Chapter 5 Flashcards
(29 cards)
genetic linkage
genes that travel together more often than not
recombination
the separation of genes on the same chromosome
syntenic
genes located on the same chromosome
gametes that carry the allele combination seen in the original female or male of the P generation
parental types
recombinant types
gametes that have allele combinations produced by reshuffling; not seen in the parental generation
parental classes
the combinations originally present in the P generation
recombination classes
combinations resulting from cross-overs
linked genes
when the number of F2 progeny with parental genotypes exceeds the number of F2 progeny with recombinant genotypes
physical markers
allowed the researcher to understand and see the process of recombination through experimental evidence
genetic markers
alleles of genes that could serve as points of reference in determining whether particularly progeny were the result of recombination
How does recombination contribute to genetic diversity?
Reshuffling the alleles of genes between homologous chromosomes.
Crossing-over also plays an even more critical role to ensure that chromosomes segregate properly when they are transmitted between parents and their progeny
Cohesin
molecular complexes that involve the physical linkage between homologous chromosomes
interference
ensures that each chromosome pair undergoes at least one crossovers, thus preventing nondisjunction of any chromosome except when rare mistakes occur
recombination frequency reflects the distance between two genes
the closer two genes are on a chromosomes, the less their chance of being separated by an event that cuts and recombines the line of genes
Alfred H. Sturtevant
Proposed that the percentage of total progeny who were recombinant types (recombination frequency) could be used as a measurement of the physical distance separating any two genes on the same chromosome
Centimorgan
unit of distance between genes
chromosomal interference
the phenomenon of crossovers not occurring independently
coefficient of coincidence
frequency of observed/ frequency expected
Interference
1- coefficient of coincidence
recombination hotspots
small regions of DNA where the frequency of recombination is much higher than average
linkage group
genes chained together by linkage relationships
ascus
sac of four haploid products of each meiosis
tetrad
the assemblage of four ascopores in a single ascus
parental ditype (PD)
four spores in the resulting tetrad that have the parental configuration of alleles