Chapter 8: Genetics Flashcards
(59 cards)
Genetics
Study of the transfer of genes from parents to offspring
The nature in nature vs nurture
Genotype is an organism’s genetic makeup
Phenotype is how genes are expressed
Animal Breeding
Humans have understood for centuries that parents pass traits to offspring
Through domestication humans selectively bred individuals for desired traits
Docility, intelligence, strength, coat quality, fat content, milk production, appearance
Genetics: What are Genes?
Nucleus holds chromosomes
Chromosomes are made of DNA
Pairs of chromosomes
Genes are segments of DNA
Code for specific proteins, control biochemical processes
Blueprint of life
DNA
Deoxyribonucleic acid
Double strand of nucelotides= deoxyribose sugar, phosphate, nitrogenous base
Purines- adenine (A) and guanine (G)
Pyrimidines- thymine (T) and cytosine ©
A to T and G to C
Genes are made of sequence of base pairs
Genome
Genome is all the genes for an organism
Different species have different numbers of chromosomes, genes
DNA must be supercoiled to fit thousands of genes per chromosome
Somatic Cells
Somatic cells- body cells have 2 pairs, diploid (2n)
Humans- 46, 23 pairs
Gametes
reproductive cells 1 pair, haploid (n)
Sex Chromosomes
have genes related to sex characteristics, Autosomes- everything else
Sex Determination
In mammals males are XY (sperm), females are XX (egg)
In chickens females are ZW, males are ZZ
Crocodilians, turtles temperature dependent
Amphibians, fish lots of forms of determination
Chromosome Number
Expressed as n, Varies widely
Polyploidy
more than 2 copies of chromosomes, or whole genome
Mistake during cell division
Not common in vertebrates, widespread in plants, can cause low seed production
Aneuploidy
variation in number of individual chromosomes
Monosomic
one less (2n-1)
Trisomy
one more (2n+1)
Often lethal, sometimes not.
Down’s syndrome caused by Trisomy of chromosome 21
DNA Replication
Must be accurate to prevent mistakes in offspring
DNA molecule unzips, RNA primer attaches to DNA polymerase
Polymerase moves down original strand
Bonds new nucleotides together to original strand, polymerization
DNA Replication: When do we do it?
Anytime body cells (somatic cells) divide
Growth, injury, maintenance
Anytime sex cells (gametes; sperm, eggs) divide
Reproduction
Mitosis
Somatic cell division, produces two 2n cells- 2 copies of chromosomes
Meiosis
Reproductive cell division, produces 4 n cells-1 copy of chromosomes
Principle of Inheritance
1866 Gregor Mendel discovered principles of inheritance while studying pea plants
Alleles
forms of a given gene, each creates different proteins, so express traits differently, get one copy from each parent
Chromosomes in homologous pairs, genes for the same traits
Locus
is a certain spot on chromosome
Animals with matching alleles at a locus
Homozygous, (AA or aa) different alleles are Heterozygous (Aa)
Inheritance
is passing of alleles in gametes
gamete production
pairs separate