Chapter 4 Flashcards
(7 cards)
1
Q
What is a homeobox?
A
A homeobox is a highly conserved region consisting of
180 nucleotides that is found in many morphogenetically
active genes. Homeobox gene products act as transcription
factors.
2
Q
Which of the following is a transcription factor? A. FGF B. Pax C. TGF D. Notch E. Wnt
A
B. Pax
3
Q
Where in the cell is the retinoic acid receptor located?
A
In contrast to many receptors, the receptors for retinoic
acid (α, β, and γ) are located in the nucleus.
4
Q
A mutation of what receptor is the basis for basal carcinomas of the skin? A. Patched B. Retinoic acid C. Notch D. FGF receptor E. None of the above
A
A. Patched
5
Q
Zn finger or helix-loop-helix arrangements are characteristic of members of what class of molecules? A. Proto-oncogenes B. Signaling molecules C. Receptors D, Transcription factors E. None of the above
A
D. Transcription factors
6
Q
Based on your knowledge of paralogous groups, which gene would be expressed most anteriorly in the embryo? A. Hoxa-13 B. Hoxc-9 C. Hoxd-13 D. Hoxb-1 E. Hoxb-6
A
D. Hoxb-1
7
Q
Sonic hedgehog is produced in which signaling center?
A. Notochord
B. Intestinal portals
C. Floor plate of neural tube
D. Zone of polarizing activity in the limb bud
E. All of the above
A
E. All of the above
