Chemical Safety & Security, Research and Bioethics, Flashcards

1
Q

What was the primary factor contributing to Shari Sangji’s death in the lab accident?
a) Her own negligence
b) Lack of proper safety measures
c) Unforeseeable chemical reaction
d) Insufficient first-aid response

A

b) Lack of proper safety measures

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2
Q

UCLA’s chemistry department was cited for inadequate safety measures, including the lack of appropriate _____ and insufficient _____.

A

protective clothing, safety training

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3
Q

TF: Dr. Gibson believes prioritizing safety in labs is solely the responsibility of individual researchers.

A

False (He emphasizes universities’ role)

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4
Q

Why is the Shari Sangji case significant beyond the tragic outcome?

A

It highlights the need for a cultural shift towards prioritizing safety within research institutions.

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5
Q

What collective effort is crucial to minimizing laboratory accidents?

A

Enhanced safety education and culture within the scientific community

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6
Q

Give an example of an ethical dilemma faced by researchers.

A

Deciding whether to keep or return a valuable item found during research.

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7
Q

What is the key difference between ethics and laws in research?
a) Ethics are subjective, while laws are objective.
b) Ethics are enforced through social pressure, while laws have legal consequences.
c) Ethics apply to all research, while laws are specific to certain disciplines.
d) There is no significant difference.

A

b) Ethics are enforced through social pressure, while laws have legal consequences.

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8
Q

TF: Plagiarism and fabrication of data are examples of unethical behavior in research.

A

True

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9
Q

What are some core ethical values guiding research conduct?

A

Honesty, transparency, and confidentiality

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10
Q

Ethical standards are universally the same across all research fields and institutions.

A

False (Variations exist based on region, discipline, etc.)

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11
Q

What is the primary function of ethics committees in research?

A

Reviewing and monitoring research proposals to ensure ethical compliance.

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12
Q

What are the three core principles guiding ethical decisions, as outlined in the Belmont Report?

A

Respect, beneficence, and justice

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13
Q

Provide two instances of highly unethical research practices.

A

Piltdown Man hoax and Tuskegee experiment

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14
Q

What are some potential consequences of unethical research?
a) Loss of trust in science and the research community
b) Harm to research participants
c) Primarily financial repercussions for the researchers
d) Both a and b

A

d) Both a and b

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15
Q

What are two historical actions taken to prevent unethical research practices?

A

Nuremberg Code and National Research Act

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16
Q

Why is ethical training crucial for researchers?

A

It equips them to navigate ethical dilemmas and uphold responsible research practices while making discoveries.

17
Q

How does ethics training benefit researchers in their work?

A

It helps them maintain moral integrity and make ethically sound decisions throughout the research process.

18
Q

What is “cherry-picking” data?

A

Selectively choosing favorable data to misrepresent the truth in visualizations.

19
Q

How can reporting bias from veterinarians skew the public perception of a drug’s effectiveness?

A

If they only report successful trials, it creates an inaccurate impression of the drug’s overall efficacy.

20
Q

Industry-funded studies of drugs are generally less likely to show positive results than government-funded ones.

A

False (They are often more likely to show positive outcomes)

21
Q

What is the potential danger of using cumulative data visualizations?

A

It can create a misleading impression of continuous growth, even if the actual increases are minimal.

22
Q

How can pie charts be misused to present misleading information?

A

When participants can vote for multiple options, the total percentages can exceed 100%.

23
Q

What ethical dilemma arises in cases of conjoined twins?

A

Separation surgery often presents a life-threatening risk to one of the twins.

24
Q

What field of study helps navigate complex ethical issues arising in medicine and biology?

A

Bioethics

25
Q

What are some ethical concerns associated with transgenic organisms?

A

Potential harm caused by untraceable compounds introduced into the organism and long-term, unforeseen consequences on the genetic composition of future generations.

26
Q

Why are model organisms used in research, despite the ethical questions it raises?

A

They are essential tools for testing medicines and other interventions, but their use raises questions about their well-being and the ethical implications.

27
Q

What is the role of regulatory bodies in the context of bioethics?

A

To oversee and regulate biotechnological activities, ensuring they adhere to ethical principles and minimize potential harm.

28
Q

What are some primary ethical concerns surrounding human cloning?

A

Overpopulation, loss of genetic diversity, and the potential physical and psychological harm to the cloned individual.