Chlamaydia

Question 1

General Characteristics (3)

Answer 1

OBLIGATE INTRACELLULAR pathogens

NO PEPTIDOGLYCAN in cell wall

Not produce ATP —> Need host ATP —> ENERGY PARASITES

Question 2

Growth Cycle

Answer 2

BIPHASIC life cycle

1- Elementary body —> EXTRACELLULAR form, INFECTIVE form

2- Reticulate body —> INTRACELLULAR form, REPLICATIVE form

Question 3

Common pathogens (3)

Answer 3

C.trachomatis

C.psittaci

C.pneumoniae

Question 4

C.trachomatis- Ocular Infections (3)

Answer 4

Trachoma:

• Common in children
• Spread by flies or fingers
• Important cause of blindness

Adult Inclusion Conjunctivitis:

• Spread from genitalia to eye
• Common in sexually active young individuals
• Self-limiting

Chlamaydial Ophthalmia Neonatorum:

• Neonates 1-3 weeks after birth
• Mother birth canal is source

Question 5

C.trachomatis- Genital Infections (Males) (2)

Answer 5

Non-gonococcal urethritis

Genital ulcer + Lymphadenopathy —> LYMPHGRANULOMA VENERUM

Question 6

C.trachomatis- Genital Infections (Females) (3)

Answer 6

Urethritis + Cervicitis

Endometriosis + Salpingitis

Ectopic pregnancy + Infertility

Question 7

C.trachomatis- Respiratory Infections (1)

Answer 7

Neonatal pneumonitis

Question 8

C.pneumoniae (4)

Answer 8

Otitis media

Sinusitis

Pneumonia

Bronchitis

Question 9

C.psittaci (5)

Answer 9

PSITTACOSIS or ORNITHOSIS

• Non-human pathogen / Zoonotic infection
• Droplet infection
• Bird handlers
• ATYPICAL PNEUMONIA