea

Question 10

Contraindications of Catopril

Answer 10

Hypersensitivity & 2nd/3rd trimester of pregnancy

Question 11

Vasodilation can cause:

Answer 11

decrease in BP

Question 12

Which drug should be administered 1 hour before meals?

Answer 12

Catopril

Question 13

Catopril’s absorption is decreased with:

Answer 13

food

Question 14

When taking Catopril, the blood tests should test for:

Answer 14

hyperkalemia, hyponatremia, neutropenia, proteinuria in urine

Question 15

hyperkalemia, hyponatremia, neutropenia, proteinuria in urine should be monitored for patients taking this drug:

Answer 15

Catopril

Question 16

Mechanism results in a decrease in peripheral arterial resistance and sodium/water retention

Answer 16

Catopril

Question 17

Angiotensin II Receptor Blocker:

Answer 17

Losartan

Question 18

Indications include HTN, diabetic neuropathy, left ventricular dysfunction

Answer 18

Losartan

Question 19

Losartan is used in patients with:

Answer 19

HTN, diabetic neuropathy, left ventricular dysfunction

Question 20

Alpha 2 agonist drug

Answer 20

Clonidine

Question 21

secondary anti-hypertensive medication administered PO, IV or transdermal

Answer 21

Clonidine

Question 22

Secondary anti-hypertensive medication that does not affect kidney blood flow or GFR

Answer 22

Clonidine

Question 23

Clonidine patch should be changed every ___ days

Answer 23

7

Question 24

Drug that selectively blocks the binding of angiotensin II to the angiotensin I receptors in tissues

Answer 24

Losartan

Question 25

Losartan MOA

Answer 25

selectively blocks the binding of angiotensin II to the angiotensin I receptors in tissues

Question 26

Adverse Effects of Losartan

Answer 26

Hypotension, diarrhea, asthenia, dizziness, fatigue

Question 27

Adverse effects include Hypotension, diarrhea, asthenia, dizziness, fatigue

Answer 27

Losartan

Question 28

Only contraindication is hypersensitivity

Answer 28

Losartan

Question 29

Losartan's contraindications

Answer 29

hypersensitivity

Question 30

Interacts with lithium, flucanazole, indomethacin, rifampin and grapefruit juice

Answer 30

Losartan

Question 31

Losartan interacts with:

Answer 31

lithium, flucanazole, indomethacin, rifampin and grapefruit juice

Question 32

Grapefruit juice ____ metabolism of Losartan

Answer 32

decreases

Question 33

Levels that should be monitored during taking Losartan

Answer 33

creatinine, BUN, hemoglobin, hematocrit

Question 34

Creatinine, BUN, hemoglobin & hematocrit levels should be monitored in patients taking:

Answer 34

Losartan

Question 35

Classification of Eplerenone

Answer 35

Selective aldosterone blocker

Question 36

Selective aldosterone blocker:

Answer 36

Eplerenone

Question 37

Indication for Eplerenone

Answer 37

HTN

Question 38

MOA of Eplerenone

Answer 38

binds selectively to the mineralocorticoid receptors, blocking aldosterone from binding

Question 39

Works by binding selectively to the mineralocorticoid receptors, blocking aldosterone from binding to receptors

Answer 39

Eplerenone

Question 40

Adverse Effects include hyperkalemia, diarrhea, albuminuria, gynecomastia, abnormal vaginal bleeding, and hypercholesterolemia

Answer 40

Eplerenone

Question 41

Adverse effects of Eplerenone

Answer 41

hyperkalemia, diarrhea, albuminuria, gynecomastia, abnormal vaginal bleeding, and hypercholesterolemia

Question 42

Normal range of potassium

Answer 42

3.5-5 mEg/L

Question 43

Contraindications of Eplerenone

Answer 43

Potassium over 5.5 mEg/L, creatinine > 2 mg/dL

Question 44

salt substitutes are ___ based

Answer 44

potassium

Question 45

statins may cause:

Answer 45

severe leg aching pains