chapter 27: lower respiratory stuff Flashcards

(103 cards)

1
Q

Acute bronchitis

A

usually from viruses, but also irritants and asthma
-3 week cough
-NO fluid build up in lungs from consolidation
-may have fever, hoarseness, aches, dyspnea, pain
-gol of treatment is to relieve symptoms and prevent pneumonia

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2
Q

Perussis

A

Super contgious infection caused by Bordetella pertussis which attaches to and damages cilia
-TDAP vaccine is super important

“Whooping cough” –> might not be present in teens and adults –> happens more at night

contagious from onset to 3rd week or 5 days aft antibiotics

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3
Q

Pertussis phases

A

1) 1-2 weeks URT infection and nonproductive cough

2) weeks 2-10 paroxysyms of coughs

3) 2-3 weeks = weakness and less severe cough

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4
Q

Treatment do’s and dont’s for pertussis

A

-diagnose with cultures and PCR
-treat with macrolide or trimethoprim/sulfamethoxazole
-give antibiotics to ppl who were exposed too

-no cough suppressants or antihistamines
-no corticosteroids or bronchodilators

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5
Q

Pneumonia
-what?
why?
entryways

A

acute infection of lung parenchyma
-typically happens when immune defenses are compromised or overwhelmed –> chronic diseases make it worse

Pathogens enter lungs in 3 ways:
1. aspiration of normal flora from nasopharynx or oropharynx
2. inhalation of microbes in air (mycplasma pneumoniae)
3. hematogenous spread from other infection (streptococcus aureas from endocarditis)

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6
Q

Community acquired pneumonia (CAP)

A

Not from hospital (no hospitalization within 14 days)
Use CURB-65 to decide wheteher to treat in hospital

Confusion
U: BUN>20
Respiratory rate >30
Blood pressure <90/60
65 or older

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7
Q

Hospital acquired pneumonia (HAP)

A

-nonintubated patient –> 48+ hrs after admission
-ventilator associated pneumonia (VAP) –> 48+ hrs after intubation

Empiric antibiotics to treat

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8
Q

Viral and bacterial pneumonia

A

Viral
-most common
-mild to life threatening

Bacterial
-often hospitalized

Mycoplasma pneumonia has traits of viral and bacterial –> “atypical”

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9
Q

Aspiration Pneumonia

A

-stuff from moth or stomach enters lungs
-LOC, NG tubes, and swallowing issues
-usually more than one bacteria involved –> need antibiotics for G- and MRSA
-if acidic stuff from stomach causes issues –> “chem/noninfectious” –> no antibiotics

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10
Q

Necrotizing Pneumonia

A

-rare complication of lung infection turning tissue into thick liquid
-absesses and cavitization are possible
-resp failure and airway bleeding
-don’t really know reasons for it
-Staphylococcus, Klebisella, and Streptococcus involved
-long term antibiotics and possibly surgery

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11
Q

Opportunistic pneumonia

A

in immunocompromised patients
-protein malnourishment, HIV, radiation/chemo, long term corticosteroids

PJP pneumonia = fungal - slow, subtle onset
-tachycardia, fever, tachypnea, dyspnea, nonproductive cough, hypoxemia
-spreads to other organs (liver, bone marrow, lymph nodes, spleen, thyroid)
-doesn’t respond to antifungals–> use bactrim or sptra

CMV (herpes) can cause pneumonia

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12
Q

Pathophysiology for pneumonia

A

inflammation, neutrophils, edema, fluid leaks, hypoxemia

Atelectasis (nothing in alveoli) causes shortness of breath

Consolidation (fluid in alveoli) impairs gas exchange –> with treatment/time, macrophages get rid of this stuff

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13
Q

Manifestations of pneumonia

A

cough, fever, chills, dyspnea, tachypnea, and pleuritic chest pain
-cough may or may not be productive with any color of sputum

Old ppl might just be confused and have hypothermia rather than fever

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14
Q

Chest sounds of pneumonia

A

-course or fine crackles

If consolidation:
-bronchial breath sounds
-egophony
-increased fremitus

If pleural effusion
-dullness to percussion

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15
Q

Complications of pneumonia

A

MDR pathogens
atelectasis
pleurisy (inflammation of plaura)
pleural effusion
Bacteremia (bacterial blood infection)
pneumothorax (air in pleura makes lungs collapse)
acute respiratory failure
sepsis/septic shock

RARE:
-lung abscess (S. aureas and G-)
-emphysema (need antibiotics and drainage)

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16
Q

Diagnostic studies for pneumonia

A

history, phys exam and xray are enough to get started
-thoracentesis or bronchoscopy can get fluid for testing if patient isn’t responding to treatments
-ABGs and WBC assessment
-sputum sample to treat specific bacteria

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17
Q

Treatment of pneumonia

A

-antibiotics (should help in 48-72 hrs if uncomplicated)
-follow up xray in 6-8 weeks
-O2, analgesics, antipyretics as needed
-activity if tolerable

***usually not much you can do for viral pneumonia - resolves on its own in 3-4 days –> antiviral stuff can help if pneumonia from influenza or herpes

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18
Q

drug therapy for pneumonia

A

-empiric antibiotics including stuff to fight MDR pathogens and G- and G+
-switch to oral meds ASAP
-Get ppl out of hospital ASAP
-patient should be afebrile for 48-72 hrs before stopping treatment

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19
Q

Nutrition therapy for pneumonia

A

HYDRATION!!!!!!! –> thins and loosens secretions

Small, frequent meals to get enough cals for heightened metabolism –> eating can be hard bc shortness or breath

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20
Q

positions that prevent aspiration

A

upright and side-lying

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21
Q

ways to prevent pneumonia post op

A

-early mobilization
-incentive spirometer
-oral hygiene 2x a day with chlorhexidine swabs

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22
Q

Tuberculosis

A

infection caused by mycobacterium tuberculosis
-usually affects lungs, but can affect any organ
-kills poor people and HIV

Resistance is a huge problem –> MDR-TB (first line drugs) and XDR-TB (all the rest, including fluoroquinolones)

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23
Q

Mycobacterium tuberculosis facts
-contagion

A

-G+, aerobic, acid fast bacillus
-tiny droplets airborne (not super contagious though)
-humans are only reservoirs
-once in bronchioles/alveoli, Ghon lesion/focus forms (calcified TB source) to kill it (usually successful)

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24
Q

Classification of TB

A

Primary = initial immune response fails and disease progresses (“active”) w/in 2 yrs of infection

Reactivation = happens more than 2 yrs later

Latent = what it sounds like –> can be activated with immunosuppression, diabetes, bad nutrition, pregnancy, stress, aging, disease

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25
How long after infection do symptoms show up? cough progression early symptoms late symptoms?
2-3 weeks (except when it is acute) starts dry then becomes productive fatigue, malaise, weight loss, fever, chest pain dyspnea and hemoptysis *sometimes night sweats
26
TB presentation in old or HIV ppl
HIV: less likely to have signs of infection -symptoms sometimes wrongly attributed to PJP old ppl -sometimes only display change in mental status
27
Miliary TB
widespread dissemination of the mycobacterium -causes swelling of lymph, liver, spleen -from primary or LTBI TB
28
Pleural TB
-extrapulmonary -from primary or LTBI -chest pain, fever, cough, PLEURAL EFFUSION -emphysema not as common -diagnosed with biopsy and AFB cultures
29
Potts syndrome
TB in spine
30
TB skin test
-use purified protein derivative (PPD) for M tuberculosis -check 2-3 days later for induration (no redness) -5 mm = positive -2 step testing w/ Mantoux TST for baseline
31
Interferon-y release assays
-blood tests that detect INF-y release fom T cells -only require one visit and are more accurate -can't differentiate bt LTBI and active
32
How accurate are chest xrays for TB diagnosing? What about bacteriologic studies?
-chest xrays aren't great -gold standard! --> 3 specimen 8-24 hrs apart --> can take a long time though
33
How long are TB ppl contagious?
-if sputum smear is positive, they're contagious for first 2 weeks after starting treatment
34
Drug therapy for TB
Initial and continuation phase Initial: -4 drug regimen for 8 weeks -isoniazid, rifampin, pyrazinamide, ethambutol Continuation: -2 drugs for 18 weeks -isoniazid and rifampin CAUTION: ALC AND ISONIAZID DON'T MIX -nonviral hepatitis is a possible side effect
35
Drug treatment for MDR and XDR TB
-guided by sensitivity testing MDR -usually 5 drugs for 6 months -then 4 drugs for 18-24 months Sirturo and Deltyba treat MDR and XDR
36
Directly observed therapy (DOT)
-Watch them take the meds -Nonadherance is big issue with spread of MDR-TB -can use combo pills to make it easier for ppl
37
Latent TB drug treatment
-usually only need 1 drug (typically isoniazid for 9 months) -6 month regimen is less effective, but better for adherence -ppl w/ HIV or fiberobtic chest lesions need full 9 months -3 month of isoniazid AND rifapentine if no MDR -4 month rifampin if resistant to isoniazid
38
Bacille Calmette-Guerin (BCG) vaccine
-live attenuated strain of Mycobacterium bovis Not used so much in U.S. -no help with pulmonary TB -interferes with TB skin test -no effect on IGRA though
39
Who do you report positive TB tests to?
public health authorities
40
3 things to do if someone comes into ER with suspected TB
1. airborne precautions (fitted HEPA masks) 2. chest xray, sputum smear, culture 3. drug therapy
41
Ambulatory care
-its ok to go home if fam is already exposed -sputum for AFB every month until 2 in a row are neg -reduce exposing others --> spend time outside -stick to drug regimen -teach how to recognize relapses -STOP SMOKING
42
Atypical Mycobacteria
-acid fast mycobacteria that cause pulmonary disease -not airborne or droplet -cough, SOB, weight loss, blood-tinged sputum -can't differentiate bt this and TB w/o culture
43
Pulmonary Fungal Infections
-E.g. fungal pneumonia caused by endemic fungi (e.g. Coccidioides) -Opportunistic fungal infections Inhalation of spores --> not contagious similar to pneumonia antifungals given -Amphotericin B IV for serious systemic infection
44
Lung abscess
necrosis of lung tissue -usually from aspirated bacteria, but also from IVs, cancer, pulmonary emboli, TB, parasites, and fungi usually more than one anaerobic microbe in back part of upper lobe of lung foul smelling sputum "necrotizing pneumonia"
45
manifestations and lung sounds of lung abscess
Stand out symptoms: -purulent sputum that smells and tastes gross -hemoptysis when abscesses pop Others: -fever, chills, preostration, night sweats, pleuritic pain, dyspnea, weight loss Lung sounds: -less lung sounds -bronchial sounds might move peripherally -crackles in later stages
46
spreading of lung abscess
-goes through blood -bronchopulmonary fistula, bronchiectasis, and empyema from popping of abscess into pleural cavity
47
Diagnostic study of lung abscess
- chest xray -CT scan helps too -sputum isn't great bc it'll have oral flora if coughed up -Bronchoscopy can help get sample and look for cancer -pleural fluid and blood can help identify the microbe
48
Nursing care for lung abscess Doctor care
-monitor vitals and look for hypoxemia -give O2 and antibiotics -food, rest, water -DONT do chest PT or postural drainage -percutaneous drainage or surgery if unresponsive to drugs
49
Lung Tumors (not cancer)
Hamartomas = slow, benign tumor made of fiber, fat, and blood vessels Mucous gland adenoma = benign tumor made of columbar cystic spaces in bronchi Mesotheliomas = may or may not be benign --> visceral pleura --> melignant ones assoc w/ asbestos
50
Fractured ribs
-most common injury from blunt trauma -ribs 5-9 -pain, shallow breaths, possibly atelectasis and pneumonia Don't strap chest --> limits ability to expand Use pain meds, deep breathing, spirometer
51
Flail chest
-happens when 3+ ribs in 2+ places are fractured, forming unstable segment -that part moves opposite of normal chest -tachycardia, shallow breaths -treat like any rib fracture
52
Pneumothorax
air enters pleural cavity ruining the neg pressure -causes lung collapse open = entering through chest wall closed = no external wound tachycardia, dyspnea, air hunger, low O2, no breath sounds
53
Spontaneous pneumothorax
rupture of blebs on lung surface -blebs are there more in smokers -tall, thin males get it more
54
Iatrogenic pneumothorax
puncture during med procedures -barotrauma from excessive ventilation
55
Tension pneumothorax
air can't escape from pleural space and pressure keeps rising -crushes lung on affected side and pushes mediastinum to other side where it crushes other lung --> also heart is being crushed can happen with chest tubes that're clamped MED EMERGENCy!!! --> Needle decompression and chest tube insertion
56
Hemothorax
blood accumulation in pleural space --> needs to be drained --> blood may be reusable
57
Chylothorax
lymph fluid in pleural space -usually happens bc trauma or cancer fucks with thoracic duct -need meds and/or surgery
58
Treatment of pneumothorax
-cover wound secured on 3 sides -if impaled, don't remove object -chest tube connected to water-seal drainage -maybe surgery
59
Chest tube dimensions
20" long 36-40F for draining blood 24-36F for draining fluid 12-24F for draining air 10-14F = pigtail (also for air)
60
inserting chest tube
patient is upright (30-60*) with arms above head -incision over a rib and tube goes over rib -sutures it in place -sealed with airtight petroleum gauze
61
Flutter or Heimlich valve
device used to remove air from pleural space -can walk around with it --> bag under clothes
62
Pleural Drainage systems 3 compartments
1. collection chamber 2. water seal chamber which acts as a one way valve 3. suction control chamber: wet or dry -wet suction determined by water level -dry suction uses restriction device or regulator
63
should we be clamping chest tubes during transport?
nah bro -way riskier bc of tension pneumonia -just reestablish water seal ASAP
64
When can you clamp chest tubes
just temporarily when changing the drainage apparatus or checking for air leaks
65
risks of quickly removing 1-1.5 L through chest tube
-reexpansion pulmonary edema -severe hypotension
66
what happens when air leaks into tissue around chest tube?
subcutaneous emphysema --> can lead to swelling of head and neck --> obstruction
67
how much is too much drainage from chest tube?
over 200 ml Call HCP!
68
thoracotomy
surgical incision to get to heart, lungs, esophagus, throacic aorta, or anterior spine 1. sternotomy for heart 2. posterolateral for lung 3. anterolateral for trauma victims
69
What to check before thoracotomy
-cardiopulmonary status -chest xray ECG ABG CBC PT/INR aPTT
70
After a thoractotomy
PAIN MANAGEMENT --> MOST PAINFUL INCISION -assess breathing, sputum, vitals, wound
71
Thoracentesis
aspiration of intrapleural fluid for diagnostic purposes -usually no more than 1000 to 1200
72
Restrictive respiratory disorders -side note: whats a hallmark of obstructive disorders?
extrapulmonary intrapulmonary = lungs or pleura Decreased total lung capacity (stops expansion) Obstructive: if obstructive, decreased forced expiratory volume
73
Atelectasis
collapsed, airless alveoli -often bc airways blocked by secretions -post op patients
74
Pleurisy
inflammation of pleura -abrupt, sharp pain on inhalation -shallow rapid breathing usually a side effect, not a primary condition
75
Pleural effusion types ***usually bc of malignancy
transudate = pale yellow fluid w/o cells or protein --> usually HF or low albumin exudate = inflammatory rxn causes increased capillary permeability empyema = purulent fluid in pleura due to pneumonia, TB, lung abscesses, and infected wounds
76
Pleural effusion manifestation
pain that doesn't radiate less movement on one side
77
Interstitial lung disease
tissue bt air sacs of lungs is inflammed or scarred -200 dif disorders
78
Idiopathic pulmonary fibrosis
SMOKING CAUSES IT WEIGHT LOSS AND FATIGUE AND CLUBBING DO A CHEST XRAY AND VATS O2 therapy and pulmonary rehab no real cure --> ppl die --> 30-50% 5 yr survival STEROIDS
79
Sarcoidosis
granulomatis disease --> unknown cause -can affect a bunch of dif organs -follow up with pulmonary function, xray, and CT **ppl usually die with it, not of it **black men get this STEROIDS
80
pulmonary edema
usually bc of HF -fluid in alveoli and interstitial spaces
81
Pulmonary embolism ***cancer is #1 cause bc of extra cells
-blocking of pulmonary arteries with thrombus, fat, or air -DVT/VTE -sometimes upper extremety DVT from catheters/arterial lines
82
manifestations of pulmonary emboli
dyspnea and mild hypoxemia if it gets real bad there's change in mental status, hypotension, acidosis, and feeling of impending doom
83
pulmonary embolism complication
Pulmonary infarction (death of lung tissue) --> usually accompanied by pleural effusion Pulmonary hypertesion --> can lead to hypertrophy of right ventricle
84
diagnostic study for pulmonary embolism
D-dimer --> not sensitive or specific helical CT scan!!!!!!!!!!!!!! V/Q scan = IV radioisotope and Radioactive gas (perfusion and ventilation)
85
Important tests for pulmonary embolism that aren't diagnostic
ABG chest xray ECG troponin B-type natriuretic peptide
86
Treatment for PE: supporting cardiopulmonary status
O2 = intubation/ mechanical ventilation pulmonary hygiene = prevent atelectasis shock = fluids and vasopressors HF = diuretics Pain = opioids
87
drug therapy for PE
ANTICOAGULANTS + blood thiiners (heparin and warfarin) Fibrinolytic agents to dissolve clot (tPA and activase)
88
surgical therapy for PE
If big: pulmonary embolectomy -good if hemodynamically unstable and thrombolytic therapy is contraindicted Percutaneous catheter embolectomy or endovascular ultrasound delivered thrombolysis Inferior vena cava filter for high risk ppl who can't take anticoagulants --> stops migration of clots into pulmonary system
89
Nursing management of PE
Prevention -compression devices -early ambulation -anticoagulants Immediate treatment -bed rest in semi fowlers -check cardiopulmonary status -give O2, IV fluids, meds -Monitor: coagulation and complications
90
Pulmonary hypertension
high pulmonary artery pressure due to high resistance MAP -Normal = 12-16 -HTN = over 25 at rest; over 30 exercising can be main or secondary disease (r sided hf)
91
5 classess of pulmonary hypertension
1) a/w meds, disease, genetics, idiopathic 2) left sided HF 3) lungs and hypoxemia 4) CV system and thromboembolic occlusion 5) multifactorial (hematologic or metabolic involvement)
92
Idiopathic pulmonary arterial hypertension (IPAH)
Results in right HF and death if untreated Possible causes -CT disease, cirrhosis, HIV Results in -vascular scarring, endothelial dysfunction, smooth muscle proliferation affects females more
93
Manifestations of IPAH
dyspnea and fatigue -chest pain, dizziness, syncope Eventually dyspnea at rest and right ventricle hypertrophy
94
Diagnostic studies for IPAH
RIGHT SIDED HEART CATHETERIZATION -ECG, chest xray, PFTs, echo, CT
95
Early recognition and drug therapy for IPAH
Note unexplained SOB, syncope, chest pain, and edema Drugs -pulmonary vasodilation -manage edema -prevent thrombi -prevent hypoxia
96
surgical interventions for IPAH
Pulmonary thromboendarterectomy (PTE) -Atrial septostomy (AS) = palliative -lung transplant
97
Secondary pulmnoary arterial hypertension (SPAH)
Chronic increase in pulmonary artery pressure from other disease -parenchymal lung disease -LV dysfunction -intracardiac shunts -chronic PE -CT disease
98
Symptoms, diagnosis and treatment of SPAH
dyspnea, fatigue, chest pain, right hypertrophy and HF Diagnosis = same as IPAH Treatment: underyig cause --> if irreversible, IPAH therapies
99
Cor Pulmonale
Enlarged right ventricle secondary to disorder of respiratory system; COPD -usually already has pulmonary hypertension --> maybe HF too Manifests: same as IPAH --> sometimes polycythemia -if HF: water retension and big liver
100
Lung transplant is for what?
ESLD -COPD, pulmonary fibrosis, cystic fibrosis, IPAH, alpha antitrypsin deficiency
101
Preop for lung transplant
evaluateion ensure no contraindictions (cancer, HIV, Hep B/C, psych issues, smoker, poor nutrition) -need to adhere w/ post op regimen UNOS gives LAS score to determine who gets lungs
102
surgery types for lug transplant
single lung bilateral lungs heart-lungs lobes from living related donors
103
lung transplant rejection
Acute: 5-10 days -fever, fatigue, dry cough, O2 desaturation Chronic: Bronghiolitis obliterans -progressive airflow obstruction unresponsive to bronchodilators and corticosteroids