Chapter 7: Hormones of Endocrine System Flashcards
Know class, target and effect of each hormone.
Releasing and inhibiting factors
Peptide
Hypothalamus
TO: anterior pituitary
Effect: modify activity
Growth hormone (GH)
Peptide
Anterior pituitary
Effect: ↑ bone + muscle growth, ↑ cell turnover rate
Prolactin
Peptide
Anterior pituitary
TO: mammary gland
Effect: milk production
Thyroid stimulating hormone (TSH)
Peptide
Anterior pituitary; tropic
TO: thyroid
Effect: ↑ synthesis + release of TH
Adrenocorticotropic hormone (ACTH)
Peptide
Anterior pituitary; tropic
Effect: ↑ growth + secretory activity of adrenal cortex
Luteinizing hormone (LH)
Peptide
Anterior pituitary; gonadotropic
TO: ovary; testes
Effect: ovulation; testosterone synthesis
Follicle stimulating hormone (FSH)
Peptide
Anterior pituitary; gonadotropic
TO: ovary; testes
Effect: follicle development; spermatogenesis
Antidiuretic hormone (ADH, vasopressin)
Peptide
Posterior pituitary
TO: kidney
Effect: water retention
Oxytocin
Peptide
Posterior pituitary
TO: breast; uterus
Effect: milk letdown; contraction
Thyroid hormone (TH, thyroxine)
Modified amino acid
Thyroid
Effect: child: necessary for physical + mental development; adult: ↑ metabolic rate + temperature
Calcitonin
Peptide
Thyroid; thyroid C cells
TO: bone; kidney
Effect: lowers serum [Ca2+]
Parathyroid hormone (PTH)
Peptide
Parathyroids
TO: bone, kidney, small intestine
Effect: raises serum [Ca2+]
Thymosin
Peptide
Thymus - children only
Effect: T-cell development during childhood
Epinephrine
Modified amino acid
Adrenal medulla
Effect: sympathetic stress response (rapid)
Cortisol (“glucocorticoid”)
Steroid
Adrenal cortex
Effect: longer-term stress response; ↑ blood [glucose]; ↑ protein catabolism; ↓ inflammation + immunity; many others
Aldosterone (“mineralocorticoid”)
Steroid
Adrenal cortex
TO: kidney
Effect: ↑ Na+ reabsorption to ↑ BP
Sex steroids
Steroid
Adrenal cortex
Effect: not normally important, but an adrenal tumor can overproduce these, causing masculinization or feminization
Insulin
Peptide
ß cells of endocrine pancreas (islets of Langerhans)
Effect: ↓ blood [glucose]; ↑ glycogen + fat storage
-absent or ineffective in DM
Glucagon
Peptide
α cells of endocrine pancreas (islets of Langerhans)
Effect: ↑ blood [glucose]; ↓ glycogen + fat storage
Somatostatin (SS)
Peptide
σ cells of endocrine pancreas (islets of Langerhans)
Effect: inhibits many digestive processes
Testosterone
Steroid
Testes
Effect: male characteristics, spermatogenesis
Estrogen
Steroid
Ovaries/placenta
Effect: female characteristics, endometrial growth
Progesterone
Steroid
Ovaries/placenta
Effect: endometrial secretion, pregnancy
Atrial natriuretic factor (ANF)
Peptide
Heart
TO: kidney
Effect: ↑ urination to ↓ BP