Chemotherapy Flashcards by Yoshita Somarouthu

Short Acting Sulfonamide

Sulfadiazine

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Intermediate Acting Sulfonamide

Sulfamethoxazole

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Long Acting Sulfonamide

Sulfadoxine
Sulfamethopyrazine

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Special purpose Sulfonamide

Sulfacetamide sodium
Sulfasalazine
Silver sulfasalizine
Mafenide

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Adverse Effects of Sulfonamide

Renal Irritation, hematuria, albuminiuria and crystalluria
Allergic reactions
Anorexia, nausea
Hemolytic anemia
Kernicterus

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Uses of Sulfonamide

CUT Masti UNTIL Top Score is Reached
Chanchroid
UTI
Toxoplasmosis
Malaria
Ulcerative colitis
Nocardiosis
Trachoma
Inclusion conjunctivitis
Lymphogranuloma venerum
Topical
Streptococcus pharyngitis
Rheumatoid arthritis

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Uses of Cotrimoxazole

CTRM Murders Bacterial Pathogens in Urinary Tract
Chanchroid
Thyroid
Resp tract inf
Melioidosis
Bacterial gastroenteritis
Pneumocystis jiroveci inf
Urinary tract inf

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Non fluorinated quinolone

Nalidixic Acid

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Fluoroquinolones - First gen

Norfloxacin
Ciprofloxacin
Ofloxacin
Perfloxain

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Flouroquinolones - Second Gen

Levofloxacin
Moxifloxacin
Gemifloxacin
Prulifloxacin
Lomefloxacin
Sparfloxacin

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Uses of fluoroquinolones

FQ Usually GET RID of Several Bacteria Common To Man

UTI
Gonorrhea
Eye infection
Typhoid
Resp sys inf
Intra abdominal inf
Diarrhea
Septicemia
Bacterial prostatitis
Chanchroid
Tuberculosis
Meningococcal carrier state
Anthrax
Neutropenia pts

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Adverse Effects of fluoroquinolones

Nausea, vomiting, abdominal discomfort, diarrhea, skin rashes
Tendonitis
CNS effects - headache, dizziness, insomnia
QTc prolongation

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Natural Penicillin

Benzyl Penicillin
(Penicillin G)

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Semisynthetic Penicillin
Acid resistant alternative

Phenoxymethyl Penicillin

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Semisynthetic Penicillin
Penicillin Resistant Penicillin

Methicillin
Cloxacillin
Dicloxacillin

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Semisynthetic Penicillin
Extended Spectrum Penicillin
Amino Penicillins

Ampicillin
Bacampicilin
Amoxicilin

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Semisynthetic Penicillin
Extended Spectrum Penicillin
Carboxy Penicillins

Carbenicillin
Ticarcillin

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Semisynthetic Penicillin
Extended Spectrum Penicillin
Ureido Penicillins

Piperacillin
Mezlocillin

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Beta Lactamase Inhibitors

Clavulanic acid
Sulbactam
Tazobactam

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Repository Penicillins

Procain Penicillin
Benzathine Penicillin

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Adverse Effects of Penicillins

Hypersensitivity - skin rashes, urticaria, pruritis, fever etc
Local - Pain at site of injection
Jarisch Herxheimer rxn

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Uses of Penicillin G

PADMA STOPS Syphilis

Pneumococcal
Anaerobic
Diphtheria
Meningococcal
Actinomycosis
Staphylococcal
Tetanus
Others
Prophylactic
Streptococcal
Syphilis

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Uses of Ampicillin

R U Mad To Say Bye Bye to ampicillin

Respiratory tract inf
UTI
Meningitis
Typhoid
Septicemia
Bacillary dysentery
Bacterial endocarditis

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Cephalosporins
First Generation
Oral

Cephalexin
Cefadroxil

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Cephalosporins First Generation Parenteral

Cefazolin

Cephalosporins Second Generation Oral

Cefaclor Cefuroxime axetil Cefprozil

Cephalosporins Second Generation Parenteral

Cefuroxime Cefoxitin

Cephalosporins Third Generation Oral

Cefixime Cefpodoxime proxetil Cefdinir Ceftibuten Ceftamet pivoxil

Cephalosporins Third Generation Parenteral

Cefotaxime Ceftriaxone Ceftizoxime Ceftazidime Cefoperazone

Cephalosporins Fourth Generation Parenteral

Cefepime Cefpirome

Cephalosporins Fifth Generation Parenteral

Ceftaroline fosamil Ceftobiprole medocaril

Adverse Reactions of Cephalosporins

Cephalosporins Have Benn Doing Well Day and Night in patients Hypersensitivity Bleeding Diarrhea WBC low count Disulfiram like Reactions Nephrotoxicity Pain at injection site

Carbapenems

Imipenem Meropenem Ertapenem Doripenem Faropenem

Monobactem

Aztreonam

Short Acting Tetracyclines

Chlortetracycline Tetracycline Oxytetracycline

Intermediate Acting Tetracycline

Demeclocycline Methacycline

Long Acting Tetracycline

Doxycycline Minocycline

Glycylcycline Tetracycline

Tigecycline

Adverse Effects of Tetracycline

SHARP CT Light Suprainfection Hepatotoxicity Antianabolic effect Renal toxicity - Fanconi's Syndrome Phototoxicity Pseudotumour cerebri Teratogenicity Long term use - leukocytosis Diabetes insipidus GIT - nausea vomiting Hypersensitivity reactions Thrombophlebitis

Adverse Effects of Chloramphenicol

GI disturbances - nausea, vomiting, Diarrhea Bone marrow depression Gray baby syndrome Superinfection

Aminoglycosides - Systemic

Gentamicin Tobramicin Sisomicin Streptomycin Amikarcin

Aminoglycosides - topical

Neomycin Framycetin

Adverse Effects of aminoglycosides

Ototoxicity Nephrotoxicity Neuromuscular blockade

Uses of aminoglycosides

Gram -ve infections Bacterial endocarditis Tuberculosis - streptomycin Plaque Tularemia Brucellosis Atypical mycobacteria Gut sterilization- neomycin Hepatic coma - neomycin Topical - burns and wounds

Macrolide Antibiotics

Erythromycin Roxithromycin Clarithromycin Azithromycin Spiramycin

Lincosamide Antibiotics

Clindamycin Lincomycin

Aminocyclitol Antibiotic

Spectinomycin

Glycopeptide antibiotics

Vancomycin Teicoplanin

Oxazolidinones

Linezolid Tedizolid

Lipopeptide antibiotic

Daptomycin

Urinary Antiseptics

Nitrofurantoin Methenamine mandelate/ Hexamine Nalidixic acid

Antitubercular First Line Drugs

Isoniazid Rifampicin Pyrazinamide Ethambutol Streptomycin

Antitubercular Second line - Fluoroquinolones

Ofloxacin Levofloxacin Moxifloxacin Ciprofloxacin

Antitubercular Second Line Oral Drugs

Ethionamide Prothionamide Cycloserine Terizidone Paraamino salicylic acid Rifabutin Rifapentine

Antitubercular Second Line Injectable Drugs

Kanamycin Amikacin Capreomycin

Antileprotic Drugs

Dapsone Clofazimine Rifampicin Ethinamide Ofloxcin Moxifloxacin Minocycline Clarithromycin

Polyene antibiotics

Amphotericin B Nystatin Hamycin Natamycin

Imidazoles

Clortrimazole Econazole Miconazole Ketoconazole Butaconazole Oxiconazole Sulconazole Sertaconazole Isoconazole

Triazoles

Fluconazole Itraconazole Terconazole Voriconazole Posaconazole Ravuconazole Isavuconazole

Allylamines

Terbinafine Naftifine

Drugs acting on cell wall - Pneumocandins/echinocandins

Caspofungin Micafungin Anidulafungin

Drugs acting on nucleus

Griseofulvin Flucytosine

Chemotherapy Flashcards

(73 cards)