Chloride

Question 1

What is the chloride shift

Answer 1

Cl- acts as an exchange anion for HCO3- in red blood cells which allows for transport of tissue derived CO2 to the lungs

Question 2

What are the 2 steps of the chloride shift

Answer 2

–Waste CO2 enters the RBC where it is converted to HCO3 by carbonic anhydrase
–A transporter protein transports HCO3 to the plasma at the same time it brings Cl- into the cell

Question 3

The absence of what molecule stops the chloride shift

Answer 3

Cl-; bicarbonate transport stops

Question 4

What makes chloride unique

Answer 4

One of the only anions that can be actively secreted by G.I tract

Question 5

Overall purpose of chloride shift

Answer 5

Keeping a neutral electrochemical balance in cell

Question 6

What is purpose of ion exchange protein in chloride shift

Answer 6

Exchanges chloride for bicarbonate to maintain neutral charged in RBC and plasma

Question 7

3 functions of chloride

Answer 7

• Formation of hydrochloric acid in the stomach
• Needed by white blood cells during phagocytosis to destroy foreign substances
• Chloride shift