Chapter 34 Flashcards

(73 cards)

1
Q

diagnostic evaluation of breast disorders

A
  • U/S exam can differentiate fluid filled cysts from solid tissue (more likely to be malignant)
  • fine needle aspiration (FNA): can be done to remove fluid or small tissue fragments for analysis of cells
  • core biopsy: uses a larger needle to obtain a cylinder of tissue from an area of questionable breast tissue
  • open/surgical biopsy: performed to remove all/part of the lump if other conditions exist like bloody fluid aspirated, recurrence of cyst after 1 or 2 aspirations, solid dominant mass, serous/serosanguineous nipple discharge, signs suspicious of inflammatory breast cancer, suspicious mammography
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fibrocystic Breast Changes

A
  • benign breast disorder
  • common changes that occur during the reproductive years before menopause
  • fibrosis (thickening) of breast tissue occurs in early stages
    • cysts form later
  • not cancerous, but if involved in terminal breast ducts may inc risk of cancer
  • common symptoms: pain and tenderness
    • pain is bilateral and most noticeable during PMS
    • pain likely due to imbalance of estrogen to progesterone ratio
  • to help manage: wear supportive bra, avoid caffeine and stimulants, oral contraceptives
    • can use some pharmacological methods like Danazol to suppress estrogen production but this can only be ued for 4-6 mos
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fibroadenoma

A
  • benign breast tumor
  • most common during teens-20s
  • firm, freely mobile nodules that may or may not be tender
  • do not change during mentrual cycle
  • usualy located in upper, outer quadrant
  • tx: careful observation to ensure that it is stable
    • may excise the mass if changes in size
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

ductal ectasia

A
  • benign
  • occurs as a woman approaches menopause
  • characterized by dilation of collecting ducts, which become distended and filled with cellular debris
    • this initiates an inflammatory response which results in a mass near the areola that feels firm/irregular, enlarged axillary nodes, nipple retraction and discharge
  • must have a biopsy b/c S/S are similar to breast cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

intraductal papilloma

A
  • benign
  • often develops just before or during menopause
  • occurs when papillomas (small elevations) develop in the epithelium of the ducts under the areola
    • as it grows, it causes trauma and erosion w/in the ducts that leads to serous/bloody discharge from the nipple
  • U/S and mammography aid in dx
  • tx: excision of mass plus analysis of nipple discharge
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

nursing considerations for benign disorders of breast tissue

A
  • acknowledge anxiety
    • they may find it helpful to learn that most breast disorders are benign
  • explain diagnostic procedures
    • teach about what the procedure entails and how long the woman will have to wait for results
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

carcinoma in situ

A
  • malignant neoplasm in surface tissue
  • lumpectomy is usually performed
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

incidence of malignant tumors of the breast

A
  • white women after age 35 have a higher incidence than African American women
    • but African American women have a higher incidence until the age of 35
  • African American women have a higher risk of dying from breast cancer
    • b/c of faster growing tumors and diagnosed more often at a more advanced stage
  • Asian American, Hispanic, and Native Indian have a lower risk of developing cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

risk factors for malignant turmors of the breast

A
  • mutations in BRCA1/2 are thorught to be responsible for most cases of familial breast and ovarian cancer
  • mutation of CHEK-2 has higher risk of development of breast cancer in men and women
  • mutation of p53 tumor suppressor gene has been assoc with breast cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

inflammatory breast cancer

A
  • has cutaneous findings w/ invasive involvement in the dermis
  • rare but more likely to occur in younger or African American women
  • aggressive and may manifest as a pink or red skin rash
  • tenderness, itching, or breast edema may be present
    • often seems like an infection, so prescribed abx, so if the rash doesn’t go away, contact HCP
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

staging of breast cancer

A
  • based on TNM: tumor, node, metastasis
  • Stage 1: small tumor w/o lymphatic involvement in the local area or metastases
  • Stage 4: indicates spread to LNs and metastases to distant organs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

lumpectomy

A
  • involves wide local excision of the tumor to microscopically clean margins for tumors that are small relative to the breast size
  • AKA breast conservation tx
  • can be performed w/o deformity
  • some axillary LNs are removed to identify stage of breast cancer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

mastectomy

A
  • simple mastectomy: removal of the entire breast
    • axillary dissection is omitted, but some LNs may be removed
    • can also be used prophylactically, but if no cancer present, does not eradicate risk for later breast cancer
    • do not take BP on affected side
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

radiation therapy

A
  • a type of adjuvant therapy
  • known to improve chance of long term survival
  • uses high energy rays to destroy cancer cells that remain in the breast, chest wall, and underarm area after surgery
    • also irradiate LNs above clavicle and the internal mammary LNs
  • skin over affected area may have rxn similar to sunbrun
  • lymphedema is more likely to occur if axillary LNs are treated
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

chemotherapy

A
  • designed to kill the proliferating cancer cells
  • combo of drugs and # of tx varies for each woman
  • may both precede and follow tumor removal
  • often kill normal cells (esp those rapidly dividing like in mucosa, blood cells, and platelets)
    • often leads to sore, bleeding gums; susceptibility to infection; loss of head/body hair; menstrual irregularities; anemia (and fatigue)
  • antiemetics are often used for woman on chemo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

hormone therapy

A
  • reduce production of estrogen b/c many tumors are estrogen/progesterone receptor positive
  • tamoxifen: estrogen blocking drug
    • some tumors become resistant and the drug may actually stimulate their growth
    • may elevate calcium, cholesterol, and triglycerides
  • anastrzole, exemestane, and letrozole: aromatase inhibitors which hinder production of estrogen
  • raloxifene: estrogen modifier which reduces osteoporosis by blocking estrogen receptors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

immunotherapy

A
  • trastuzumab (herceptin) is a biologically based therapy that targets cell pathways that promote cancer growth
    • some tumore produce excessive amounts of the HER-2 protein which promotes cell growth, but this drug blocks this protein to inhibit growth of cancer cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

nursing considerations of breast cancer

A
  • emotional support and accurate info need to be provided to the woman
    • woman needs time to express her feelings
    • nurse should be empathetic
  • provide a clear understanding of procedures and care to help reduce anxiety
  • lymphedema: caused by blockage drainage of lymphatic system in the arm on the side of the mastectomy
    • compression arm sleeves help control lymphedema
  • discharge teaching: self care and need for continued care/tx
    • teach how to reduce risk of infection, how to care for arm on affected side, S/Es post op and from meds,
    • teach how to empty drains
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

amenorrhea

A
  • absence of menses
  • normal: before menarche, during pregnancy, during puerperium and lactation, and after menopause
  • abnormal: at other times
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

when should mentrual periods begin?

A
  • mentrual periods should begin w/in 2 yrs of breast development
    • b/w the ages of 9-15 yo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

primary amenorrhea

A
  • considered if onset of menstrual periods has not occurred by 16.5 yo, particularly if associated sexual changes have not taken place
    • may be suspected if the girl is more than 1 yr older than the ages at which her mother/sisters had menarche
  • causes:
    • genetic: ovarian failure
      • may occur in girl w/ Turner’s Syndrome (X); hormonal imbalances; cancer
    • systemic
      • low body weight for height (athletes, eating disorders), chronic stress, hypothyroidism, CNS dz, drug use
  • mgmt: depends on cause
    • counseling
    • hormone therapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

secondary amenorrhea

A
  • cessation of menstruation for 6 mos or more in a woman who had established a pattern of menstruation, or absence for duration of 3 normal cycles
  • causes:
    • pregnancy
    • systemic dz: DM, TB, hypothyroidism, CNS lesions, hormonal imbalance, poor nutrition, hormonal contraceptives
    • stressors
  • tx: tx the cause
    • pregnancy test
    • hormone level testing
    • tx of anovulation
    • ID of other abnormalities
      • PCOS: characterized by acne, excess weight, body hair
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

nursing considerations w/ amenorrhea

A
  • emotional support
  • teaching about adequate nutrition and exercise as well as discouraging rigourous dieting
  • weight control may reduce factors related to PCOS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

abnormal uterine bleeding

A
  • menorrhagia: prolonged or heavy bleeding
  • metrorrhagia: bleeding that is irregular and occurs b/w periods
  • menometrorrhagia: combo of the previous 2
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
etiology of abnormal uterine bleeding
* pregnancy complications (ie spontaneous abortion) * anatomic lesions, either benign or malignant, of vagina, cervix, or uterus * drug induced bleeding, such as breakthrough bleeding that may occur in woman taking hormonal contraceptives * systemic disorders, such as DM, uterine myomas (fibroids), and hypothyroidism * failure to ovulate
26
abnormal uterine bleeding: mgmt
* evaluation may include pregnant test, coagulation studies, and test to determine if ovulation is occurring * hormone and liver function tests as well as tests to determine anemia are done * U/S may be used to look for polyps * hormone tx: progestin-estrogen combo oral contraceptives that suppress ovulation and allow a stable endometrial lining to form * surgical therapy: D&C to remove polyps or to diagnose endometrial hyperplasia * may use laser ablation to remove the endometrial lining w/o hysterectomy
27
abnormal uterine bleeding: nursing considerations
* encourage women to seek medical attn promptly when irregular or prolonged bleeding occurs * help woman keep record of bleeding episodes and amount of blood lost * noting vaginal bleeding and pads/tampons saturated each day * encourage importance of adequate nutrition and discourages rigorous dieting * provide support for women who fear that irregular bleeding indicates a serious dz * but do not offer false reassurance
28
menopause
* the end of mentruation * climacteric: the entire process of menopause including endocrine, somatic, and psychic changes that occur at the end of the reproductive period * premenopause: early part of climacteric * before menstruation but after the woman experiences some of the climacteric S/S like irregular menses * perimenopause: include premenopause, menopause, and at least 1 yr after menopause * postmenopause: phase after menopause when menstrual periods have ceased * unexpected bleeding during this period should be investigated ASAP b/c may indicate endometrial cancer
29
age of menopause
* avg age is 51.5 yrs * natural climacteric takes place over 3-5 yrs * menopause can be induced or created artificially at any age * surgical removal of ovaries or destruction of the ovaries by radiation/chemo causes abrupt cessation of ovarian function * most common reason for these procedures is tx of cancer or endometriosis
30
physical changes of menopause: ovulation, estrogen, hot flashes
* ovulation is sporadic and mentrual periods are irregular during premenopause * eventually ovulation, menstruation, and secretion of ovarian hormones cease * estrogen declines and organs of reproduction regress * labia: thin and pale * vaginal mucosa: atrophies * vaginal tissue loses lubrication and dyspareunia is common * frequent vaginal infections--\>atrophic vaginitis * LDL increases and HDL decreases * hot flashes: result of vasomotor instability * cause is associated with inc secretion of gonadotropins * more frequent at night and fatigue often results
31
physical changes of menopause: testosterone, osteoporosis, heart dz
* decreased testosterone levels: * changes in libido * mood changes * sleep changes b/c of dec tryptophan (serotonin precursor) * osteoporosis risk inc * heart dz risk inc
32
physical effects on the woman's body from menopause
* remains orgasmic * pendulous breasts * atrophy of ovaries, vagina, and fallopian tubes * thinning of pubic hair * labial regression * vaginal dryness * smooth, thin mucosa w/ decreased ruggae and elasticity * vaginal pH inc
33
psychological aspects of menopause
* influenced by: * the woman's expectations * accurate knowledge * general physical well-being * family view * marital stability * socio-cultural expectations * greater stability = easier transition * often times menopause brings about coming to terms with aging: no longer can have a child, becoming grandparents * S/S: mood swings, depression, irritability, agitation, insomina, fatigue
34
recommendations during menopause
* consult HCP about botanical preparations * maintain/establish adequate nutrition * use water soluble lubricants * regular exercise * kegel exercises * modest caffeine and alcohol * drink 8 glasses of H2O
35
therapy for menopause
* hormone replacement therapy (HRT): combination of estrogen and progesterone replacement therapy * ACOG stopped recommending it in 2002 * WHI: * inc risk of breast cancer and heart dz w/ combo of estrogen and progesterone replacement therapy * inc risk of strokes w/ estrogen replacement therapy * contraindications: unexplained uterine bleeding, endometrial cancer * also smoking, HTN, diabetes, CV dz, renal/liver dz, seizures, migraines, gallbladder/pancreatic dz
36
nursing considerations during menopause
* help women understand the changes that may occur * edu about risks and benefits of HRT if prescribed * teach them about the recommendations for uring water soluble lubricants to relieve vaginal dryness and dyspareunia * do Kegel exercises to counteract genital atrophy * drink at least 8 glasses of water/day to dec conc of urine, flushes urine from bladder, and reduces bacterial growth * wipe front to back to prevent cystitis
37
osteoporosis
* characterized by dec bone density which leaves the bones porous, fragile, and susceptible to fracture * fractures most common in vertebrae, wrists, and hips (but also in forearms, feet, toes) * assoc with lower estrogen and androgen levels
38
risk factors of osteoporosis
* combination of peak bone density and rate of bone loss influences severity of osteoporosis * small boned, fair skinned white women of northern European descent and Asian women are at greatest risk for osteoporosis * family hx of dz * late menarche * early menopause * sedentary lifestyle * smoking, drinking alcohol, consumption of excessive caffeine * drug intake of cortiocosteroids, some anticonvulsants, or aromatase inhibitors for rbeast cancer may reduce bone density * inadequate intake of vit D and calcium
39
S/S of osteoporosis
* first noticeable sign is loss of height and back pain that occurs when vertebrae collapse * later signs include dowager's hump (when vertebrae can no longer support the upper body in an upright position), waist disappears, abdomen protrudes as rib cage moves closer to the pelvis * dx requires a hx, exam, and bone mineral analysis
40
DXA bone density scan
* may be recommended if: * over 50 and have a broken bone * you are a woman over 65 or a man over 70 * yo are in menopause or past menopause and have risk factors * you are a man age 50-69 w/ risk factors * uses low dose x-rays to measure bone density in the hip and spine * can confirm osteoporosis and detect low density before a frx and predict a frx * repeated scans determine rate of bone loss and monitor tx effectiveness
41
prevention of osteoporosis
* dec alcohol, caffeine, smoking * Fosamax (alendronate) or Bisphosphonate to slow bone thinning and improve thickness * Evista (raloxifene): prevents/txs and decreases cholesterol * calcium: 1200-1500 mg/day * vitamin D: 400-800 units/day * regular weight bearing/resistance exercise * diet high in vitamins E, D, and B complex * protein: 80 grams/day
42
Bisphosphonates
* class of drugs that slows bone thinning and improves thickness * used to prevent and tx postmenopausal osteoporosis * may be contraindicated if a woman has an ulcer or dysphagia or esophagitis * ie Alendronate, Ibandronate, Risedronate, Zoledronic acid * may inc risk of venous thromboembolism and death from stroke
43
nursing considerations for osteoporosis
* counsel women about lifestyle factors that can cause bone loss: smoking, alcohol, caffeine * counsel adolescents and young women about factors to promote ideal peak bone density * prevention of falls * make environment safe: ample lighting, no loose electrical cords, nonskid backing on rugs, grab bars , handrails
44
S/S of ovarian cancer
* bloating * pelvic or abdominal pain * trouble eating or feeling full quickly * feeling the need to urinate urgently or often * fatigue * upset stomach or heartburn * back pain * dyspareunia * constipaion or menstrual changes * persistent vaginal itching * blood in stool
45
risk factors for ovarian cancer
* menses started at \<12 yo * no child or first child after 30 yo * late menopause (\>55 yo) * infertility * family hx of ovarian, breast, or colorectal cancer * personal hx of breast cancer
46
prevention of ovarian cancer
* oral contraception * breast feeding and pregnancy * tubal ligation * hysterectomy * prophylactic oophorectomy
47
ovarian cancer: diagnosis
* pelvic exams * transvaginal sonography * CA-125 tests * BRCA test
48
ovarian cancer treatment
* earliest stage: total abdominal hysterectomy, bilateral salpingo--oophorectomy, removal of ovarian tissue * surgery followed by chemo * but sometimes do chemo to reduce tumor's size, then a hysterectomy or a salpino-oophorectomy
49
Pelvic Inflammatory Dz
* infection of the upper genital tract * can lead to ectopic pregnancy or infertility * more likely to develop if under 25 b/c cervix is not mature which inc the susceptibility to infectious organisms * also inc risk of infection if multiple sex partners * douching inc risk for PID b/c canges natural vaginal flora
50
etiology of PID
* most from C. trachomatis and N. gonorrhoeae * some also caused by E. coli, streptococcus, group B strep. CMV * organism invades endocervical canal where they cause cervicitis * the organisms ascend and infect the endometrium, fallopian tubes, and pelvic cavity * chronic inflammatory response results in tubal scarring and peritubal adhesions which interfere with conception or w/ transport of fertilized ovum thru the obstructed falloppian tubes to the uterus
51
S/S of PID:
* pelvic pain * fever * purulent vaginal discharge * anorexia * irregular bleeding * physical exam: abdominal or adnexal (accessory organ) tenderness and tenderness of the uterus/cervix during bimanual exam * labs: * leukocytosis: inc WBC * inc sedimentation rate * positive cultures
52
mgmt of PID
* IV abx--broad spectrum * cefoxitan * cefotetan * clindimycin + gentomycin * usually changed to PO after 48 hrs and total duration of abx is usually 14 days * laparoscopy can rule out surgical emergencies like appendicitis or ectopic pregnancy and to obtain cultures
53
nursing considerations for PID
* prevent STDs to prevent PID: teach about this and how to prevent * primary prevention: avoiding exposure to dz or preventing acquisition during exposure * limiting # of sexual partners, avoid intervourse w/ those who had multiple partners, avoiding high risk behaviors like injectable drugs, condoms * secondary prevention: keeping a lower genital tract infection from ascending to the upper genital tract * seek medical attn promptly, periodic medical assessment, taking meds as prescribed
54
toxic shock syndrome (TSS)
* caused by a strain of S. aureus * rare, potentially fatal * toxin alters capillary permeability which allows intravascular fluid to leak from the blood vessels, leading to hypovolemia, hypoTN, and shock * toxin also causes tissue damage and defects in coagulation * assoc with high absorbency tampons, cervical caps, diaphragm
55
danger signs of TSS
* suddenly spinking a fever (102 F, 38.9 C) * siarrhea * vomiting * muscle aches, sore throat * sunburn like rash * hypoTN
56
nursing considerations for TSS
* tx includes fluid replacement, vasopressor drugs, antimicrobial therapy * instruct women to: * tampon use: * wash hands before insertion * change tampons q4 hrs to prevent excessive bacterial growth * do not use superabsorbent tampons * use pads during hours of sleep * diaphragm/cervical cap: * wash hands * do not use during menstrual period * remove w/in time recommended
57
cystocele
* occurs when weakened anterior wall of the vagina can no longer support the weight of urine in the bladder, so the bladder protrudes downward into vagina * results in incomplete emptying of bladder * cystitis likely to occur * stress urinary incontinence may occur due to the urethral displacement when the urethra bulges into the anterior vaginal wall
58
enterocele
* prolapse of upper posterior vaginal wall b/w the vagina and rectum * most assoc with herniation of pouch of Douglas (fold of peritoneum dips down b/w rectum and uterus) * often accompanies uterine prolapse
59
rectocele
* occurs when posterior vagina becomes weak and thin * each time woman strains at defecation, feves are pushed against the thin wall and cause further stretching until the rectum protrudes into vagina * if large, may have problems emptying rectum * some women facilitate bowel elimination by applying pressure along the posterior vaginal wall to keep rectocele from protruding during bowel movement
60
uterine prolapse
* occurs when cardinal ligaments are unduly stretching during pregnant and do not return to normal * allows the uterus to sag backward and downward into vagina * common if woman has had many vaginal deliveries or when infants are large * significance: when uterus is displaced, it impinges on other structures in lower abdomen * bladder, rectum, and small intestine can protrude thru vaginal wall
61
symptoms of uterine prolapse
* most obvious during menopausal period * b/c estrogen diminishes leading to atrophy of the supporting structures * most common: * feelings of pelvic fullness * dragging sensation * pelvic pressure * fatigue * low backache * sexual problems related to arousal, orgasm, and painful vaginal intervourse
62
mgmt of uterine prolapse
* tx depends on woman's age, physical condition, sexual activity, and degree of prolapse * surgery may be needed * pessary: device to support pelvic structures that is inserted into the vagina * must be inspected and changed frequently
63
nursing considerations for uterine prolapse
* PFMT (kegel exercises): isometric, contract and relax slowly 8-12 times for 6-8 sec each and do 3 sets * should not tighten muscles of abdomen, thighs, and buttocks * exhale and keep mouth open and avoid bearing down * continue for rest of life * evaluate urinary incontinence: can be stress or urge * overactive bladder may also occur and is accompanied by sensations of urgency and nocturia * may need bladder training * do not restrict fluid * weight mgmt * limit caffeine and alcohol * skin care * social isolation
64
4 types of hysterectomies
* partial hysterectomy: only uterus removed * total hysterectomy: both uterus and cervix are removed * total hysterectomy w/ bilateral salpino-oophorectomy: both ovaries, fallopian tubes, uterus, and cervix are removed * radical hysterectomy: both ovaries, fallopian tubes, uterus, cervix, and LNs are removed
65
STIs
* can have an STI and not know it * can know about an STI and not be honest * genital skin/genital skin contact, oral/genital skin contact, oral/anal contact, blood, sexual fluids can spread an STI * latex condoms are very effective * abstinence and mutual monogamy w/ an uninfected partner is ideal
66
Trichomoniasis
* protozoan * thrives in an alkaline environment * S/S: purulent vaginal discharge that is thin or frothy, malodorous, and yellow-green or brownish gray * pH of discharge is usually greater than 4.5 * vulvar itching, edema, and redness may occur * tx: metronidazole * 2 g in a single oral dose * avoid alcohol while on medication and for 24 hours after last dose * sexaul partners should refrain from intercourse until cure is established
67
Bacterial Vaginosis
* normal flora replaced * tissue trauma and vaginal intercourse may be contributing factors * as well as multiple partners, douching, and lack of vaginal lactobacilli * S/S: thin, grayish white vaginal discharge w/ a fishy odor * tx: based on re-establishing normal flora * metronidazole: can relieve symptoms and improve vaginal flora * clindamycin: alternative * refrain from sexual intercourse until cured and use a condom
68
chlamydia trachomatis
* most common STD * most common in sexually active teens and young adults * often asymptomatic in young women * should be suspected if male partner is treated for nongonococcal urethritis and when culture for gonorrhea is negative, but woman has symptoms similar to gonorrhea * if untreated, can ascend and scar fallopian tubes--\>PID, infertility, ectopic pregnancy * tx: eradicate both chlamydia and gonorrhea * azithromycin, doxycycline, ofloxacin, levofloxacin, erythromycin * treat al sexual partners * must use condom until cured
69
Gonorrhea
* caused by neisseria gonorrhea * often asymptomatic in women * S/S: purulent discharge, dysuria, dyspareunia * assoc with PID (inc risk of infertility and ectopic pregnancy) * tx: can use the same drugs as chlamydia tx as well as ceficine, ceftriaxone, and ciprofloxacin * tx all sexual partners and avoid intercourse and wear condom until cure established
70
syphilis
* caused by Treponema pallidum * Primary: painless chancre usually on genitals or lips * highly contagious * Secondary: occurs 2 mos after initial infection * enlargement of spleen and liver, skin rash, HA, anorexia, skin rash, skin eruptions on vulva * Latent: for several years * Tertiary: follows latent phase and may involve the heart, blood vessels, and CNS * general psychosis and paralysis may result * lab tests: Venereal dz Research Lab (VDRL) serum test to check for antibodies; rapid plasma reagin (RPR) and fluorescent treponemal antibody absorption (FTA-ABS) confirm a positive VDRL * penicillin G is most effective
71
herpes genitalis
* caused by HSV: type 1 and 2 * type 1: oropharyngeal infection * type 2: genital lesions * transmission thru direct contact w/ infected person * w/in 2-12 days after primary infection, vesicles (blisters) cluster on genitals * may cause severe pain, tenderness, dyspareunia, and flulike symptoms * when symptoms abate, virum remains dormant in nerve ganglia and reactivates in times of stress, fever, and menses * no cure exists by antivirals help reduce/suppress symptoms, shedding, and reoccurrence (acyclovir) * abstain from sex during times of active lesions * C/S if blister present
72
human papilloma virus (HPV)
* genital warts * dry, wart like growths may be small and discrete, or they may cluster and resemble cauliflower * most commonly on vulva, vagina, cervix, or anus * assoc with cervical cancer, so need frequent pap smears * tx: goal is to remove warts to prevent transmission * topical tx: podophyllin, TCA, and BCA * cryotherapy (extreme cold) * laser vaporization * all sexual partners must be treated and sexual contact should be avoided if lesions are present * use a condom to reduce transmission
73
candidiasis
* moniliasis and yeast infections are the most common forms * cause is related to a change in vaginal pH that allows accelerated growth of Candida albicans * change in pH likely with pregnancy, DM, OC use, abx, spermicide * more common in sexually active women although not a STD * male partners may experience erythema and itching of the glans penis * S/S: vaginal and perineal itching, vulvar and vaginal tissue are inflamed and cause burning on urination, white "cottage cheese" discharge * tx: butoconazole, miconazole, clotrimacole, terconazole, tioconazole * most nonprescription meds are used for 3-7 days * oral fluconazole can be used w/ prescription * if severe, then may need another dose in 4 days * recurrent yeast infections that resist tx are assoc with DM and HIV infection