Chapter 37 Neuraminidase Inhibitors Flashcards Preview

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Flashcards in Chapter 37 Neuraminidase Inhibitors Deck (3)
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1
Q

MOA neuraminidase inhibitors

A

neuraminidase cleaves sialic acid from membrane glycoproteins and permits release of the virus; so w/o it the virus can’t spread to other cells and is tethered to the cell surface

2
Q

how is zanamavir administered

A

inhaler b/c it has poor oral bioavailability

3
Q

what is oseltamavir used for prophylactically

A

H5N1 avian influenza “bird flu”