Chemistry In Everyday Life 👾 Flashcards
(20 cards)
Drugs molecular mass
100 to 500 units
Analgesics
Painkilling effect
Antiseptics
Killer or arrest the growth of organisms
On the basis of drug action
All anti histamines inhibit the action of compound and histamine which causes inflammation in the body
On the basis of chemical structure
Sulfonimize have common structure features same pharmalogical activity
On the basis of molecular targets
Drugs usually interact with biomolecule such as carbohydrates lipids proteins and nucleic acids these are called target molecules or drug targets
Enzymes
Proteins which perform the role of biological catalyst in the body are called enzymes
Receptors
Proteins which are crucial to communication system in the body
Carrier proteins
The carry polar molecules across the cell membrane
Two major functions of enzymes
First hold substrate for a chemical reaction active sites of enzymes for the substrate molecule in a suitable position so that it can be attacked by the reagent effectively second thing is to provide the functional group that will attacked the substrate and carry out chemical reaction this is catalytic action of enzymes
Drug enzyme interaction and enzyme inhibitors
Drug stop any of the above activities of enzymes these can block the binding side of the enzyme and prevent the binding of substate or can inhibit the catalytic activity of the enzyme such drugs are called enzyme inhibitors
Two types of enzyme inhibitors
First one is competitive inhibitors which come in place of the substrate second one is which bind to allosteric site and change the shape of the active site
Receptors drug targets
Body communication system. present in cell membrane. small part processing active site projects out the surface and membrane and opens in the outside region of the cell. message between two neurons are neurone to muscle receive ad binding sites of receptor proteins. Transfer message into sell without entering the cell.
Agonist and antagonist
Agonist drug that mimic the natural messenger by switching on receptor useful while lack of chemical messenger. Antagonist drugs that bind to receptor site and inhibit natural function useful when blocking of messages
Antacids
Reduces or neutralizers acidity example baking soda metal hydroxide
What does histamine do and what is used to prevent it
Histamine stimulance the secretion of pepsin and HCL in the stomach the drug cimetidine(tagmet) was designed to prevent the interaction of histamine with receptors present in the stomach wall test result in the release of lesser amount of acid
Largest selling antacid
Zantac-ranitidine
Examples of antihistamines
Bromopheniramine- dimetapp(BD)
Terfenadine-Seldane (TS)
Tranquilizers
Using treatment of stress mild or even severe mental diseases anxiety stress irritability or excitement by increasing a sense of will be essential component in sleeping pills. Nora adrenaline responsible for mood changes when Nora adrenaline is in low levels signal sending activities low that causes depression then doctors prescribe anti depressing drugs.
Types of tranquilizers and examples
Strong tranquilizers that is Iproniazid and Phenelzine(nardil)
Mild tranquilizers that are Choloridiazepoxide ,Meprobamate, Equanil
Barbiturates- hypnotic drugs produce sleep