Chemotherapeutics

Question 1

What is the chemotherapeutic agent to treat periodontitis

Answer 1

NONE – no chemothehrapeutics can treat periodontitis

Question 2

percentage of chlorohexidine in mouthwashes available by prescription

Answer 2

0.12%

Question 3

Mouthwashes substantivity

Answer 3

want this to be high

like chlorohexidine BINDS to some things

dont want low – because it will rinse out of the oral cavity too quickly

Question 4

gold standard of mouth washes

Answer 4

chlorohexidine

Question 5

gum butler version of chlorohexidine

Answer 5

no alcohol - so good for patients that are recovering alcoholics or do not want it in their wash

Question 6

substantivity of chlorohexidine and characteristics and use

Answer 6

between 12-18 hours

2x a day
alcohol content is 12% and pH is 5.5

it is positively charged and is attracted to the surfaces of the teeth and oral soft tissues

Question 7

middle of the road mouthwashes effects in terms of plaque

Answer 7

they have plaque inhibitory effects but LACK ANY TRUE ANTO-PLAQUE effectts

-these include listerine

Question 8

listerine characteristics

Answer 8

• considered an essential oil
• 26.9% alcohol and pH of 5.0 - non prescription phenolic compound containing essential oils

-

Question 9

active ingredient in listerine

Answer 9

essential oils

Question 10

why alcohol in mouthwashes

Answer 10

so the active ingredients to stay effective and not denature

Question 11

is listerine charged and implicatino

Answer 11

no - so low substantivity (unlike chlorohexidine)

Question 12

method of action in listerine

Answer 12

alterations in the bacterial cell wall

Question 13

method of action in listerine

Answer 13

alterations in the bacterial cell wall

Question 14

adjunctive therapies to plaque removal

Answer 14

very limited

Question 15

CPC?

Answer 15

active ingredient in the ‘bottom of the barrel’ of mouth washes

Question 16

CPC?

Answer 16

Cetyl pyridinium chloride

active ingredient in the ‘bottom of the barrel’ of mouth washes

0.05% in Cepacol or scope 0.045%

Question 17

use of iodine?

Answer 17

prevention in skin infections and treatment of wounds

• broad spectrum bactericide - effective against yeasts, molds, bacteria,

Question 18

use of Povidone iodine?

Answer 18

prevention in skin infections and treatment of wounds

• broad spectrum bactericide - effective against yeasts, molds, fungi, viruses and proteases

Question 19

stannous flouride

Answer 19

also the additional benefit of inhibiting plaque accumulation

Question 20

oxygenating agents

Answer 20

hydrogen peroxide and buffered sodium peroxyborate and peroxycarbonate in mouth rinses have a beneficial effect probably by inhibiting ANEROBIC bacteria

• as obligate anerobes are important in development of gingivitis and periodontitis

Question 21

down fall of oxygenating agents

Answer 21

most bacteria that are anaerobic and involved in periodontitis are subgingival

Question 22

down fall of oxygenating agents

Answer 22

most bacteria that are anaerobic and involved in periodontitis are subgingival

Question 23

are there ADA approved products in terms of oxygenating agents

Answer 23

NO

Question 24

pre-brushing rinse?

Answer 24

no effect on plaque what so ever

Question 25

plax - active ingredient?

Answer 25

contain detergents - pre brush rinse - worthless - claims to loose plaque prior to brushing 7.5% alcohol sodium benzoate and that combined with soaping agents may have a surfactant action on plaque not ADA approved

Question 26

plax - active ingredient?

Answer 26

contain detergents - pre brush rinse - worthless - claims to loose plaque prior to brushing 7.5% alcohol sodium benzoate and that combined with soaping agents may have a surfactant action on plaque not ADA approved

Question 27

dentifrices and general use

Answer 27

toothepaste promote oral hygiene - aid in removal of plaque removal from teeth - elimination and or masking of halitosis and as a delivery agent for active ingredients such as fluoride

Question 28

dentifrices and general use

Answer 28

toothepaste promote oral hygiene - aid in removal of plaque removal from teeth - elimination and or masking of halitosis and as a delivery agent for active ingredients such as fluoride

Question 29

essential cleaning in tooth paste and brushing

Answer 29

more mechanical action of brushing than the paste active chemicals

Question 30

dentifrices and general use

Answer 30

toothepaste promote oral hygiene - aid in removal of plaque removal from teeth - elimination and or masking of halitosis and as a delivery agent for active ingredients such as fluoride so - minimize plaque build up - provide an anti-caries effect - remove stain - freshen breath

Question 31

essential cleaning in tooth paste and brushing

Answer 31

more mechanical action of brushing than the paste active chemicals

Question 32

tarter control in dentifrices?

Answer 32

tarter = calculus

Question 33

tarter aka

Answer 33

calculus

Question 34

triclosan

Answer 34

broad spectrum anit-microbrial | - can be found in mouth rinses and toothpastes in europe but ONLY AVAILABLE in COLGATE TOTAL

Question 35

COLGATE TOTAL importance

Answer 35

triclosan and its ability to be anti-gingivitis

Question 36

co-polymer with triclosan

Answer 36

protects stability of the molecule increases the substantivity of triclosan

Question 37

COLGATE TOTAL importance

Answer 37

triclosan and its ability to be anti-gingivitis - paste has demonstrated anti-plaque and anti-gingivitis properties that have earned FDA approval and ADA acceptance for its ability to prevent and reduce gingivitis

Question 38

co-polymer with triclosan

Answer 38

protects stability of the molecule increases the substantivity of triclosan

Question 39

questions about triclosan

Answer 39

chlorinated aromatics - containing one or more benzene rings with one or more chlorine atoms bound to carbon atoms - toxic chlorinated dioxins and furans and PCB's

Question 40

parodontax

Answer 40

has stannous flouride which helps with plaque accumulation and claims to reduce by 40% * says it helps to prevent bleeding gums - but any toothepaste can do this as long s brushing correctly

Question 41

irrigation of the periodontal tissues?

Answer 41

never a mono-treatment - adjunctive therapy - hjelp suppress bacterial etiologic agents - supra- and sub- gingival irrigation is to non- specifically reduce microbial deposits that may induce periodontal diseases