CHE103:13 Flashcards
(38 cards)
Iconic bond
NH3+-O-
Hydrophobic Interactions
They’re facing away from the inside as if it’s water
Ch/ch3ch3/ch/ch3ch3
Disulfide linkage
-s-s ; pretty self explanatory it’s just two sulfur’s connected
Hydrogen Bonding
OH•••O
Polar Neutral
Amino Acids (6) contain a hydroxyl (-OH), sulfur or amide
Nonpolar
Amino acids (9), contain hydrocarbons or aromatic rings
Acidic
Amino acids (2), contain a carboxylic acid group in the side chain
Basic
Amino acids (3) contain an amino ( may be neutral or charged )
Tertiary
3-Dimensional shape — has multiple ways of bonding
Secondary
Alpha Helix, Beta Sheet, excessive hydrogen bonding { OH•••O}
Primary
Peptide bonds
Quaternary
Same multiple bonds as Tertiary but different subunits
- hemoglobin and insulin are examples of this structure
pH=pl:
0
pH>pl
-1
pH
+1
pH=7.0
NH2-COO-
Lock & Key method implies what about the active site
The active site is a rigid pocket
Competitive Inhibitor
Can be reversed
Polar uncharged
Polar neutral
Rossman Fold
Count +3 or -3, if the number is 203 your answer is either 200 or 206
Condensation
Takes away water (h2o)
Hydrolysis
Adds water (h2o)
Denatures a Protein
- Heat above 50°c
- organic compounds
- pH changes
- Heavy metal ions
- Strong acids/ base
- Iconic compounds (NaCl)
- Detergent
- Agitation
Polypeptide
A sequence of amino acids between 10-100 in length