Chapter Fourteen: Psychoneuroimmunology and Immune-Related Disorders Flashcards
(78 cards)
Def: Psychoneuroimmunology
interactions among different processes of adaptation.
Includes: behavioral, neuroendocrine, & immunological
Def: immune system
Distinguishes between what is self & what is foreign.
Attacks & rids the body of foreign invaders
Def: Natural Immunity
generalized defense against pathogens.
Def: Specific Immunity
response to a specific invader.
Immune Functioning research has looked at &….
Assesses the functioning of immune cells
Assesses the production of antibodies to latent viruses
Assessing levels of immune system products
Using indirect measures
“Levels of _______ to these latent viruses constitute a measure of how _____ the immune system is functioning”.
antibodies, well
How do researchers use healing or tape striping to study immune functioning?
Wounds typically heal quicker when it’s functioning at a fast rate.
By using this, researchers make a small wound, and then they look at how fast the wound heals over.
This requires a sort of “waxing” technique but with no wax to see how fast the skin heals
Stress + Immunity:
Different kinds of stressors require different kinds of defenses
Maximally efficient immune responses to any situation entails costs
Immediate short term stressors produces a pattern of immune responses
Brief stressors lead to a shift from cellular immunity & toward humoral immunity
Chronically stressful events have adverse effects
Health risks of stress:
Increased vulnerability to infectious diseases
Stress predicts more severe illness & higher production of cytokines among ppl who are already sick
Autoimmune disorders are affected by stress
Studies on stress…
Studies show the relation of stress to immune functioning has a variety of naturalistic stressors.
Involves the effects of natural disasters & other traumas on immune functioning.
Indicates that self-related emotions could cause an increase in inflammation processes.
Stress ____________ immune functioning
compromises
Depression is associated with…
Decrease in cellular immunity
Prolonged inflammatory responses
Delayed wound healing
Sleep disturbance
Positivity is linked to _______ wound healing.
quick
Stress + Immune functioning + relationships = what?
Lonely ppl have worse health & immunocompromise
Ppl with insecure attachments to others show lower natural killer (NK) cell cytotoxicity
Chronic interpersonal stress predicts inflammatory activity over time
Marital status + stress + immune functioning = what?
Separated & divorced women show worse immune functioning
Partner violence has been tied to adverse changes in immune functioning
Risks are higher for women than men.
Marital issues are tied to adverse changes in immunity.
Caregiving + immune functioning + stress = what???
Stressful for ppl who provides care for a friend or family member with a long term illness
Caregivers that experience emotional distress might be at risk for adverse effects on the immune system.
May also be exposed to infection due to high cortisol.
Protective effects of psychosocial resources:
Social support provides a buffer against adverse immune change in response to stress
Resources (money) limits deterioration in immune functioning.
Optimism + immune functioning = what??
Important influence on stress related stress & immune changes
Personal control or benefit finding:
Ppl who consider stressors as uncontrollable show adverse immune effects
Factors that have beneficial effects on immune functioning
Prioritizing goals
Emphasizing relationships, personal growth, & ones’ meaning in life
Relaxation + stress + immune functioning = what?
Mutes the effects of stress on the immune system
Interventions have significant effects on the immune system & on health outcomes
Def: Acquired Immune Deficiency Syndrome (AIDS)
spreads bc of the high rate of extramarital sex, lack of condom use, & high rate of gonorrhea
Def: Human Immunodeficiency Virus (HIV):
attacks helper T cells & macrophages of the immune system
HIV causes rapid growth in the first few weeks while the infection spreads throughout the body.
HIV after _____weeks, viral growth is gradual. Compromises the immune system by killing off the helper T cells. Creates a vulnerability to opportunistic ___________ which leads to the diagnosis of AIDS.
3-6 , infections
Def: Antiretroviral Therapy (ART)
combo of antiretroviral meds
Reduces sexual transmission if initiated early
Drugs need to be taken regularly to be effective