Chemical Pathology Day 3 Flashcards
(20 cards)
What are the two groups of hormones tested for here at KATH
Thyroid hormones
Fertility hormones
What are the hormonal constituents of the thyroid function test
TSH
Tri-iodothyronine
Thyroxine
What is the interpretation for a raised T3, raised T4 and low TSH
Hyperthyroidism
What is the interpretation for a raised T3, low T4 and low TSH
T3 thyrotoxicosis
What is the interpretation for a normal T3, raised T4 and low TSH
Thyrotoxicosis
What is the interpretation for a decreased T3, decreased T4 and raised TSH
Hypothyroidism
Why should hormone samples be taken in the morning
Concept of circadian rhythm
What tube is used for hormonal assays
Gel separator tube
Fasting is not required for hormonal testing
True or false
True
With the exception of prolactin
What are the constituents of a fertility test
LH
FSH
Prolactin
Progesterone
Testosterone
Estrogen
Which of the fertility tests require a fasting sample
Prolactin
What new chemical hormone is being added to the fertility tests
Anti-Mullerian hormone (to test for egg production)
At what day does progesterone peak at the menstrual cycle
21st day
What does the material and test section on a lab form mean
What material or sample do you need for the test
What are some information to be provided on the lab form
Surname
Other names
(Lead) clinician
Clinical summary and diagnosis
Material and test
Date of request
Signature of the doctor
Time sample taken
Time specimen received
What are some factors that can affect the interpretation of fertility hormone results
Sex of the patient
Age of the patient
Diet
Time of sampling
Stress and anxiety
Posture of the patient (should be standardized if possible. Point posture from lying to standing, there may be an increase of as much as 13% in the concentration of serum proteins due to redistribution of fluid in the extracellular space)
Effect of exercise (some analytes are affected by muscular activity Eg. CK-MB, etc)
Pregnancy (there are changes in body chemicals during pregnancy)
Menstrual cycle
Drug history
Analytical factors (was there any problem during the process of obtaining the results - machine calibration, quality checks)
Artefactual factors
Physical size (creatinine levels)
Hereditary factor (Eg. Sickle cell)
What is the value of the adult total bilirubin up to
3 - 22 umol/l
What is the upper limit for total bilirubin for pre-mature babies
205.2 umol/l
What is the upper limit for total bilirubin for full-term babies (9-months babies)
171 umol/l
Which specific time should hormone samples be taken
Before 10 am
