Chapter 3 Flashcards
Wrote a book on “uroscopy”
5th century BCE
Instruction in urine examination as part of their training
Middle ages
Development of 20 different color charts
1140 CE
He discovered albuminuria by
boiling of urine
Frederick Dekkers
There is a progress from “ant
testing” and ”taste testing” for glucose
1694
passing of the first medical licensure law in England
1627
Examined and quantified urinary sediment
Thomas Addis
The invention of microscope led to the examination and
quantitation of urinary sediment by Thomas Addis
17th century
introduced the concept of urinalysis as
part of routine patient examination
Richard Bright
Richard Bright introduced the concept of urinalysis as
part of routine patient examination
1827
the number and complexity of the tests performed in a
urinalysis had reached a point of impracticality, and
urinalysis began to disappear from routine examinations.
1930s
kidneys continuously form this as an
ultrafiltrate of plasma
Urine
Reabsorption of water and filtered substances
essential to body function converts into how much volume of filtered plasma?
Approximately 170,000 mL
Average daily urine output
1200 mL
Composition of urine
95% water
5% solutes
Factors affecting urine composition
dietary intake
physical activity
body
metabolism
endocrine functions
Organic substances in urine
Urea
Creatinine
Uric acid
Inorganic substances in urine
Chloride
Sodium
Potassium
Other substances found in urine
Hormones
Vitamins
Medications
Other substances found in urine
Hormones
Vitamins
Medications
Urine may also contain:
Cells
Casts
Crystals
Mucus
Bacteria
Primary organic component in normal urine
Urea
Product of metabolism of creatine by muscles
Creatinine
Product of breakdown of nucleic acid in food and cells
Uric acid