Chapter 3 Flashcards
(47 cards)
Two concepts that under lie the cognitive approach
- Information processing depends on internal representations.
- These mental representations undergo internal transformations.
Transcranial magnetic stimulation (TMS)
Provides focal stimulation of brain noninvasively; directly stimulates neurons
- produced at either high (excitatory) or low (inhibitory) frequencies
What do CAT, MRI, and DTI all do?
Give information on structure of the brain
MRI
Maps brain areas in detail using magnetic properties of atoms that make up organic tissue
CAT
Inject dye into blood and pass x-rays through the head; allows 3D reconstruction
DTI
Neuroimaging that uses an MRI to image all white matter pathways (Myelination)
What do EEG, ECoG, Single-cell recording, and MEG have in common?
They all measure neural activity
Single-cell recording
Used to monitor the activity of individual neurons; measures change in membrane potential
-invasive technique using electrodes
MultiUnit recording
An array of electrodes is inserted into the brain to help understand the activity of many cells
ECoG
A grid of strip electrodes is inserted in the brain to help understand the activity of many cells
-invasive
Are single cell recordings, ECoG, and multiunit recordings invasive or noninvasive?
invasive
EEG
Surface recording made from electrodes placed on scalp; good for temporal resolution
MEG
Measures magnetic signals generated by the brain
- magnetic detectors are placed on the scalp that measure the electrical activity of neurons
- noninvasive
What is hemodynamic response?
Detect change in blood flow
PET
Measure metabolic activity or blood flow changes in the brain by monitoring the distribution of a radioactive tracker
fMRI
Utilizes an MRI to track blood flow changes in the brain that may be correlated with local neural changes
Event-related potentials-
A change in electrical activity that is time-locked to specific events such as the presentation of a stimulus or
onset of a response
- measured by EEG
What two imaging techniques exemplify hemodynamic response?
PET and fMRI
Block design
Experimental design that consist of blocks of multiple trials of the same type
DBS (deep brain stimulation)
Surgical implants of a microelectrode
directly in the brain.
- used for depression, OCD, other life altering disorders
- last resort
optogenetics
A technique (viral transduction) that allows researchers to turn on activity in targeted neurons by a device that shines a light within the brain by using a specially manipulated virus to insert light-sensitive proteins into
the membrane of a given type of neuron.
knockout procedure
Scientists manipulate a specific gene (or set of genes) such that it
does not express itself, and then study the knockout strains to explore the consequences of this change.
agonist
drug that binds to the receptor, producing a similar response to the intended chemical and receptor
antagonist
drug that binds to the receptor either on the primary site, or on another site, which all together stops the receptor from producing a response.