Chlamydia Flashcards

(51 cards)

1
Q

What is the most common STI in the UK?

A

Chlamydia

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2
Q

What organism causes chlamydia?

A

Chlamydia trahcomatis serovars D-K

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3
Q

Is chalmydia trahcomatis serovars D-K gram negative or gram positive?

A

It gram-negative bacterium

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4
Q

How is chlamydia transmitted?

A

Vaginal intercourse

Oral intercourse

Anal intercourse

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5
Q

What are the four risk factors associated with chlamydia?

A

Young Age

Sexual Intercourse

Multiple Sexual Partners

Sexually Transmitted Infections

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6
Q

In most cases how does chlamydia present?

A

Asymptomatically

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7
Q

Which gender tends to be more asymptomatic?

A

Females

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8
Q

What are the five clinical features of chlamydia - in females?

A

Dysuria

Vaginal Discharge

Pelvic Pain

Vaginal Bleeding

Dyspareunia

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9
Q

What is dysuria?

A

It is defined as painful urination

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10
Q

What are the two type of vaginal bleeding associated with chlamydia?

A

Intermenstrual

Postcoital

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11
Q

What is dyspareunia?

A

It is defined as painful sexual intercourse

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12
Q

What are the three clinical features associated chlamydia - in males?

A

Dysuria

Urethral Discharge

Epididymo-Orchitis

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13
Q

What is epididymo-orchitis?

A

It is inflammation of the epididymis and/or testicle

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14
Q

What is the most common cause of acute epididymo-orchitis in sexual active young adults?

A

Chlamydia

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15
Q

What is the gold standard investigation used to diagnose chlamydia?

A

Nucleic Acid Amplification Tests

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16
Q

When should NAAT be conducted following possible exposure?

A

> 2 weeks

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17
Q

What is a NAAT?

A

It checks directly for the DNA or RNA of the organism

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18
Q

What are the three methods in which NAATs are performed in women?

A

Vulvovaginal swab

Endocervical swab

First catch urine sample

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19
Q

What is the first line method used to perform NAATs in women?

A

Vulvovaginal swab

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20
Q

What are the two methods in which NAATs are performed in males?

A

Urethral swab

First catch urine sample

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21
Q

What is the first line method used to conduct NAATs in males?

A

First catch urine sample

22
Q

What is the method used to conduct NAATs in cases of rectal chlamydia?

23
Q

What is the method used to conduct NAATs in cases of oral chlamydia?

24
Q

When do we retest individuals for chlamydia following initial infection?

25
In which patient group is chlamydia screening available to?
All sexually active men and women between the ages of 15 and 24 years old
26
What are the two conservative management options of chlamydia?
We advise patients on how to prevent further infection We refer them to contact tracing of sexual partners
27
In women and asymptomatic males, which partners should be contacted for tracing?
All partners from the last six months or the most recent partner
28
In symptomatic males, which partners should be contacted for tracing?
All partners since, and in the four weeks prior to the onset of features
29
When do we treat contacts of confirmed chlamydia cases?
It should be offered prior to the results of their investigation being known
30
What is the first line pharmacological management option of chlamydia?
Doxycycline
31
What dose of doxycycline is used to treat chlamydia?
100mg twice a day for 7 days
32
What is a common side effect of doxycycline?
Light sensitivity
33
What are the two contraindications of doxycycline?
Pregnancy Breastfeeding
34
What are the three second line pharmacological management options of chlamydia?
Azithromycin Erythromycin Amoxicillin
35
What dose of azithromycin is used to treat chlamydia?
A stat dose of 1g, followed by 500mg once daily for two days is administered
36
What dose of erythromycin is used to treat chlamydia?
500mg four times daily for 7 days
37
What dose of amoxicillin is used to treat chlamydia?
500mg three times daily for 7 days
38
During treatment of chlamydia, what advice is given to patients? Why?
We advise patients to abstain from sexual intercourse This is to reduce the risk of re-infection
39
What are the seven complications of chlamydia?
Infertility Pelvic Inflammatory Disease Endometriosis Ectopic Pregnancies Epididymitis Reactive Arthritis Perihepatitis
40
What is another term for perihepatitis?
Fitz-Hugh-Curtis Syndrome
41
What is chlamydia conjunctivitis?
It is defined as chlamydia trochamitis serovars infection of the conjunctiva, due to infected genital fluid coming into contact with the eye
42
Which two patient groups tend to be affected by chlamydia conjunctivitis?
Young adults Neonates
43
How can neonates become infected with chlamydia conjunctivitis?
It can be transmitted from an infected mother during birth
44
What are the three clinical features of chlamydia conjunctivitis?
Conjunctival Erythema Conjunctival Irritation Conjunctival Discharge
45
What is lymphogranuloma venerum?
It is defined as a condition in which chlamydia trochamitis serovars infects the lymphoid tissue between L1-L3
46
What are the two risk factors of lymphogranuloma venerum?
Men Who Have Sex With Men HIV Infection
47
What is the clinical feature associated with the primary stage of lymphogranuloma venerum?
PAINLESS ulcer This can present on the penis, vaginal wall or rectum
48
What is the clinical feature associated with the secondary stage of lymphogranuloma venerum?
Painful inguinal lymphadenopathy
49
What is the clinical feature associated with the tertiary stage of lymphogranuloma venerum?
Proctocolitis
50
What investigation should be conducted to investigate lymphogranuloma venerum? Why?
HIV testing It is more common in individuals who have HIV
51
What is the management option of lymphogranuloma venerum?
We prescribe patients a course of doxycycline 100mg twice daily for 21 days