Cholesterol

Question 1

hypercholesterolemia Tx

Answer 1

1 Lifestyle changes

2 adherence

Question 2

who should you give statins to? high intensity duh***

Answer 2

patients w
1.- Vascular disease
2.- LDL >=190
3.- LDL 70-189 + 40-75y + DBT
4 LDL 70-189 + 40-75y + High Calculated Risk Score

Canada: 70= 1.8 mmol/L
190= 4.9 mmol/L

Question 3

Calculated Risk Score includes….

Answer 3

HTN
smoking
obesity
age >45 man. >55 woman

Question 4

High-intensity Statin examples

Answer 4

Atorvastatin 40-80

Rosuvastatin 20-40

Question 5

Moderate-intensity Statin examples

Answer 5

Atorvastatin 10-20

Rosuvastatin 5-10

Question 6

who you want to have with moderate intensity statins?

Answer 6

> 75y
OR
Statin intolerance (liver/renal disease)

Question 7

Additional management on Statins administration

Answer 7

Get baseline test of lipids, A1C, CK, LFTs.

Check lipids yearly and + A1C only if DM.

Question 8

when to check CK & LFTs again?

Answer 8

if muscle pain. CK, U/A

if hepatitis symptoms LFTs

Question 9

Statin induced myositys Or hepatitis management

Answer 9

stop the statin. Once it goes away put it back at lower dose

Question 10

Who you would not give statins to?

Answer 10

LDL<70 + no disease

Question 11

FibratesX, example

Answer 11

gemfibrozil

Question 12

fibrates good and bad effects

Answer 12

↓ tc ↑ hdl.

Myositis ↑LFTs

Question 13

fibrate indications

Answer 13

when u can’t use statins

Question 14

Ezetimibe and Bile acid resins good and bad effects

Answer 14

↓ LDL

Diarrhea

Question 15

Niacin good and bad effects

Answer 15

↓ ldl ↑ hdl.

Flushing (prevent w ASA)