Chapter 9: Quick clinical references Flashcards Preview

Quick Reference Handbook for Surgical Pathologists > Chapter 9: Quick clinical references > Flashcards

Flashcards in Chapter 9: Quick clinical references Deck (72)
Loading flashcards...
1

What carcinomas disseminate hematogenously?

Renal cell carcinoma

Follicular carcinoma of thyroid

Choriocarcinomas

Prostate (via spinal venous plexus)

2

Which sarcomas tend to spread to lymph nodes?

Clear cell sarcoma / melanoma of soft parts

Epithelioid sarcoma

Alveolar rhabdomyosarcoma

Synovial sarcoma

Malignant fibrous histiocytoma

Angiosarcoma

3

What tumors are known to have very late metastases?

Renal cellc arcinoma

Salivary gland carcinoma (especially ACC)

Breast cancer

Carcinoids

Melanoma

Granulosa cell tumor of the ovary

Sarcomas

4

In which organs are metastatic tumors more common than primary tumors?

Liver

Lung, pleura

Heart

Bone (in adults)

Brain

Adrenal

5

What four organs are the most common sites of metastasis?

Lung, liver, bone, brain

6

What are the four most common causes of metastatic disease in children?

Clear cell sarcoma of kidney

Rhabdoid tumor

Wilms tumor

Neuroblastoma

7

What organs of origin are most responsible for carcinomas of unknown primary?

Pancreaticobiliary

Lung

Gastric

8

What tumors tend to create the following pattern of lung metastases?

1. Solitary nodule
2. Lymphangitic
3. Bronchioloalveolar
4. Pleural seeding
5. Miliary

1. Sarcoma, melanoma, colorectal, germ cell

2. Breast, sotomach, pancreas, lung, prostate

3. Pancreticobiliary

4. Lung, breast, ovary, thymoma

5. Thyroid, RCC

9

Metastases to & from:

Adrenal

To: Liver, lung, peritoneal/pleural, bone

From: Lung, breast, kidney, stomach, pancreas

10

Metastases to & from:

Anus

To: Liver, lung

From: None

11

Metastases to & from:

Bone

To: None

From: Lung/thyroid/kidney (osteolytic), prostate (osteoblastic), breast (either)

12

Metastases to & from:

Bladder

To: Lung, bone, liver

From: None

13

Metastases to & from:

Brain

To: None

From: Lung, breast, melanoma, RCC, colon, thyroid

14

Metastases to & from:

Breast

To: Lungs, bone, liver, brain, adrenal (IDC)
Unusual sites (ILC)

From: None

15

Metastases to & from:

Colon

To: Liver, peritoneum, lung, ovaries

From: None

16

Metastases to & from:

Carcinoids

To: Liver, then lung, then bone.

From: N/A

17

Metastases to & from:

Cervix

To: Lung

From: None

18

Metastases to & from:

Uterus

To: Lung, vagina, peritoneum

From: None

19

Metastases to & from:

Ovaries

To: Lungs, pleura, peritoneum (duh)

From: Colon?

20

Metastases to & from:

Liver

To: Lung, bone, adrenal (both HCC & cholangio)

From: Other GI, breast, lung, kidney, melanoma, peds stuff

 

21

Metastases to & from:

Lung

To: Adrenal, bone, brain

From: Any carcinoma, melanoma, sarcoma, germ cell tumors...

22

Metastases to & from:

Melanoma

To: Anywhere.

From: N/A

23

Metastases to & from:

Meninges

To: None (direct extension into brain?)

From: Melanoma, breast, leukemias

24

Metastases to & from:

Pancreas

To: Liver, peritoneum, lung (alveolar spread)

From: None

25

Metastases to & from:

Parathyroid

To: Lung, liver, bone

From: None

26

Metastases to & from:

Pheochromocytoma

To: Bone (always need bone scan), liver

From: N/A

27

Metastases to & from:

Pleura

To: None

From: Lung, breast, but really any organ

28

Metastases to & from:

Prostate

To: Axial skeleton (via hematogenous spread of spinal cord venous plexus), lung, liver, adrenal.

29

Metastases to & from: RCC

To: Lung, bone, liver, brain, adrenal.

From: Plasma cell myeloma?

30

Metastases to & from:

Salivary gland

To: Lung