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Dermatology - Chapters > Chapter 5 - Epidermal Growths > Flashcards

Chapter 5 - Epidermal Growths Flashcards

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1
Q

neoplasms of the epidermis are derived from a proliferation of ___ or ____

A

basal cells or keratinocytes

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2
Q

epidermal growths are recognized clinically by a localized thickening of the epidermis that often is accompanied by thickening of the stratum _____, which is called hyperkeratosis or scale

A

corneum

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3
Q

large, indurated, rapidly growing, crusted or ulcerated tumors suggest a ____ process and should undergo a biopsy

A

malignant

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4
Q

benign neoplasms caused by infection of epidermal cells with papillomaviruses

A

wart

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5
Q

thickening of the epidermis with scaling and an upward extension of the _____ containing prominent capillaries give warts their “warty” or verrucous appearance

A

dermal papillae

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6
Q

most common sexually transmitted disease

A

HPV

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7
Q

what type of occupations have a higher incidence of common warts?

A

butchers and meat cutters

EWWW

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8
Q

___ affect sexually active individuals, and their occurrence in children should raise suspicions of sexual abuse

A

Anogential warts (condylomata acuminata)

Call stabler and bension

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9
Q

flesh colored firm papule or nodule that has a corrugated or hyperkeratotic surface, interrupts the normal skin lines and is studded with black puncta, linear fashion from autoinoculation

A

common wart or verrua vulgaris

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10
Q

__ variant of verrucca vulagaris occurs on the head and neck

A

filiform

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11
Q

subtle appearance, flesh colored or reddish brown, slightly raised, flat surfaced 2-5 mm, well marginated papulae

A

flat wart

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12
Q

a single, painful papule on the plantar aspect of the foot, covered by a thick callus

A

plantar wart

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13
Q

__ involves the rectum, perineal region, inguinal folds, external genitalia and occasionally urethra and vagina, soft moist papule and plaque that may be sessile or pedunculated

A

condyloma acuminatum - venereal wart

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14
Q

soaking the genital area for 5 minutes with 3-5% ____ causes warts to turn white

A

acetic acid

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15
Q

Diff Diagnosis of a wart

A 
Callus 
Squamous cell carcinoma
Comedo
lichen planus
corns
Secondary syphilis
Seborrheic keratoses
Bowenoid papulosis
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16
Q

an uncommon disorder characterized by erythematous, sometimes pigmented, papulae occuring in the genital region of sexually active young adults

A

bowenoid papulosis

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17
Q

treatment for warts

A

cryotherapy with liquid nitrogen
electrodesiccation and curettage
surgical excision
laser therapy

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18
Q

most common initial mode of treatment, uses either a cotton tipped stick or a cryospray unit for application of the liquid nitrogen onto the verrua

A

cryotherapy with liquid nitrogen

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19
Q

a potent blistering agent derived from the blister beetle, an alternative office treatment that is applied to common warts and covered with tape

A

Cantharidin

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20
Q

cytotoxic agent that resulted in renal toxicity, polyneuritis, and shock

A

podophyillin

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21
Q

a chemically pure ligand derived from podophyillin is available as topical solution or gel, for patient self treatment of external genital warts

A

Podofilox

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22
Q

t/f warts are contagious

A

True

if they weren’t, sexual partners wouldn’t share them and the book says some guy in the 1800s Jadassohn inoculated normal skin with wart material and warts grew about 2- 3 months after

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23
Q

a localized thickening of epidermis secondary to chronic pressure or friction

A

corn (clavus or heloma)

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24
Q

white gray or yellow brown, well circumscribed, horny papules or nodules

25
diff dx of a corn
plantar wart - if skin lines are present its a corn
26
tx for a corn
paring down with scalpel, mediplast or reduction of trauma (new shoes) or surgery (correction of deformity)
27
a __ will persist unless friction and pressure are relieved.
corn
28
a benign neoplasms of epidermal cells that clinically appears as a scaling, "pasted on" papule or plaque, autosomal dominant inherited trait
seborrheic keratosis
29
vary is size from 2mm to 2cm and slightly to markedly elevated, color ranges from flesh to tan/brown and occasionally black, oval to round, greasy appearing, sharply marginated growths
seborrheic keratosis
30
diff dx of seborrheic keratosis
wart, actinic keratosis, nevus, pigmented basal cell carcinoma, malignant melanoma
31
what type of biopsy confirms the clinical impression of seborrheic keratosis?
excisional or shaved
32
leser-trelat, the rapid increase in size and number of seborrheic keratoses is accompanied by _____
pruritus
33
acrochordon is another name for ___
skin tag
34
a benign fleshy tumor that is frequently acquired in adult life, slightly hyperplastic epithelium covering a dermal connective tissue stalk, pedunculated, flesh colored growth
skin tag
35
soft, tan to flesh colored, 1-10 mm, pedunculated, fleshy papule, has a smooth or folded surface and frequently appears boggy of filiform
skin tag
36
t/f large or necrotic skin tags should be sent to pathology
true! purple box on page 59!
37
caused by a DNA poxvirus that infects epidermal cells, lesions appear smooth, dome-shaped papules that often are umbilicated
molluscum contagiosum
38
papules are 2-5 mm wide, hard, smooth, dome shaped and flesh colored or translucent, central umbilication from which a cheesy core can be expressed, singly or in groups
molluscum contagiosum
39
precancerous neoplasm of the epidermis caused by the UV portion of sunlight
actinic keratosis
40
1-10 mm, reddish, ill-marginated patches and papules that have a rough, yellowish brown, adherent scale
actinic keratosis
41
a malignant neoplasm of keratinocytes, locally invasive and has the potential to metastasize, scaling, indurated plaque or nodule that sometimes bleeds or ulcerates
squamous cell carcinoma
42
second most common skin cancer
squamous cell carcinoma
43
chronic, nonhealing, bleeding growth or ulcer should arouse suspicion of ___
squamous cell carcinoma
44
squamous cell carcinoma in situ of the skin, erythematous, scaling, crusted, well marginated patch
Bowen's disease
45
Squamous cell carcinoma is situ of the glans penis is referred to as ___ , red, velvety, moist patch
erythroplasia of Queyrat
46
rapidly growing neoplasma of the epithelium that is biologically benign but histologically resembles a squamous cell carcinoma, round, flesh colored nodule that characteristically grows rapidly (within 4-6 weeks) and has a central keratin filled crater
Keratoacanthoma
47
Exposure to what carcinogens leads to squamous cell carcinoma?
arsenic and soot, UV, X-irradiation, and viruses
48
a rare genetic disorder, develop hundreds of flat warts caused by HPV and prone to transform into squamous cell carcinoma
epidermodysplasia verruciformis
49
a malignant neoplasm arising from the basal cells of the epidermis, rarely metastasize, types include: nodular, pigmented, superficial and scarring
basal cell carcinoma
50
most common human malignant disease
basal cell carcinoma
51
which TYPE of basal cell carcinoma is most common?
nodular, has a pearly, semitranslucent papule or nodule that often has a central depression or crater, telangiectasia and a rolled waxy border.
52
a shiny, blue-black papule, nodule or plaque, which type of basal cell is this?
pigmented basal cell carcinoma
53
type of basal cell carcinoma that occurs on the thorax, red, slightly scaling, well demarcated, eczematous appearing patch, may become slightly eroded and crusted, subsequently leaving an atrophic, slightly depressed center
superficial basal cell carcinoma
54
atrophic, white, slightly eroded or crusted plaque that often looks like a scar
scarring basal cell carcinoma
55
rare malignant tumor that usually occurs as a solitary nodule on the head and neck of elderly patients
merkel cell carcinoma
56
treatment of ___ includes local excision, sentinel lymph node biopsy and radiotherapy
merkel cell carcinoma
57
hamartoma of the sebaceous glands and other cutaneous structures appears at birth as a thin yellowish plaque with alopecia
nevus sebaceus
58
plaque becomes verrucous and both benign and malignant tumors may develop, excision is recommended, may be associated with neurologic or skeletal abnormalities
nevus sebaceus
59
benign tumor of the hair follicle, solidary or multiple firm, smooth, flesh-colored papules or nodules, inherited as an autosomal dominant condition
trichoepithelioma

Dermatology - Chapters (18 decks)

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